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Erasca

Clinical-stage oncology company targeting RAS/MAPK pathway

Overview

Erasca is a clinical-stage precision oncology company focused on stopping the RAS/MAPK signaling pathway, a major driver in many cancers. Its products aim to block this pathway across multiple modalities to treat a wide range of tumors that rely on RAS/MAPK signaling. The company distinguishes itself by pursuing a comprehensive shutdown of the pathway through diverse therapeutic approaches, targeting cancer patients worldwide and seeking to bring multiple therapeutic programs to approval and commercialization. Its ultimate goal is to eradicate cancer and improve outcomes for millions of patients affected by RAS/MAPK-driven tumors.

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About Erasca

Simplify's Rating
Why Erasca is rated
C+
Rated B on Competitive Edge
Rated B on Growth Potential
Rated D+ on Differentiation

Industries

BiotechnologyHealthcare

Company Size

51-200

Company Stage

IPO

Headquarters

San Diego, CA

Founded

2018

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What believers are saying

  • Cash reached $948 million on September 30, 2026, funding 2027 trial launches.
  • November 12, 2026 results highlighted three potentially registration-enabling trials in pancreatic and lung cancers.
  • ERAS-0015 showed 57% response in KRAS G12X pancreatic cancer, supporting expansion.

What critics are saying

  • Revolution Medicines sued April 27, 2026 over patent infringement and trade secrets.
  • The April 27, 2026 ERAS-0015 death and pneumonitis concerns threaten registrational timelines.
  • A failed ERAS-0015 Phase 3 would collapse Erasca's single-program valuation story.

What makes Erasca unique

  • Erasca’s pan-RAS strategy attacks KRAS, RAF, and downstream signaling across multiple tumor types.
  • ERAS-0015 earned FDA Fast Track on August 2026 for metastatic pancreatic adenocarcinoma.
  • Charles Fuchs joined August 10, 2026, strengthening R&D with GI oncology execution.

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Funding

Total Funding

$1.6B

Above

Industry Average

Funded Over

9 Rounds

Notable Investors:
Post IPO Equity funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Equity Funding Comparison Coming Soon

Benefits

  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • Disability Insurance
  • Health Savings Account/Flexible Spending Account
  • Life Insurance
  • Pet Insurance
  • Paid Vacation
  • Paid Holidays
  • Paid Sick Leave
  • 401(k) Retirement Plan
  • Company Equity

Stock Price

Growth & Insights and Company News

6 month growth

0%

1 year growth

-2%

2 year growth

0%
Yahoo Finance
Nov 12th, 2026
Erasca wins FDA Fast Track for pancreatic cancer drug, holds $948M in cash

Erasca, a clinical-stage cancer drug developer, said the US Food and Drug Administration (FDA) granted Fast Track Designation to its drug ERAS-0015 for metastatic pancreatic adenocarcinoma. The company is advancing toward three potentially registration-enabling trials in pancreatic and lung cancers. Cash and marketable securities stood at $947.8 million on September 30, 2026, up from $341.8 million at the end of 2025. In July, Erasca raised about $632.5 million in an upsized public offering. Net loss for the third quarter widened to $51.3 million from $30.6 million a year earlier. Research and development expenses rose to $47.2 million from $22.5 million. Erasca expects preliminary data for ERAS-4001 in the second half of 2026 and further ERAS-0015 data in the first half of 2027.

Yahoo Finance
Nov 12th, 2026
Erasca and Tango begin Phase 1/2 pancreatic and lung cancer combination trial

Tango Therapeutics and Erasca have started a Phase 1/2 trial combining Tango's vopimetostat with Erasca's ERAS-0015. The study targets MTAP-deleted pancreatic cancer and RAS-mutant non-small cell lung cancer. It will test dose, safety, pharmacokinetics, and early antitumour activity. The deal extends Erasca's pan-RAS program into genetically defined MTAP-deleted tumours without requiring it to fully fund a second drug. Erasca's July 2026 equity raise extended its cash runway into the second half of 2028. Key risks remain ERAS-0015 safety data, past pneumonitis concerns, and legal and intellectual property issues.

