Breakthrough T1D

Breakthrough T1D

Nonprofit funds T1D research and advocacy

Overview

Company Does Not Provide H1B Sponsorship

What Breakthrough T1D does: It is a global nonprofit organization that funds medical research, advocates for public policy changes, and speeds development of therapies for type 1 diabetes (T1D). How its product works: It does not sell a product; instead it raises funds through donations and events like the Breakthrough T1D Ride, then distributes grants to researchers, supports policy advocacy with governments and regulators, and partners with healthcare groups to improve access to care and therapies. How it differs from competitors: It combines global research funding with public policy advocacy and community fundraising, reinvesting donations into research and program work, with a clear emphasis on accelerating therapy development and improving patient access across multiple regions (notably the US and UK). What its goal is: To eradicate type 1 diabetes by advancing research, shaping policy, and expanding access to treatments and care.

About Breakthrough T1D

Simplify's Rating
Why Breakthrough T1D is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Government & Public Sector

Social Impact

Biotechnology

Healthcare

Company Size

501-1,000

Company Stage

N/A

Total Funding

N/A

Headquarters

Indianapolis, Indiana

Founded

1970

Get referred to Breakthrough T1D

See people who can refer or advise you

Simplify Jobs

Simplify's Take

What believers are saying

  • FDA approved finerenone on September 17, 2026, validating Breakthrough T1D’s kidney-disease strategy.
  • The September 8, 2026 T1D Cures Accelerator expands industry, regulator, and researcher coordination.
  • 2026 partnerships with Greenstone, Encellin, and Sub-Zero deepen funding and therapeutic optionality.

What critics are saying

  • Breakthrough T1D still depends on donations, events, and partner funding for mission execution.
  • Cell therapies remain trapped by donor scarcity and chronic immunosuppression, slowing any cure timeline.
  • If 2026 biomarker and kidney programs stall, Breakthrough T1D loses scientific credibility.

What makes Breakthrough T1D unique

  • Breakthrough T1D pairs advocacy, grantmaking, and clinical-trial convening across 2026 globally.
  • Its T1D Fund and IDDP program directly de-risk cell, biomarker, and therapy development.
  • Few nonprofits influence FDA pathways, like Bayer’s FINE-ONE and HESI’s 2026 accelerator.

Help us improve and share your feedback! Did you find this helpful?

Benefits

Hybrid Work Options

Company News

San Francisco Biotechnology Network
Sep 22nd, 2026
Encellin partners with Breakthrough T1D to advance immune-protected Cell Therapy for Type 1 Diabetes.

Encellin partners with Breakthrough T1D to advance immune-protected Cell Therapy for Type 1 Diabetes. SAN FRANCISCO & NEW YORK & MONTREAL-(BUSINESS WIRE)-Encellin, Inc., a clinical-stage biotechnology company developing Encapsulated Cell Replacement Therapy (ENCRT), today announced a partnership with Breakthrough T1D, the leading global Type 1 Diabetes (T1D) research and advocacy organization, and an award through its Industry Discovery and Development Partnership (IDDP) program to support the advancement of Encellin's ENCRT-103-hPI clinical program in T1D. The new trial (NCT07680673) will br Click here to view original post

Breakthrough T1D
Sep 17th, 2026
Breakthrough T1D celebrates approval of first new treatment for people with type 1 diabetes and chronic kidney disease in 30 years.

Breakthrough T1D celebrates approval of first new treatment for people with type 1 diabetes and chronic kidney disease in 30 years. September 17, 2026 Breakthrough T1D applauds today's approval by the U.S. Food and Drug Administration (FDA) of the drug finerenone (Kerendia(TM)/Firialta(TM) as the first new therapy that can treat chronic kidney disease (CKD) associated with type 1 diabetes (T1D) in 30 years. Finerenone reduces urinary albumin-to-creatinine ratio (UACR) in adults with CKD and T1D, which has been shown to slow CKD progression. It is a once-daily pill that has been approved since 2021 for CKD associated with type 2 diabetes and, since July 2025, for certain adults with heart failure. CKD is one of the most common complications of T1D. Nearly a third of people living with T1D will develop CKD, increasing the risk of both kidney failure and cardiovascular disease. Right now, the treatment options for people with T1D and CKD are limited, and there is a major need for therapies that can address this. Advancing treatments like finerenone that can improve the lives of those living with T1D is core to Breakthrough T1D's mission. "Today there are few treatments available for chronic kidney disease, a common complication of type 1 diabetes. The approval of finerenone is a huge win for the T1D community," said Jonathan Rosen, Ph.D., Breakthrough T1D Research Director. "Breakthrough T1D thanks the FDA for its review and approval and Bayer for their commitment to giving people with T1D a new therapeutic option for chronic kidney disease." Breakthrough T1D collaborated strategically with Bayer to support the FINE-ONE phase 3 clinical trial behind this approval and continues to support multiple clinical trials focused on kidney and heart disease in people with T1D to close the gap in available therapy options.

