Citrine Informatics

Citrine Informatics

AI-driven materials R&D platform

Overview

Citrine Informatics provides an AI-powered SaaS platform for materials and chemicals R&D. It offers tools like DataManager for materials data management, VirtualLab for simulations and property predictions, and Catalyst for optimizing development workflows, all available via subscriptions with optional professional services. Enterprises use the platform to organize data, run AI-driven simulations, and speed up experiments to reduce costs and improve product performance. The goal is to help product developers, engineers, and business leaders accelerate R&D and achieve faster, more cost-effective innovation across industries such as manufacturing, automotive, aerospace, and consumer goods.

About Citrine Informatics

Simplify's Rating
Why Citrine Informatics is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

Industrial & Manufacturing

Enterprise Software

AI & Machine Learning

Company Size

51-200

Company Stage

Late Stage VC

Total Funding

$69.1M

Headquarters

Redwood City, California

Founded

2013

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Simplify's Take

What believers are saying

  • Citrine's July 2026 benchmarks claim Apex matches tuned models 95% of the time.
  • Forum Rathenau's September 2026 bootcamp gives Citrine visibility across Germany's green deep-tech ecosystem.
  • Recurring customer proof from Avery Dennison, Gebrüder Dorfner, and Sion Power supports sales.

What critics are saying

  • No funding followed the September 2023 round; growth now depends on operating cash.
  • Radical AI, CuspAI, and Osium AI commoditize materials AI and squeeze Citrine's pricing power.
  • If Catalyst and Apex underdeliver, customers keep spreadsheets and consultants instead of platform subscriptions.

What makes Citrine Informatics unique

  • Citrine's July 2026 Catalyst and Apex compress experiment design from goals to minutes.
  • Perstorp chose Citrine in April 2026 for alkyd emulsions, proving mainstream chemicals adoption.
  • ANZAPLAN uses Citrine to optimize mineral processing across ore chemistry and regional economics.

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Funding

Total Funding

$69.1M

Below

Industry Average

Funded Over

7 Rounds

Late VC funding comparison data is currently unavailable. We're working to provide this information soon!
Late VC Funding Comparison
Coming Soon

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Health Savings Account/Flexible Spending Account

Unlimited Paid Time Off

Flexible Work Hours

Paid Holidays

401(k) Company Match

Paid Parental Leave

Company Equity

Phone/Internet Stipend

Professional Development Budget

Mentorship Program

Growth & Insights and Company News

Headcount

6 month growth

↓ -2%

1 year growth

↑ 0%

2 year growth

↓ -5%
AZoM
Sep 2nd, 2026
Forum Rathenau and Citrine Informatics partner to accelerate Germany's Green Deep Tech ecosystem.

Forum Rathenau and Citrine Informatics partner to accelerate Germany's Green Deep Tech ecosystem. BITTERFELD-WOLFEN, Germany and REDWOOD CITY, Calif., [DATE] - Forum Rathenau and Citrine Informatics today announced a collaboration supporting Scale New Chemistry, a Green Deep Tech Bootcamp designed to transform industrial challenges into scalable solutions and new businesses for the chemical and materials industries. The initiative brings together regional companies, researchers, entrepreneurs, and industry experts to address practical challenges in areas including CO[2] reduction, circular use of resources, sustainable raw materials, and new chemical-industry business models. Forum Rathenau's approach begins with concrete needs identified by industry and supports interdisciplinary teams in developing technically and commercially viable solutions. Through the collaboration, Citrine will provide participating teams with access to its AI-powered materials informatics platform, as well as training and continuous technical support. The platform will serve as the digital backbone of the program, giving teams a shared environment in which to structure experimental data, develop predictive models, optimize research decisions, and retain knowledge throughout the development process. Because the Citrine Platform is material agnostic, it can seamlessly support startups working across different chemical and material classes. Teams developing polymers, catalysts, battery materials, composites, metals, or other advanced technologies can use the same digital infrastructure while configuring their workflows around their own scientific challenges. This allows the program to support a diverse portfolio of companies without creating separate digital systems for every application. "In the chemical industry in particular, the path from a forward-looking idea to a marketable product is often a long one. Between laboratory validation and industrial application lies the challenging pilot-scale phase, during which many promising approaches get stuck due to a lack of capital, infrastructure, and access to industrial partners. This is exactly where 'Scale New Chemistry' comes in: The program supports startups at this critical juncture and connects them with the expertise, facilities, and market knowledge available in the Chemical Triangle," says Professor Ralf Wehrspohn, Chairman of the Board of Forum Rathenau. The region offers ideal conditions for this: established chemical sites with the necessary infrastructure, a well-connected industrial landscape, and a strong research base. "With the two projects 'Create' and 'Scale New Chemistry,' Forum Rathenau has introduced and further developed a new format in the region - one that, in my view, has long been missing. Bringing together startups and established chemical companies around common topics has the potential to be a key element in a successful transformation toward a carbon-neutral circular economy," says Patrice Heine, Managing Director of the Bitterfeld-Wolfen Chemical Park and Board Member of Forum Rathenau, regarding the program. Citrine will support participating teams from initial technical validation and onboarding through iterative AI-enabled development sprints. The work will help teams assess their data, define suitable modeling tasks, test material hypotheses, and translate technical results into decision-ready information for founders, mentors, and industrial partners. "Innovation happens fastest when scientists, entrepreneurs, and industrial partners can learn from data together," said Greg Mulholland, CEO of Citrine Informatics. "Our mission is to enable a greener, more efficient world by accelerating the development and deployment of next-generation materials and chemicals. By providing the digital backbone for Scale New Chemistry, we can help startups make smarter R&D decisions, reduce time-consuming trial-and-error experimentation, and bring sustainable technologies with real environmental and economic impact to market faster." The collaboration builds on Forum Rathenau's work to connect industry, science, startups, and regional infrastructure in support of a circular economy. Previous bootcamp teams have worked on challenges such as recovering useful materials from industrial by-products, reducing the energy demand of separation processes, improving battery insulation, and creating new local value chains from waste streams. By combining this physical and entrepreneurial ecosystem with a common AI-enabled digital infrastructure, Forum Rathenau and Citrine aim to shorten development cycles, reduce technical risk, and make advanced materials development more accessible to emerging companies. The partnership is intended to benefit not only the participating teams, but also the wider startup and industrial ecosystem. Reusable data structures, validated workflows, and transferable best practices can provide a scalable foundation for future cohorts and help more sustainable chemistry innovations move from research into commercial application. About Forum Rathenau. Based in Bitterfeld-Wolfen, Forum Rathenau e.V. is driving the transformation process in the Central German Mining Region. Founded in 2019, the project promotes innovations in the carbon cycle economy. Since 2023, it has been funded as part of the STARK Program of the Federal Ministry for Economic Affairs and Energy. On the path toward a post-fossil, sustainable carbon competence cluster in Saxony-Anhalt, the research staff focus on school education, develop lifelong learning formats, promote corporate transformations and start-ups, and use communication formats to highlight the opportunities offered by the post-fossil circular economy. About Citrine Informatics. Citrine Informatics provides an AI platform purpose-built for materials and chemicals product development. Citrine helps technical teams use data, domain expertise, and artificial intelligence to accelerate materials design, formulation, process optimization, and manufacturing innovation.