Associated Press
Oct 23rd, 2026
Erasca shares fall 9.95% after COO exit as SBS Law investigates investor claims

Schall, Brown & Schwartz LLP (SBS), a shareholder rights litigation firm, is investigating whether Erasca, Inc. (NASDAQ: ERAS) issued false or misleading statements, or failed to disclose information important to investors. In a US Securities and Exchange Commission (SEC) filing on October 16, 2026, Erasca said the employment of chief operating officer Nicholas Chetwyn will end on November 2, 2026. The company said the change would "realign its leadership responsibilities to support the development and potential commercialization of its RAS-targeting programs." Erasca shares fell 9.95% that day. SBS is encouraging affected shareholders to contact the firm to discuss their rights free of charge.

Finimize
Oct 16th, 2026
Biotech stocks stumbled as leadership and regulators made waves.

Biotech stocks stumbled as leadership and regulators made waves. IBB slid 2.6% while Erasca's COO exit and Omeros' EU setback added to a choppy day for healthcare names. about 1 hour ago - 2 mins What's going on here? Biotech stocks had a rough Friday: the iShares Biotechnology ETF (IBB) fell 2.6% as leadership changes and trial-and-regulator news sent a few single names sharply higher and lower. What does this mean? Broader healthcare looked relatively calm, with the NYSE Healthcare Index up 0.1% and the Health Care Select Sector SPDR Fund (XLV) down 0.3%, but biotech is unusually sensitive to company-specific updates. Erasca sank more than 9% after saying its chief operating officer, Nicholas Chetwyn, will leave effective November 2nd as the company streamlines reporting lines. Omeros slid nearly 15% after the European Medicines Agency's Committee for Medicinal Products for Hu... Keep reading for free. This content is free, but you must be logged in to continue reading. Already have an account?

GlobeNewswire
Oct 9th, 2026
Johnson Fistel, PLLP investigates claims on behalf of long-term shareholders of Erasca, Inc. (ERAS), DICK'S Sporting Goods, Inc. (DKS), Corcept Therapeutics Incorporated (CORT), and Charter Communi...

