Epinomics

Epinomics

Provides ATAC-seq based epigenomic analytics

Overview

Epinomics offered an epigenomics platform built around ATAC-seq, a method for mapping which parts of the genome are open and actively regulating genes. Its workflow combines the ATAC-seq lab steps with a data analytics engine to turn epigenetic data into insights about gene regulation, disease, and potential treatment responses. The platform works well with small numbers of cells, enabling high-resolution views of chromatin accessibility that support biomarker discovery and immuno-oncology research. After being acquired by 10x Genomics in 2018, its technology and team were integrated into 10x’s Chromium Single Cell ATAC solution to advance their product portfolio. The goal is to help researchers accelerate drug discovery and personalized medicine by decoding how epigenetic changes influence disease and therapy outcomes.

About Epinomics

Simplify's Rating
Why Epinomics is rated
D+
Rated D+ on Competitive Edge
Rated D+ on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

Biotechnology

Company Size

1-10

Company Stage

N/A

Total Funding

N/A

Headquarters

San Francisco, California

Founded

2013

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Simplify's Take

What believers are saying

  • 10x Genomics kept 2026 revenue guidance at $600 million to $625 million.
  • Bruker will pay 10x $68 million plus ongoing royalties through 2026.
  • 10x launched Multiome ATAC plus Gene Expression, commercializing Epinomics' core thesis.

What critics are saying

  • On August 19, 2026, the Federal Circuit upheld PTAB wins for Parse Biosciences.
  • 10x's patent-enforcement model faces Element Biosciences and Curio retaliation in 2026.
  • Epinomics no longer exists standalone, so talent and strategy live inside 10x Genomics.

What makes Epinomics unique

  • Epinomics' ATAC-seq IP seeded 10x Genomics' Chromium Single Cell ATAC products.
  • Stanford founders Howard Chang and William Greenleaf gave Epinomics elite epigenomics credibility.
  • Its technology mapped chromatin accessibility from tiny samples, enabling single-cell epigenetics workflows.

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