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4D Molecular Therapeutics develops gene therapies using its Therapeutic Vector Evolution platform to create adeno-associated virus (AAV) delivery vectors that transport therapeutic genes to patients’ cells. This clinical-stage biotech focuses on genetic diseases such as cystic fibrosis, delivering genetic material through engineered AAV vectors in targeted tissues. Its product approach involves R&D and clinical trials to test safety and efficacy, followed by commercialization through direct sales or partnerships with larger pharmaceutical companies. The company differentiates itself with a proprietary vector evolution technology that enables tailored, precise gene delivery and by pursuing funding and collaborations (e.g., with the Cystic Fibrosis Foundation) to advance therapies like 4D-710. The goal is to bring gene therapies to market to treat serious genetic diseases and improve patient outcomes, funded by equity investments, strategic partnerships, and future product sales.
Industries
Biotechnology
Healthcare
Company Size
201-500
Company Stage
IPO
Headquarters
Emeryville, California
Founded
2013
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Total Funding
$615M
Above
Industry Average
Funded Over
7 Rounds
Flexible Work Hours
4D Molecular Therapeutics (NASDAQ:FDMT) announces quarterly earnings results. August 13, 2026 Key points. * 4D Molecular Therapeutics missed earnings expectations: The company reported a quarterly loss of $1.04 per share versus the $1.02 consensus estimate, while revenue of $3.78 million exceeded expectations of $3.62 million. * Shares fell 1.9% to $11.65 after the results. Analysts maintain a "Moderate Buy" consensus rating with an average price target of $29.75, although ratings range from "Strong Buy" to "Sell." * Insiders sold 197,226 shares worth approximately $2.2 million over the past 90 days, while institutional investors own 99.27% of the company's stock. * Five stocks we like better than 4D Molecular Therapeutics. 4D Molecular Therapeutics (NASDAQ:FDMT - Get Free Report) posted its quarterly earnings data on Thursday. The company reported ($1.04) earnings per share for the quarter, missing analysts' consensus estimates of ($1.02) by ($0.02), FiscalAI reports. 4D Molecular Therapeutics had a negative net margin of 182.34% and a negative return on equity of 36.83%. The firm had revenue of $3.78 million for the quarter, compared to the consensus estimate of $3.62 million. 4D Molecular Therapeutics stock down 1.9%. NASDAQ:FDMT traded down $0.22 during midday trading on Thursday, hitting $11.65. The stock had a trading volume of 705,798 shares, compared to its average volume of 787,133. 4D Molecular Therapeutics has a one year low of $5.97 and a one year high of $14.00. The company has a market capitalization of $609.06 million, a price-to-earnings ratio of -4.53 and a beta of 2.73. The stock has a 50-day moving average of $10.84 and a 200 day moving average of $9.83. Analyst ratings changes. FDMT has been the subject of a number of recent analyst reports. Chardan Capital raised shares of 4D Molecular Therapeutics to a "strong-buy" rating in a research note on Tuesday, July 28th. Weiss Ratings reissued a "sell (d-)" rating on shares of 4D Molecular Therapeutics in a research note on Friday, July 17th. HC Wainwright restated a "buy" rating and set a $36.00 target price on shares of 4D Molecular Therapeutics in a research report on Monday, July 20th. Wall Street Zen downgraded 4D Molecular Therapeutics from a "hold" rating to a "sell" rating in a report on Saturday, May 9th. Finally, B. Riley Financial initiated coverage on 4D Molecular Therapeutics in a report on Friday, July 31st. They set a "buy" rating and a $37.00 price objective for the company. One research analyst has rated the stock with a Strong Buy rating, six have given a Buy rating, one has assigned a Hold rating and one has assigned a Sell rating to the company's stock. Based on data from MarketBeat.com, 4D Molecular Therapeutics has a consensus rating of "Moderate Buy" and a consensus target price of $29.75. Insiders place their bets. In other 4D Molecular Therapeutics news, insider Scott Bizily sold 9,810 shares of 4D Molecular Therapeutics stock in a transaction on Tuesday, June 23rd. The stock was sold at an average price of $12.00, for a total transaction of $117,720.00. Following the completion of the sale, the insider directly owned 8,617 shares of the company's stock, valued at $103,404. The trade was a 53.24% decrease in their position. The sale was disclosed in a document filed with the SEC, which is available at this hyperlink. Also, insider David Kirn sold 12,415 shares of the company's stock in a transaction on Monday, August 3rd. The stock was sold at an average price of $10.05, for a total value of $124,770.75. Following the completion of the sale, the insider owned 871,737 shares of the company's stock, valued at $8,760,956.85. This represents a 1.40% decrease in their ownership of the stock. The SEC filing for this sale provides additional information. Over the last ninety days, insiders have sold 197,226 shares of company stock valued at $2,200,677. 