Johnson Fistel, PLLP investigates claims on behalf of long-term shareholders of Erasca, Inc. (ERAS), DICK'S Sporting Goods, Inc. (DKS), Corcept Therapeutics Incorporated (CORT), and Charter Communications, Inc. (CHTR). SAN DIEGO, Oct. 09, 2026 (GLOBE NEWSWIRE) - Johnson Fistel, PLLP is investigating potential claims on behalf of current, long-term shareholders of Erasca, Inc. (NASDAQ: ERAS), DICK'S Sporting Goods, Inc. (NYSE: DKS), Corcept Therapeutics Incorporated (NASDAQ: CORT), and Charter Communications, Inc. (NASDAQ: CHTR) against certain of their officers and directors for alleged breaches of fiduciary duty. Shareholders who purchased shares before the dates listed below and have continuously held those shares may have standing to seek corporate governance reforms and the return of funds to the company. For a named plaintiff, the firm may also seek a reasonable incentive award, subject to court approval. Representation is on a contingency-fee basis, with no legal fees or expenses payable by participating shareholders. Erasca, Inc. (NASDAQ: ERAS) If you purchased Erasca shares before January 14, 2025, and have continuously held those shares, you may have standing to seek corporate governance reforms at Erasca, including improvements to clinical-development oversight, intellectual-property risk management, disclosure practices, and executive accountability. To learn more, visit https://www.johnsonfistel.com/investigations/erasca/ or contact Johnson Fistel, PLLP at [email protected] or (619) 814-4471. There is no cost or obligation. Complaint Allegations A previously filed securities complaint concerns Erasca's disclosures about its drug candidate ERAS-0015. According to the complaint, Erasca disclosed on April 27, 2026, that Revolution Medicines had sent a letter raising patent-infringement and trade-secret allegations and challenging public comparisons between ERAS-0015 and Revolution Medicines' RMC-6236. The complaint also addresses subsequent preliminary clinical results, a reported patient death, and Erasca's acknowledgment that comparisons with other drug candidates relied on inherently limited cross-study analyses rather than direct, head-to-head trials. DICK'S Sporting Goods, Inc. (NYSE: DKS) If you purchased DICK'S Sporting Goods shares before May 25, 2022, and have continuously held those shares, you may have standing to seek corporate governance reforms at DICK'S, including improvements to inventory management, demand forecasting, disclosure controls, and executive oversight. To learn more, visit https://www.johnsonfistel.com/investigations/dicks-sporting-goods/ or contact Johnson Fistel, PLLP at [email protected] or (619) 814-4471. There is no cost or obligation. Complaint Allegations A previously filed securities class action complaint alleges that DICK'S and certain executives misrepresented demand and inventory conditions in the Company's outdoor segment. Specifically, demand allegedly weakened more rapidly than disclosed, leaving the Company with excess merchandise. The complaint further alleges that operational improvements promoted by defendants were insufficient to prevent inventory liquidation from reducing profitability. Consequently, defendants' favorable statements about the Company's business and outlook allegedly lacked a reasonable basis. Corcept Therapeutics Incorporated (NASDAQ: CORT) If you purchased Corcept shares before October 31, 2024, and have continuously held those shares, you may have standing to seek corporate governance reforms at Corcept, including improvements to regulatory-risk oversight, clinical-data disclosures, internal controls, and executive accountability. To learn more, visit https://www.johnsonfistel.com/investigations/corcept-therapeutics-inc-2/or contact Johnson Fistel, PLLP at [email protected] or (619) 814-4471. There is no cost or obligation. Complaint Allegations A previously filed securities class action complaint alleges that Corcept and certain executives misled investors about the likelihood of FDA approval of relacorilant for patients with hypercortisolism. Defendants allegedly expressed confidence in the application while failing to disclose repeated FDA concerns about whether the supporting clinical evidence was adequate. On December 31, 2025, Corcept announced that the FDA had issued a Complete Response Letter requiring additional evidence of effectiveness before it could reach a favorable benefit-risk assessment. The complaint alleges that this disclosure revealed previously undisclosed regulatory risks. Charter Communications, Inc. (NASDAQ: CHTR) If you purchased Charter shares before July 26, 2024, and have continuously held those shares, you may have standing to seek corporate governance reforms at Charter, including improvements to subscriber-trend reporting, financial forecasting, disclosure controls, and executive oversight. To learn more, visit https://www.johnsonfistel.com/investigations/charter-communications-inc-nasdaq-chtr/ or contact Johnson Fistel, PLLP at [email protected] or (619) 814-4471. There is no cost or obligation. Complaint Allegations A previously filed securities class action complaint alleges that Charter and certain executives misled investors about the business consequences of the termination of the Federal Communications Commission's Affordable Connectivity Program ("ACP"). According to the complaint, defendants understated the resulting pressure on Internet subscriber trends, revenue, and sustainable earnings growth. The complaint further alleges that these conditions undermined the basis for defendants' optimistic statements about operations and long-term EBITDA growth, with subsequent disappointing results allegedly exposing the earlier misrepresentations. About Johnson Fistel, PLLP | Top Law Firm, Securities Fraud, Investors Rights: Johnson Fistel, PLLP is a nationally recognized shareholder rights law firm with offices in California, New York, Georgia, Idaho, and Colorado. The firm represents individual and institutional investors in shareholder derivative and securities class action lawsuits. We also extend our services to foreign investors who have purchased on U.S. exchanges. For more information about the firm and how we may be able to help you recover your losses, please visit https://www.johnsonfistel.com. Achievements: In 2024, Johnson Fistel was ranked in the Top 10 Plaintiff Law Firms by ISS Securities Class Action Services. The firm has recovered approximately $90,725,000 for aggrieved clients in cases where it served as lead or co-lead counsel, marking the eighth time it has been recognized among the top U.S. plaintiffs' securities law firms. Johnson Fistel, PLLP 501 W. Broadway, Suite 800 San Diego, CA 92101 James Baker, Investor Relations, or Frank J. Johnson, Esq. (619) 814-4471 [email protected] or [email protected]

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