Epinomics

Epinomics

ATAC-seq based epigenomic analytics platform

Overview

Epinomics provided an epigenomics platform that uses ATAC-seq to map chromatin accessibility and gene regulation from a small number of cells, supporting drug development and biomarker discovery. It combines this high-sensitivity epigenomic assay with a data analytics engine to interpret regulatory patterns and predict responses in areas like immuno-oncology. The company stood out by delivering cell-efficient, high-resolution epigenetic insights through collaborations with pharma, biotech, and academia. Its goal was to speed therapeutic development and biomarker discovery by turning dynamic epigenetic data into actionable insights, and its team/technology were later integrated into 10x Genomics’ Chromium Single Cell ATAC Solution.

About Epinomics

Simplify's Rating
Why Epinomics is rated
C+
Rated C on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

Biotechnology

Healthcare

Company Size

1-10

Company Stage

N/A

Total Funding

N/A

Headquarters

San Francisco, California

Founded

2013

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Simplify's Take

What believers are saying

  • 10x updated Epi ATAC documentation on September 17, 2026, showing active commercialization.
  • 10x won a Delaware jury verdict against Parse on August 28, 2026.
  • Chromatin accessibility remains embedded in 10x’s Chromium platform, sustaining recurring reagent demand.

What critics are saying

  • Epinomics no longer operates independently; 10x Genomics absorbed it in August 2018.
  • 10x faces fierce competition from Parse Biosciences and Qiagen in single-cell sequencing.
  • If 10x deprioritizes ATAC, Epinomics’ technology becomes a niche legacy product.

What makes Epinomics unique

  • Epinomics’ ATAC-seq IP became 10x Genomics’ Chromium Single Cell ATAC platform in 2018.
  • Howard Chang and William Greenleaf invented ATAC-seq, giving Epinomics deep scientific credibility.
  • Its small-sample chromatin accessibility workflow differentiated it from older bulk epigenomics assays.

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