Citrine Informatics
Mar 27th, 2026
Citrine Informatics and ANZAPLAN collaborate to accelerate economically optimized mineral processing using AI.

Citrine Informatics and ANZAPLAN collaborate to accelerate economically optimized mineral processing using AI. Partnership demonstrates how AI-driven process design can identify the most economical processing routes by integrating ore chemistry, process options, and regional economics. REDWOOD CITY, Calif. and HIRSCHAU, Germany - Citrine Informatics, the leader in AI for materials and chemicals innovation, and ANZAPLAN GmbH, a global specialist in critical minerals process development, today announced a collaboration using artificial intelligence to accelerate the design of economically optimized processing routes for mineral resources. ANZAPLAN is leveraging Citrine's AI platform to analyze complex interactions between ore composition, processing pathways, and regional economic factors to identify optimal process flowsheets earlier in development. The approach helps determine which processing routes are most viable by considering not only the purity and performance of the final product but also location-specific cost structures and the mineralogical impurities present in different ore deposits. Traditional process development typically evaluates technical performance first and only later incorporates economic considerations, often leading to long iteration cycles and suboptimal outcomes. By contrast, the AI-driven approach simultaneously evaluates material characteristics, processing methods, and location-specific economics to identify the most economically advantageous process from the start. By combining ANZAPLAN's extensive domain expertise and process data with Citrine's materials AI capabilities, ANZAPLAN are supporting customers accelerate feasibility studies, reduce experimental effort, and move faster toward scalable production. "Materials innovation today requires navigating an enormous landscape of possibilities across chemistry, manufacturing, cost, and supply," said Greg Mulholland, CEO of Citrine Informatics. "This collaboration shows how AI can unlock faster, smarter process development across the materials and chemical industries." "Process development for mineral resources is inherently complex because the optimal solution depends on many interacting variables," said Reiner Haus, Managing Director at ANZAPLAN GmbH. "With AI, we can simultaneously consider feed material properties, process options, and regional economic factors to design flowsheets tailored to each specific deposit and project location. This allows us to move faster, reduce testing effort, and deliver more robust and economically optimized solutions for our customers." The collaboration highlights a broader shift toward data-driven process design in the materials and chemicals industries. By applying AI companies can rapidly explore alternative processing routes, quantify tradeoffs, and identify the most economically and technically viable paths to production. About Citrine Informatics. Citrine Informatics provides an AI platform that accelerates materials and chemicals development by enabling organizations to capture experimental data, build predictive models, and optimize formulations and processes. Leading companies across chemicals, advanced materials, and manufacturing use Citrine's platform to reduce development timelines, improve product performance, and bring innovations to market faster. About ANZAPLAN. ANZAPLAN, part of the Dorfner Group, is a leading engineering and consulting company specializing in industrial minerals, advanced materials, and process development. The company provides laboratory services, pilot testing, and process engineering expertise to support resource projects and materials innovation worldwide.

U.S. Securities and Exchange Commission
Apr 18th, 2025
SEC FORM D

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.The reader should not assume that the information is accurate and complete.

U.S. Securities and Exchange Commission
Apr 16th, 2025
SEC FORM D

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.The reader should not assume that the information is accurate and complete.

America’s Seed Fund powered by NSF
Apr 16th, 2025
Award History Details | NSF SBIR

National Science Foundation 2415 Eisenhower Ave. Alexandria, VA 22314 USA

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