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Helix provides genomics-driven solutions for healthcare and life sciences, enabling personalized medicine at scale for health systems, public health entities, and biopharma partners. It operates a large clinical Next-Generation Sequencing lab to generate genetic data and deliver actionable insights for diagnosis, treatment, prevention, and outbreak monitoring. Its products work by sequencing DNA in its lab and translating results into integrated data and workflows that healthcare organizations can use in patient care and research. The goal is to make genomics a practical part of healthcare, helping customers lower costs, accelerate discovery, and improve patient outcomes.
Industries
Biotechnology
Healthcare
Company Size
501-1,000
Company Stage
Series C
Total Funding
$411M
Headquarters
San Mateo, California
Founded
2015
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Total Funding
$411M
Above
Industry Average
Funded Over
6 Rounds
Industry standards
Health Insurance
Parental Leave
401(k) Company Match
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Unlimited Paid Time Off
Remote Work Options
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Helix announces multi-year agreement with Alnylam to drive precision medicine development. Mar 05, 2026, 09:05 ET SAN MATEO, Calif., March 5, 2026 /PRNewswire/ - Helix, the leading enterprise genomics company, today announced a multi-year relationship with Alnylam, the leading RNAi therapeutics company. This agreement provides Alnylam access to Helix's continuously growing, deeply phenotyped GenoSphere(TM) cohorts that cover a wide range of disease areas. Helix GenoSphere(TM) cohorts consist of comprehensive Exome+(R) genomic and rich longitudinal clinical data, enhanced with medical and pharmacy claims. Designed to accelerate Life Sciences research across the development cycle, these de-identified datasets are powered by Helix Research Network(R), the largest and fastest growing precision health network in the world. "We believe that access to the Helix platform will bolster our efforts to identify new targets for RNAi therapeutics, an innovative class of medicines that silence genes that cause or contribute to disease," says Paul Nioi, SVP, Research at Alnylam Pharmaceuticals. "We use human genetics to guide our drug discovery efforts, and we look forward to accessing the Helix platform, which includes data from genetically diverse patients across North America." Key advantages of Helix's datasets and network: * Genomic data from Exome+(R) sequencing provides deep insights into thousands of genes and variants across a wide range of disease areas. * Curated, longitudinal clinical data with an average EHR history of 13 years that includes diagnosis, lab results, and more with regular data refreshes to follow the patient journey. * Fully consented cohort to launch targeted follow-on studies with speed and precision. "We are excited to establish this relationship with Alnylam," said James Lu, M.D., Ph.D., CEO of Helix. "It further validates the unparalleled scale and depth of our platform and exemplifies Helix as a global catalyst in helping transform precision medicine development across major therapeutic areas to improve patient outcomes and lives." To learn more and connect with us about this partnership, Helix GenoSphere and opportunities to collaborate, please visit us here. About Helix: Helix is the leading enterprise genomics platform. The company transforms health systems and enables life science organizations to leverage the power of genomics across their enterprise, creating strategic value and fueling future growth. The Helix Research Network(R)- North America's largest precision health network - accelerates genomic discoveries and translates them into real-world clinical impact. Learn more at www.helix.com. SOURCE Helix
Helix partners with Mawi DNA Technologies to expand access to non-invasive genomic sample collection. Feb 10, 2026 Buccal swab technology complements existing collection approaches, enabling broader participation in population genomics SAN MATEO, Calif. and PLEASANTON, Calif., Feb. 10, 2026 - Helix, the leading enterprise genomics company, has partnered with Mawi DNA Technologies, a leader in DNA sample collection and storage, to expand access to non-invasive DNA collection for genomic sequencing. The collaboration enhances Helix's ability to reach new patient populations while maintaining a flexible, multimodal approach to population genomics. Mawi has developed buccal collection technology, which involves swabbing cells from the inside of a participant's cheek for analysis. The approach is quick, painless, easy to administer, and designed to improve collection efficiency while reducing resampling, failure rates, and overall operational costs. Helix supports multiple DNA collection methods, including blood, saliva, and now buccal swabs, recognizing that no single approach is optimal for every individual or use