The Ottomin Group
Aug 31st, 2026
Ottomin Foundation supports Breakthrough T1D with $100,000 donation.

Ottomin Foundation supports Breakthrough T1D with $100,000 donation. 31 August 2026 The Ottomin Foundation is proud to announce a $100,000 donation to Breakthrough T1D, presented at the Night of Champions Gala on Saturday, 29 August 2026. On the night, keynote speakers Jess and Annabelle Kovacs shared their personal experiences and the realities of living with type 1 diabetes (T1D). Held in Sydney, the Night of Champions Gala brought together NSW's T1D community, celebrities, and prominent business and philanthropic leaders for an unforgettable evening that raised $1.1 million to help advance life-changing research for type 1 diabetes. For Ottomin Foundation founders Jennie and Richard Kovacs, the commitment to T1D is driven by a personal mission to improve medical wellbeing and support meaningful progress in the fight against this lifelong autoimmune condition. The Ottomin Foundation also supports Breakthrough T1D's Type1Screen program as a multi-year donor. Type1Screen provides free screening in Australia to help identify early-stage T1D, giving individuals and families the opportunity for earlier monitoring, education, and access to research pathways. The Ottomin Foundation congratulates the Breakthrough T1D team for its leadership in research and advocacy. Through continued collaboration and community support, this work is helping move closer to a future where no one has to live with T1D.

SciRealityPress
Aug 22nd, 2026
IQVIA Clinical Decision Support Tool wins 2026 AI Breakthrough Award for Predictive Modeling Solution of the Year.

