Hexagon Bio

Hexagon Bio

Genomics-driven discovery of small-molecule inhibitors

Overview

Hexagon Bio uses synthetic biology and data science to discover and develop new medicines by analyzing genomic data from thousands of species to find small molecules that inhibit disease-related proteins. Its proprietary algorithm searches genomes to identify lead compounds and its platform can quickly turn those molecules into candidates suitable for clinical development. The company blends computational biology, chemistry, and synthetic biology to move from genome data to drug candidates faster, and it leverages inexpensive sequencing to access diverse genetic information while producing leads in-house. Its goal is to build a steady pipeline of drug candidates and license them to larger pharmaceutical companies to advance through clinical trials and commercialization.

About Hexagon Bio

Simplify's Rating
Why Hexagon Bio is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

AI & Machine Learning

Biotechnology

Healthcare

Company Size

51-200

Company Stage

Late Stage VC

Total Funding

$183.6M

Headquarters

Menlo Park, California

Founded

2016

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Simplify's Take

What believers are saying

  • $77.3M Series B in 2024 funds preclinical ADC programs expansion.
  • Exponential metagenomic data growth enables discovery of diverse therapeutics first.
  • Licensing model monetizes platform via pharma partnerships across indications.

What critics are saying

  • Corteva JV diverts R&D from oncology to agriculture in 2024.
  • Synaffix and ADC Therapeutics advance superior payloads into clinic by 2025.
  • No Phase 1 candidates by mid-2026 triggers investor withdrawal.

What makes Hexagon Bio unique

  • Proprietary platform mines fungal genomes for novel ADC payloads overcoming resistance.
  • Builds 10x larger proprietary metagenomic database than public ones.
  • Combines data science, synthetic biology, and automation for rapid compound production.

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Funding

Total Funding

$183.6M

Above

Industry Average

Funded Over

4 Rounds

Notable Investors:
Late VC funding comparison data is currently unavailable. We're working to provide this information soon!
Late VC Funding Comparison
Coming Soon

Benefits

Flexible Work Hours

Gym Membership

Growth & Insights and Company News

Headcount

6 month growth

-2%

1 year growth

-6%

2 year growth

-5%
InvestorsObserver
Feb 13th, 2023
Hexagon Bio Raises $77.3 Million Series B Financing and Strengthens Leadership to Expand Novel Computational Discovery Platform and Advance Microbial Genome-Derived Small Molecules

Hexagon Bio Raises $77.3 Million Series B Financing and Strengthens Leadership to Expand Novel Computational Discovery Platform and Advance Microbial Genome-Derived Small Molecules

Vator
Sep 23rd, 2021
The Column Group LLC invests into Hexagon Bio in $61M

Hexagon Bio has raised $61 million in funding led by Nextech, with participation from SoftBank, Casdin Capital and earlier investors The Column Group, 8VC and Two Sigma Ventures.

Business Wire
Sep 22nd, 2021
Hexagon Bio Raises $61 Million to Advance Novel Small-Molecule Medicines Mined from Microbial Genomes

MENLO PARK, Calif.--(BUSINESS WIRE)--Hexagon Bio, a biopharmaceutical company mining microbial genomes to discover new medicines, has raised $61M to advance preclinical programs.

Finsmes
Sep 15th, 2020
Hexagon Bio Closes $47M Series A Financing

Hexagon Bio, Inc., a Menlo Park, Calif.-based biotechnology company turning nature's genomes into medicines, raised $47m in Series A financing

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