CRISPR Therapeutics

CRISPR Therapeutics

Develops gene-editing therapies using CRISPR

Overview

CRISPR Therapeutics develops gene-editing medicines using CRISPR/Cas9 to treat serious diseases. It edits genes in human cells, either ex vivo or in vivo, to correct disease-causing mutations, focusing on sickle cell disease, cancer, and other genetically defined conditions. The company supports its pipeline through partnerships and licensing in addition to internal R&D and clinical work, rather than relying solely on in-house development. Its goal is to deliver durable, disease-modifying therapies that meet unmet medical needs for patients worldwide through a global biopharmaceutical strategy.

About CRISPR Therapeutics

Simplify's Rating
Why CRISPR Therapeutics is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Biotechnology

Healthcare

Company Size

201-500

Company Stage

IPO

Headquarters

Switzerland

Founded

2013

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Simplify's Take

What believers are saying

  • Q2 2026 CASGEVY revenue hit $76 million, up 151% year over year.
  • July 2026 FDA approval added about 5,500 eligible U.S. patients under age 12.
  • June 2026 cash reached $2.36 billion, funding operations while Phase 1 programs advance.

What critics are saying

  • Q1 2026 non-CASGEVY revenue was only $1.5 million, showing brutal concentration.
  • Vertex controls CASGEVY commercialization; slow center onboarding can keep uptake weak through 2027.
  • CTX112, CTX340, and CTX460 face clinical failure risk, leaving CRSP dependent on one drug.

What makes CRISPR Therapeutics unique

  • CASGEVY is the first approved CRISPR/Cas9 therapy, now cleared for children two and older.
  • CRISPR controls wholly owned in vivo and CAR-T programs, unlike CASGEVY's Vertex partnership.
  • June 2026 FDA clearance for CTX340 and CTX460 broadens CRISPR beyond hemoglobinopathies.

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Funding

Total Funding

$1.1B

Above

Industry Average

Funded Over

6 Rounds

Post IPO Convertible funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Convertible Funding Comparison
Coming Soon

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Health Savings Account/Flexible Spending Account

Unlimited Paid Time Off

Flexible Work Hours

Hybrid Work Options

Stock Options

401(k) Retirement Plan

Wellness Program

Mental Health Support

Gym Membership

Phone/Internet Stipend

Home Office Stipend

Conference Attendance Budget

Professional Development Budget

Family Planning Benefits

Fertility Treatment Support

Adoption Assistance

Parental Leave

Paid Vacation

Paid Holidays

Relocation Assistance

Sabbatical Leave

Paid Sick Leave

Employee Discounts

Employee Referral Bonus

Tuition Reimbursement

Professional Certification Support

Mentorship Program

Training Programs

Meal Benefits

Commuter Benefits

Legal Services

Research Collaboration Benefits

Stock Price

Growth & Insights and Company News

Headcount

6 month growth

1%

1 year growth

0%

2 year growth

2%
Yahoo Finance
Aug 3rd, 2026
CRISPR shares rise as gene therapy CASGEVY hits $76M in Q2, pipeline updates planned

CRISPR Therapeutics outlined a busy second-half pipeline and reported strong quarterly growth in its marketed gene therapy. Shares rose 1.4% in after-hours trading on Monday. Updates are expected on a gene-editing treatment for severe high triglycerides and hard-to-control cholesterol, with results to be presented at a major heart conference on 28 August. More data is also anticipated for a blood-clotting therapy and an immune-cell treatment being tested in autoimmune diseases and blood cancers. CASGEVY, the gene therapy for sickle cell disease and a related blood disorder, generated $76 million in second-quarter revenue, a 78% increase from the prior quarter. The FDA recently approved it for children as young as two. Net loss narrowed to $91.2 million from $208.5 million a year earlier.

Yahoo Finance
Aug 3rd, 2026
CRISPR Therapeutics reports $76M CASGEVY revenue in Q2 2026, up 151% year-over-year

CRISPR Therapeutics reported second quarter 2026 financial results, with CASGEVY generating $76 million in revenue, representing 78% growth quarter-over-quarter and 151% growth year-over-year. The FDA recently approved CASGEVY for children as young as 2 years with sickle cell disease or transfusion-dependent beta thalassemia, achieved in 53 days post-filing. This approval makes approximately 5,500 additional patients eligible for treatment. The company initiated Phase 1 clinical trials for CTX340 for refractory hypertension and CTX460 for alpha-1 antitrypsin deficiency, expanding its in vivo pipeline. Vertex secured reimbursement for CASGEVY in Germany for eligible patients aged 12 and older. CASGEVY is now approved in 39 countries across North America, Europe, and the Middle East.

Yahoo Finance
Jul 6th, 2026
CRISPR Therapeutics vs. Viking Therapeutics: Which Healthcare Stock Is a Better Buy in 2026?

CRISPR Therapeutics vs. Viking Therapeutics: Which Healthcare Stock Is a Better Buy in 2026? Erin Kennedy, The Motley Fool

Yahoo Finance
Jul 3rd, 2026
CRISPR Therapeutics rises 11.3% on Russell growth index inclusion despite $100M quarterly losses

CRISPR Therapeutics rose 11.3% following its addition to several Russell growth indices in late June 2026, including the Russell 2000 Growth, 2500 Growth and 3000 Growth benchmarks. The inclusion increases visibility among benchmarked funds but doesn't alter the company's fundamental profile. The gene-editing company generates only a few million dollars in annual revenue against hundreds of millions in losses, with value concentrated in its clinical pipeline rather than current operations. Its allogeneic CAR T and in vivo editing programmes face ongoing clinical and regulatory milestones. Whilst index inclusion may support liquidity and trading, it doesn't reduce execution, funding or trial risks. Simply Wall St community members' fair value estimates range from $67.82 to $208.83, reflecting divergent views on the loss-making company's prospects.

Yahoo Finance
Jun 18th, 2026
CRISPR Therapeutics reports $1.5M revenue despite $2.4B cash reserves amid slow CASGEVY adoption

CRISPR Therapeutics has experienced significant stock volatility this year as investors grapple with its transition from clinical to commercial stage. The company's gene-editing therapy CASGEVY, developed with Vertex Pharmaceuticals and approved in late 2023 for sickle cell disease, generated only $1.46 million in revenue during Q1 2026, whilst posting a $122.9 million net loss. Commercial adoption faces challenges, as gene-editing treatments require specialised centres, complex preparations and lengthy approval processes. However, CRISPR maintains a strong balance sheet with approximately $2.4 billion in cash and marketable securities. The company's investigational CAR-T therapy CTX112 has attracted attention as a potential "off-the-shelf" treatment that could be produced at scale, lowering costs and shortening treatment timelines compared to traditional personalised therapies.

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