case. While saliva-based collection is widely used, it may present challenges for some individuals - such as infants, older adults, or people with certain chronic conditions that affect saliva production. Buccal swabs offer an additional option that can help ensure more consistent sample collection. "By adding buccal swab collection to our existing blood and saliva options, we give our partners greater flexibility to design programs that work for their specific populations and settings," said James Lu, M.D., Ph.D., CEO of Helix. "This multimodal approach helps increase participation and generate high-quality genomic data that can drive meaningful clinical and research insights." By incorporating Mawi's buccal collection technology, Helix will further strengthen its sequencing programs by improving collection flexibility and supporting more consistent data generation across diverse cohorts. The partnership enables Helix to meet the needs of health systems and life sciences partners by offering multiple validated pathways for high-quality genomic data. "We are thrilled that Helix has selected Mawi's sample collection technology as an important component of their global effort to understand population genomics on a large scale," said Dr. Bassam El-Fahmawi, CEO and Chief Technical Officer of Mawi DNA. "This initiative aligns with our mission of enabling sample collection accessibility from any individual regardless of age or geographical location. Global sample diversity is critical for a better holistic perspective of understanding genetic diseases and their effects on overall health and wellness across different communities around the world." About Helix: Helix is the leading enterprise genomics platform. The company transforms health systems and enables life science organizations to leverage the power of genomics across their enterprise, creating strategic value and fueling future growth. The Helix Research Network(R)- North America's largest precision health network - accelerates genomic discoveries and translates them into real-world clinical impact. Learn more at www.helix.com. About Mawi DNA Mawi DNA Technologies, founded in 2013, has developed and commercialized the iSWAB technology, an innovative system for collection of biosamples. Mawi's mission is to uphold sample integrity from anywhere in the world at room temperature, enabling true sample diversity across any geography or population segment. The company's flagship product iSWAB-DNA is the only sample collection product on the market proven to produce a high quality DNA sample with low bacterial DNA content. Mawi also supplies products for collection of RNA, microbiome, intact cells, and whole blood. At Mawi, The Future of Biosampling is Here(TM). For more information, visit http://www.mawidna.com. Jan 23, 2026 Mawi DNA buffers stabilize samples without toxic, carcinogenic, or flammable chemicals. Many traditional DNA and RNA stabilization buffers rely on Mar 13, 2025 Mawi was founded with one major goal: to simplify sample collection, transportation, and storage while making the process as painless as possible, especially for babies and the elderly. The collected... Oct 13, 2024
Up to 100,000 canadians could get free genomic testing in new joint study with U.S. hospitals - CTV. Patients at a Toronto hospital will soon have an opportunity to undergo DNA testing for conditions linked to hereditary cancer and heart disease as part of what is being billed as one of Canada's "largest population genomics studies." Princess Margaret Cancer Centre is working with Helix on the initiative. There are currently 15 U.S. hospitals that have already partnered with Helix but Princess Margaret is the first Canadian hospital to join its research network. U.S. genomics company The study, labelled "OurGenes" aims to enroll up to 100,000 participants over the next five years, offering free genetic testing for conditions linked to hereditary cancer and heart disease. "The screening results from this study will allow participants and their healthcare team to make proactive decisions about their health, potentially delaying, reducing, or even preventing cancer or heart disease" officials wrote in Thursday's news release. The goal, researchers say, is to advance early detection and develop approaches to help people manage their health in a "personalized approach." Read more: https://www.ctvnews.ca/toronto/article/up-to-100000-canadians-could-get-free-genomic-testing-in-new-joint-study-with-us-hospitals/
Helix OpCo LLC is thrilled to announce that Helix has been named the "Best Overall Genomics Solution" at the prestigious 2025 MedTech Breakthrough Awards!
Helix is proud to announce the upcoming launch of its new single gene DPYD pharmacogenomic (PGx) test.
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Industries
Biotechnology
Healthcare
Company Size
501-1,000
Company Stage
Series C
Total Funding
$411M
Headquarters
San Mateo, California
Founded
2015
Find jobs on Simplify and start your career today