IQVIA Clinical Decision Support Tool wins 2026 AI Breakthrough Award for Predictive Modeling Solution of the Year. Published: 22/08/2026 | Last Updated: 23/08/2026 IQVIA Clinical Decision Support Tool has been named winner of the 2026 AI Breakthrough Award for Predictive Modeling Solution of the Year, IQVIA (NYSE:IQV) announced on August 20, 2026. The AI-enabled tool, developed by IQVIA in collaboration with Breakthrough T1D, was recognized for addressing a persistent and costly problem in diabetes care: adults with type 1 diabetes who are misclassified as having type 2 diabetes. IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. The company disclosed the award from Research Triangle Park, North Carolina, describing the recognition as validation of its expanding portfolio of artificial intelligence solutions built for clinical and commercial healthcare use cases. Misclassification between type 1 diabetes (T1D) and type 2 diabetes (T2D) is not a minor coding error. Because the two conditions require different treatment pathways, an incorrect diagnosis can delay the introduction of insulin therapy that T1D patients need, raising the risk of severe and sometimes life-threatening complications such as diabetic ketoacidosis. The IQVIA Clinical Decision Support Tool was built specifically to catch these misclassifications earlier in the care pathway, using predictive modeling to flag patient records that warrant a second look. The tool is powered by IQVIA Healthcare-grade AI(R), a proprietary framework the company says is designed to meet the accuracy, privacy and regulatory standards required for use in real clinical settings rather than experimental pilots. That distinction matters for health systems evaluating whether an AI-enabled tool is ready for production use across large patient populations. IQVIA Clinical Decision Support Tool targets type 1 diabetes misdiagnosis. The scale of the misdiagnosis problem is part of what makes the IQVIA Clinical Decision Support Tool notable. Health systems attempting to identify misclassified T1D patients manually would typically need to review tens of thousands of patient charts to find a small number of true positives, a workload that is rarely practical given constrained clinical staffing and competing priorities. By applying predictive modeling to existing patient data, the IQVIA Clinical Decision Support Tool narrows that universe dramatically before a clinician ever opens a chart. Rather than asking care teams to sift through an entire population, the tool surfaces a short, prioritized list of patients whose records show patterns consistent with a T1D profile despite a T2D diagnosis on file. JobFinder Listing That triage function is the core of why the AI Breakthrough Awards program selected the tool for its Predictive Modeling Solution of the Year category. The program recognizes innovation and performance across the global AI market, and predictive modeling applied to a well-defined clinical gap, rather than a broad or speculative use case, is precisely the kind of measurable outcome the award category is built to highlight. IQVIA Clinical Decision Support Tool delivers measurable screening gains. According to IQVIA, the results reported from deployment of the tool are substantial. The IQVIA Clinical Decision Support Tool cut the overall screening workload by 99.5%, narrowing what would have been a review of roughly 60,000 patient charts down to approximately 300, or about 200 times fewer chart reviews for care teams to complete. Diagnostic yield improved just as sharply. Among patients flagged by the tool, 28% were confirmed or suspected to have type 1 diabetes, compared with a 0.22% baseline rate of T1D confirmation in the broader unscreened population. IQVIA characterizes that shift as an approximately 127-fold increase in diagnostic yield, meaning clinical staff spend their limited chart-review time on patients who are dramatically more likely to actually have the condition the tool is designed to catch. IQVIA said the combined effect of the reduced workload and higher yield is a faster path to correct diagnosis and appropriate treatment for affected patients, which the company links to a lower risk of downstream complications and improved long-term outcomes for people living with undiagnosed or misdiagnosed T1D. Breakthrough T1D partnership shapes IQVIA Clinical Decision Support Tool rollout. The IQVIA Clinical Decision Support Tool was configured in direct partnership with Breakthrough T1D, described in the announcement as the leading global type 1 diabetes research and advocacy nonprofit organization. That collaboration shaped how the tool was built to address specific, persistent gaps in T1D care beyond diagnosis alone, including delayed identification, missed ongoing monitoring, and under-treatment once a correct diagnosis is made. Pairing a disease-specific advocacy organization with a health-data and analytics company is a deliberate design choice. Breakthrough T1D contributes clinical and patient-community context about how T1D actually presents and is missed in practice, while IQVIA contributes the data infrastructure, modeling capability and Healthcare-grade AI(R) framework needed to operationalize that knowledge at population scale across health system records. IQVIA Clinical Decision Support Tool adds to healthcare-grade AI portfolio. The 2026 AI Breakthrough Award adds to what IQVIA describes as a growing portfolio of award-winning AI solutions. IQVIA framed the recognition as reinforcement of its broader strategy of applying Healthcare-grade AI(R) to solve clinical challenges that have resisted simpler technology fixes, positioning predictive, clinically embedded tools like this one as a template for future product development. IQVIA's portfolio of solutions is powered by IQVIA Connected Intelligence(TM), which the company says combines high-quality health data, Healthcare-grade AI(R), advanced analytics and deep domain expertise into actionable insights for biotech, medical device and pharmaceutical companies, medical researchers, government agencies, payers and other healthcare stakeholders. With approximately 94,000 employees operating in over 100 countries, IQVIA positions itself as a company built to deploy tools like the Clinical Decision Support Tool at the scale global health systems require, while maintaining what it describes as best-in-class approaches to patient privacy, regulatory compliance and patient safety throughout the AI development lifecycle. IQVIA, led by chief executive officer Ari Bousbib and headquartered in Durham, North Carolina, reported revenues of $16.3 billion for 2025. The company's decision to highlight the IQVIA Clinical Decision Support Tool win alongside its other 2026 disclosures reflects a broader pattern: IQVIA has used recent announcements, including an Everest Group ranking as the top-scored pharmaceutical technology provider for 2026 and a strategic collaboration with Medera on cardiac gene therapy research, to underscore how its data and AI capabilities extend across clinical development, commercial insight and now direct point-of-care decision support.

GenomeWeb
Aug 21st, 2026
Greenstone bio wins $1.2M Breakthrough T1D grant for stem cell-based type 1 diabetes research.

Greenstone bio wins $1.2M Breakthrough T1D grant for stem cell-based type 1 diabetes research. NEW YORK - Advocacy organization Breakthrough T1D said this week that it has awarded a $1.2 million grant to Greenstone Biosciences to study biologic variations in type 1 diabetes (T1D) patients. Get the full story with GenomeWeb Premium. Only $95 for the first 90 days. Full site access Interest-based email alerts Premium Access - Trial Offer $95.00 for 3 month Already a GenomeWeb member? LoginLogin

Recently Posted Jobs

Sign up to get curated job recommendations

There are no jobs for Breakthrough T1D right now.

Find jobs on Simplify and start your career today

We update Breakthrough T1D's jobs every few hours, so check again soon! Browse all jobs →