Fabric Genomics

Fabric Genomics

AI-driven SaaS for genomic analysis

Overview

Fabric Genomics provides AI-powered genomic analysis and reporting for hospitals, research institutions, and diagnostic labs through a software-as-a-service platform. It analyzes Next-Generation Sequencing data, including whole genomes, exomes, and gene panels, and uses the Fabric GEM AI to interpret variants and generate clinical reports, with automated reanalysis to revisit undiagnosed cases over time. The service differentiates itself with AI-driven interpretation, support for multiple NGS types, and continuous reanalysis delivered via a scalable SaaS model. The goal is to help clinicians diagnose genetic conditions more quickly and accurately while lowering the time and cost of genomic testing.

About Fabric Genomics

Simplify's Rating
Why Fabric Genomics is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

Enterprise Software

AI & Machine Learning

Healthcare

Company Size

11-50

Company Stage

Series B

Total Funding

$29.8M

Headquarters

San Francisco, California

Founded

2009

Simplify Jobs

Simplify's Take

What believers are saying

  • GeneDx acquisition in April 2025 boosts clinical expertise and global scale.
  • Partnerships with Intermountain and Plumcare expand NICU and newborn screening.
  • Software deals with Oxford Nanopore and DNAnexus enhance long-read compatibility.

What critics are saying

  • GeneDx integration dilutes Fabric's autonomous AI innovation within 6-12 months.
  • Illumina-Veracyte bundles displace Fabric's standalone SaaS in hospitals.
  • CMS reimbursement caps compress NICU WGS margins in 12-18 months.

What makes Fabric Genomics unique

  • Fabric GEM AI algorithm automates reanalysis of undiagnosed genomic cases.
  • Selected as primary interpreter for UK's 100,000 Genomes Project in 2015.
  • Achieves 54% causative yields in whole genome analysis for top organizations.

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Funding

Total Funding

$29.8M

Below

Industry Average

Funded Over

2 Rounds

Series B funding is typically for startups that have proven their business model and need more funding to expand rapidly—often by entering new markets or adding more products. Investors are usually venture capital firms that specialize in later-stage investments.
Series B Funding Comparison
Below Average

Industry standards

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Substack
$100M
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Benefits

Competitive compensation

Health benefits and coverage

PTO

Parental leave

Growth & Insights and Company News

Headcount

6 month growth

3%

1 year growth

3%

2 year growth

3%
360Dx
Jun 23rd, 2025
Galatea Bio, Fabric Genomics Partner to Develop Genetic Disease Risk Assays

Galatea Bio, Fabric Genomics partner to develop genetic disease risk assays.

Business Wire
May 8th, 2025
GeneDx Announces Completion of Fabric Genomics Acquisition

GeneDx (Nasdaq: WGS) today announced the successful completion of its acquisition of Fabric Genomics, a pioneer in AI-powered genomic interpretation.

Stock Titan
May 7th, 2025
GeneDx Completes Fabric Genomics Acquisition

GeneDx has completed its acquisition of Fabric Genomics, enhancing its capabilities in genomic medicine by integrating Fabric's AI-powered genomic interpretation. This merger aims to improve global healthcare by offering centralized and decentralized genomic insights, facilitating earlier and more accurate diagnoses. Fabric Genomics will continue as a subsidiary of GeneDx, leveraging GeneDx's clinical expertise and Fabric's advanced technology to set new standards in genomic diagnostics.

360Dx
Apr 16th, 2025
GeneDx to Acquire Fabric Genomics in Deal Potentially Worth $51M

NEW YORK - GeneDx said Wednesday that it plans to acquire Fabric Genomics for $33 million in cash with the potential consideration rising to $51 million if certain milestones are met.

CityBiz
Apr 16th, 2025
GeneDx Acquires Fabric Genomics for AI Insights

GeneDx plans to acquire Fabric Genomics, enhancing its leadership in genomic medicine by integrating AI-powered genomic interpretation. This acquisition supports decentralized testing with centralized intelligence, allowing health systems to use GeneDx’s lab or perform sequencing in-house. Fabric Genomics' AI platform aids in interpreting complex genetic cases, facilitating better clinical outcomes globally.

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