4D Molecular Therapeutics

4D Molecular Therapeutics

Develops gene therapies for genetic diseases

About

4D Molecular Therapeutics develops gene therapies aimed at treating serious genetic diseases by delivering specific genetic material to patients' cells. The company utilizes a unique technology called Therapeutic Vector Evolution to create adeno-associated virus (AAV) vectors, which act as delivery vehicles for therapeutic genes targeting specific cells in the body. Unlike many competitors, 4DMT focuses on precision medicine for genetic disorders, including cystic fibrosis, and operates in a specialized biopharmaceutical market. Their goal is to advance gene therapies through rigorous research and clinical trials, ultimately commercializing effective treatments either directly or through partnerships with larger pharmaceutical companies.

Company Stage

IPO

Employees

201-500

Industries

Biotechnology, Healthcare

Total Funding

$170.2M

Headquarters

Emeryville, California

Founded

2013


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Simplify's Take

What believers are saying

  • Positive interim data from 4D-710 trial boosts confidence in non-invasive therapies.
  • $75 million Series C financing supports pipeline advancement and R&D expansion.
  • Astellas partnership could yield up to $962 million, enhancing commercial prospects.

What critics are saying

  • Public stock offering may dilute existing shareholders' equity, causing dissatisfaction.
  • Analysts cutting estimates suggest potential concerns about near-term financial performance.
  • Ethical concerns may arise from nonhuman primate studies for Fabry therapy.

What makes 4D Molecular Therapeutics unique

  • 4DMT uses proprietary Therapeutic Vector Evolution for advanced AAV vector creation.
  • Focus on aerosolized gene therapies sets 4DMT apart in genetic medicine.
  • Strategic partnerships enhance 4DMT's market position in ophthalmic and genetic diseases.

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Growth & Insights
Headcount

6 month growth

18%

1 year growth

42%

2 year growth

77%

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