Benaroya Research Institute

Benaroya Research Institute

Autoimmune disease research translating to therapies

Overview

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About Benaroya Research Institute

Simplify's Rating
Why Benaroya Research Institute is rated
C+
Rated C on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Biotechnology

Healthcare

Company Size

201-500

Company Stage

Grant

Total Funding

$22M

Headquarters

Seattle, Washington

Founded

1956

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Simplify's Take

What believers are saying

  • BRI won 18 grants totaling $16.2 million in first half 2026.
  • POLARIS Phase 1 GNTI-122 continues with GentiBio and Seattle Children's.
  • May 5, 2026 symposium moved to Bell Harbor, signaling stronger community pull.

What critics are saying

  • Headcount fell from 329 to 315 by March 2026, despite active hiring.
  • BRI depends on NIH and foundation grants; one funding shock squeezes programs quickly.
  • GNTI-122 failure damages BRI's engineered Treg strategy and partner credibility.

What makes Benaroya Research Institute unique

  • BRI targets all 80 autoimmune diseases through shared immunology, not one diagnosis.
  • Edward Irvine joined August 3, 2026, adding protein engineering and AI antibody design.
  • BRI links lab discoveries to POLARIS GNTI-122 and University of Washington collaborations.

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Funding

Total Funding

$22M

Above

Industry Average

Funded Over

2 Rounds

Grant funding comparison data is currently unavailable. We're working to provide this information soon!
Grant Funding Comparison
Coming Soon

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Flexible Spending Accounts: health care, dependent care, commuter

Disability Insurance

Life and AD&D Insurance

Paid Holidays

Paid Vacation

Paid Sick Leave

Employee Assistance Program

Tuition Reimbursement

Commuter Benefits

Wellness Program

Voluntary Benefits

Growth & Insights and Company News

Headcount

6 month growth

1%

1 year growth

1%

2 year growth

1%
Benaroya Research Institute
Aug 3rd, 2026
Press releases.

Press releases. Seattle, WA - Aug 3, 2026 Benaroya Research Institute appoints new principal investigator Edward Irvine, PhD. Benaroya Research Institute (BRI), a world leader in human immunology research, welcomed the addition of Edward Irvine, PhD, as principal investigator and assistant member in the Center for Systems Immunology. "We are very excited to welcome Dr. Irvine," said Jane Buckner, MD, president of BRI. "His research brings new and innovative expertise to BRI. We look forward to seeing how his background in protein engineering and AI helps advance our vision of a healthy immune system for all." The Irvine Lab will combine protein engineering, AI and immunology to study how antibodies communicate with immune cells. A major focus of the lab will be the antibody Fc domain, which helps determine how the immune system responds after an antibody recognizes its target. By uncovering the rules that connect Fc sequence and structure to immune function, the lab aims to design antibodies that direct immune responses with greater precision and support the development of therapies that restore and protect immune health. "I came to BRI because it brings together outstanding scientists and clinicians whose expertise spans many areas of immunology. That creates real opportunities to think creatively about where engineered antibodies could have the greatest impact. I was also drawn to how boldly BRI thinks about what is possible for patients. It truly is an inspiring place to launch a new research program, and I'm excited to contribute," said Dr. Irvine. Prior to joining BRI, Dr. Irvine completed a postdoctoral research fellowship with the Laboratory for Systems and Synthetic Immunology led by Sai Reddy, PhD, at ETH Zurich in Switzerland. During his fellowship, he used protein engineering and AI to develop novel platforms to predict and engineer immune function. Dr. Irvine holds a doctorate in biological sciences in public health with a concentration in immunology and infectious diseases from Harvard University. About Benaroya Research Institute. Benaroya Research Institute (BRI) is a world leader in human immune system research, working to advance the science that will predict, prevent, reverse and cure immune system diseases like allergies, asthma, cancer and autoimmune diseases. BRI accelerates discovery through laboratory breakthroughs in immunology that are then translated to clinical therapies. Benaroya Research Institute believe that a breakthrough in one immune system disease can lead to progress against them all, and work tirelessly toward its vision of a healthy immune system for everyone. BRI is an independent nonprofit research institute affiliated with Virginia Mason Franciscan Health and based in Seattle.

GeekWire
Jan 29th, 2024
Tech Moves: Ex-Amazon Sports Leader Lands At Draftkings; Seattle Tech Vet Launches Advisory Firm

Tech Moves covers notable hires, promotions and personnel changes in the Pacific NW tech community. Submissions: [email protected] Cotter. (Dave Cotter Photo)— Dave Cotter, a longtime Seattle tech leader who sold a startup to Nordstrom and most recently led product at Leafly, launched a new advisory firm called D3 Advisors.“After 30+ years in the operational trenches, I’m now focusing on advising and consulting with startup founders, CEOs, and VC’s, helping them turn great ideas into great companies,” Cotter wrote in a blog post.Cotter was chief product officer at Seattle-based cannabis data and marketplace company Leafly for more than three years before departing in January 2023. He previously co-founded an e-commerce message startup called MessageYes that was acquired by Nordstrom in 2018.Cotter also has exec experience at Amazon, Zulily, SquareHub, and RealNetworks. He’s currently board chair at the Washington Technology Industry Association, and serves on the board of the Technology Alliance.— Johanna Faries, former GM of Call of Duty at Activision, was named president of Blizzard Entertainment. The new role comes as Microsoft just announced a 9% layoff affecting nearly 2,000 employees in its gaming division, three months after the tech giant completed its $69 billion acquisition of Blizzard parent company Activision Blizzard

BioSpace
Sep 12th, 2023
Zura Bio Enters into Sponsored Research Agreement with Benaroya Research Institute

Zura Bio enters into sponsored Research agreement with Benaroya Research Institute.

GeekWire
Apr 11th, 2023
Tech Moves: Adaptive Biotechnologies Coo Departing; Sana Adds Leaders; And More

Tech Moves covers notable hires, promotions and personnel changes in the Pacific NW tech community. Submissions: [email protected] Adams. (Adaptive Photo)— Mark Adams is stepping down as chief operating officer of Adaptive Biotechnologies, the company said today in a regulatory filing.Adams joined the Seattle-based biotech giant more than three years ago. The filing stated that “his service is being terminated by May 2023.”His role will be absorbed by Adaptive’s current president, Julie Rubinstein.“Mark Adams has been instrumental in scaling Adaptive’s operations over the past several years, including putting in place world-class technology and operations leaders,” Adaptive said in a statement to GeekWire. “He is an incredible leader and cultural champion, and we are grateful for his contributions to Adaptive.”Adams was previously managing director of healthcare advanced analytics at SVB Securities and was a principal at Booz Allen Hamilton. He was first hired by Adaptive as chief technology officer.Rubinstein joined Adaptive in 2011 as senior vice president of corporate and business development and became president seven years later

Benaroya Research Institute
Jan 19th, 2023
New Study from Benaroya Research Institute and the University of Washington Identify Novel Mechanism of Regulatory T Cells’ Role in Maintaining Immune System Homeostasis | Benaroya Research Institute

Researchers at Benaroya Research Institute (BRI) and the University of Washington published findings today in the Journal of Experimental Medicine that illustrate a novel mechanism for regulatory T cells’ (Tregs) role in maintaining balance in a healthy immune system.

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