7.90% of the stock is currently owned by corporate insiders. Institutional inflows and outflows. Several hedge funds and other institutional investors have recently added to or reduced their stakes in the business. Martingale Asset Management L P lifted its holdings in 4D Molecular Therapeutics by 12.4% during the fourth quarter. Martingale Asset Management L P now owns 11,775 shares of the company's stock worth $88,000 after buying an additional 1,303 shares during the period. Commonwealth Equity Services LLC purchased a new position in shares of 4D Molecular Therapeutics in the 4th quarter valued at $150,000. Brevan Howard Capital Management LP purchased a new position in shares of 4D Molecular Therapeutics in the 3rd quarter valued at $143,000. ADAR1 Capital Management LLC bought a new position in shares of 4D Molecular Therapeutics in the 3rd quarter worth $145,000. Finally, Bridgeway Capital Management LLC lifted its stake in shares of 4D Molecular Therapeutics by 100.3% during the 2nd quarter. Bridgeway Capital Management LLC now owns 25,000 shares of the company's stock worth $93,000 after purchasing an additional 12,516 shares during the last quarter. 99.27% of the stock is currently owned by institutional investors. 4D Molecular Therapeutics company profile. 4D Molecular Therapeutics, founded in 2015 and headquartered in Emeryville, California, is a clinical-stage biotechnology company focused on the development of targeted gene therapies for rare diseases. The company employs its proprietary Gene Expression AAV (GEA) platform to engineer novel adeno-associated virus (AAV) capsids with enhanced tissue selectivity and transduction efficiency. This platform aims to improve the precision and durability of gene delivery compared to traditional AAV approaches. 4D's pipeline includes both preclinical and clinical-stage programs across multiple therapeutic areas. This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest reporting and unbiased coverage. Please send any questions or comments about this story to [email protected]. Continue following MarketBeat Before you consider 4D Molecular Therapeutics, you'll want to hear this. MarketBeat keeps track of Wall Street's top-rated and best performing research analysts and the stocks they recommend to their clients on a daily basis. MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on... and 4D Molecular Therapeutics wasn't on the list. 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4D Molecular Therapeutics, a late-stage biotechnology company, has secured a strategic credit facility of up to $200 million from Hercules Capital. The California-based firm focuses on developing durable and disease-targeted therapeutics. The funding agreement was announced on 29 June 2026. No further details about the terms of the credit facility or its intended use were disclosed in the announcement.
4D Molecular Therapeutics Inc (FDMT): gene therapy stock made for you? Published on May 20, 2026 at 8:36 am by abdul rahman in news. 4D Molecular Therapeutics Inc (NASDAQ:FDMT) is one of the best gene therapy stocks to buy in 2026. The stock has gained nearly 30% year-to-date and surged more than 190% over the past year. Looking ahead, analysts expect FDMT stock to almost triple in the next 12 months as the company continues to advance its clinical programs. On May 7, 4D Molecular Therapeutics reported its Q1 2026 results and issued operational updates. On the financial side, the company said that it expects to have enough cash to fund its operations at least into the second half of 2028. It closed Q1 with $458 million in cash, cash equivalents, and marketable securities. The company also expects to receive some payments under its arrangement with Otsuka. Regarding its clinical programs, 4D Molecular Therapeutics said it completed enrollment in the 4FRONT-1 Phase 3 trial of 4D-150 ahead of schedule. It said this demonstrates strong investigator and patient enthusiasm for the study. It expects topline data from this study in the first half of 2027. The company expects to complete enrollment in the 4FRONT-2 Phase 3 trial of 4D-150 in the back half of 2026 and expects topline data readout in the second half of 2027. 4D Molecular is developing 4D-150 as a therapy for blinding retinal vascular diseases. The lead indication is wet age-related macular degeneration, which is the subject of the 4FRONT Phase 3 studies. Another indication is diabetic macular edema. 4D Molecular is also advancing programs for geographic atrophy and cystic fibrosis therapies. California-based 4D Molecular Therapeutics Inc (NASDAQ:FDMT) is a biotech company focused on genetic medicines. The company is developing advanced gene therapies that target rare and common diseases in areas like ophthalmology and pulmonology. While we acknowledge the risk and potential of FDMT as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than FDMT and that has 10,000% upside potential, check out our report about this cheapest AI stock.
4D Molecular Therapeutics reported first-quarter revenues of $3.0 million, crushing expectations, though statutory losses reached $1.01 per share. Following the results, shares rose 7.4% to $10.14. Analysts covering the company have revised their 2026 forecasts, now expecting revenues of $15.0 million—an 83% reduction from the past 12 months. Per-share losses are projected to reach $3.92. Whilst analysts lifted revenue estimates, they also increased loss projections to reflect growth costs. The consensus price target remained at $28.22, with estimates ranging from $17.00 to $36.00 per share. Analysts forecast an annualised revenue decline of 91% by end-2026, contrasting sharply with the company's 32% annual growth over the past five years and the industry's projected 22% growth.
4D Molecular Therapeutics (NASDAQ: FDMT) elevates CFO Kristian Humer to Principal Accounting Officer. Filing Impact (Moderate) Filing Sentiment Rhea-AI filing summary. 4D Molecular Therapeutics, Inc. announced a leadership change in its finance function. On March 25, 2026, the Board appointed Kristian Humer as the company's Principal Accounting Officer, effective immediately. He will hold this role in addition to serving as Chief Financial Officer and Principal Financial Officer. Humer succeeds Ashoo Gupta in the Principal Accounting Officer role; Gupta remains Vice President, Finance and Controller. The filing highlights Humer's prior experience as CFO at Foghorn Therapeutics and Viridian Therapeutics and his earlier senior investment banking roles at Citigroup focused on healthcare. 8-K event classification. Item 5.02 - Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers Key figures. Appointment date: March 25, 2026 Age of appointee: 51 years Key terms. Principal Accounting Officer, Principal Financial Officer, Emerging growth company, Item 5.02, +1 more 03/30/2026 - 05:29 PM Faq. What leadership change did 4D Molecular Therapeutics (FDMT) disclose in this 8-K? 4D Molecular Therapeutics disclosed that its Board appointed Kristian Humer as Principal Accounting Officer effective March 25, 2026. He already serves as Chief Financial Officer and Principal Financial Officer, consolidating key finance and accounting responsibilities under a single executive leader. Who is replacing whom as Principal Accounting Officer at 4D Molecular Therapeutics (FDMT)? Kristian Humer is replacing Ashoo Gupta as Principal Accounting Officer at 4D Molecular Therapeutics. Gupta will continue with the company in her existing position as Vice President, Finance and Controller, maintaining continuity in the broader finance organization while shifting the designated accounting officer role. What is Kristian Humer's current role at 4D Molecular Therapeutics (FDMT)? Kristian Humer serves as Chief Financial Officer and Principal Financial Officer and has now been appointed Principal Accounting Officer. This means he oversees the company's overall financial management and is also designated as the primary officer responsible for accounting oversight and related SEC reporting functions. What prior experience does Kristian Humer bring to 4D Molecular Therapeutics (FDMT)? Kristian Humer previously served as Chief Financial Officer at Foghorn Therapeutics and as Chief Financial Officer and Chief Business Officer at Viridian Therapeutics. Before those roles, he spent over a decade at Citigroup Global Markets, most recently as Managing Director in the Healthcare Investment Banking Group. When did the Board of 4D Molecular Therapeutics (FDMT) approve this officer change? The Board of 4D Molecular Therapeutics approved the appointment of Kristian Humer as Principal Accounting Officer on March 25, 2026. The change was effective immediately as of that date, and the company later recorded the event in its current report signed by President and Chief Executive Officer David Kirn. Does Ashoo Gupta remain with 4D Molecular Therapeutics (FDMT) after this change? Yes. Although Ashoo Gupta is no longer designated as Principal Accounting Officer, she continues as Vice President, Finance and Controller. This preserves leadership continuity in the finance team while reassigning the formal Principal Accounting Officer title to Chief Financial Officer and Principal Financial Officer Kristian Humer. Filing exhibits & attachments. 1 document
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Industries
Biotechnology
Healthcare
Company Size
201-500
Company Stage
IPO
Headquarters
Emeryville, California
Founded
2013
Find jobs on Simplify and start your career today