Incyte

Incyte

Biopharmaceutical company pursuing drug discovery.

Overview

Incyte develops and sells medicines by discovering and developing new drugs, focusing on diseases in inflammation, autoimmunity, and blood cancers. Its core product, Jakafi (ruxolitinib), is a JAK1/2 inhibitor approved to treat a rare blood cancer and works by blocking JAK enzymes to reduce abnormal blood cell growth. The company also expands its pipeline through research collaborations, partnerships, and acquisitions, such as the 2024 purchase of Escient Pharmaceuticals to strengthen its inflammation and autoimmune portfolio. Unlike some competitors that rely mainly on internal programs, Incyte combines in-house discovery with external collaborations and strategic deals to grow its drug candidates from early research to approved therapies. The goal is to deliver medicines that help patients with serious diseases by building a diverse, clinically validated portfolio of treatments through internal efforts and partnerships.

Significant Headcount Growth

About Incyte

Simplify's Rating
Why Incyte is rated
C+
Rated C on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Biotechnology

Healthcare

Company Size

1,001-5,000

Company Stage

IPO

Headquarters

Chadds Ford Township, Pennsylvania

Founded

1991

Get referred to Incyte

See people who can refer or advise you

Simplify Jobs

Simplify's Take

What believers are saying

  • Q2 2026 revenue hit $1.67 billion, up 38%, beating estimates.
  • Opzelura sales reached $450 million in Q2 2026; CMS settlement lifted 2026 guidance.
  • Vega closed July 6, 2026, adding Phase 3 VWD asset VGA039 and pipeline depth.

What critics are saying

  • Jakafi exclusivity erodes around 2028, threatening Incyte's largest cash engine.
  • CMS Opzelura settlement removed a lawsuit, but preserved rebate-policy exposure across JAK products.
  • Shrinking Wilmington expansion on February 11, 2026 signals execution discipline and incentive clawback risk.

What makes Incyte unique

  • Jakafi and Opzelura anchor diversified cash flows across hematology and dermatology.
  • Opzelura gained EU approval July 29, 2026, expanding steroid-free JAK leadership.
  • Vega acquisition and INCA033989 broaden rare-disease optionality beyond Jakafi.

Help us improve and share your feedback! Did you find this helpful?

Funding

Total Funding

$44.3M

Above

Industry Average

Funded Over

1 Rounds

Post IPO Equity funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Equity Funding Comparison
Coming Soon

Stock Price

Growth & Insights and Company News

Headcount

6 month growth

11%

1 year growth

11%

2 year growth

11%
HealthTech HotSpot
Aug 17th, 2026
Global Vitiligo Foundation applauds Incyte's "Moments of Clarity" Campaign for elevating patient voices and advancing vitiligo awareness.

Global Vitiligo Foundation applauds Incyte's "Moments of Clarity" Campaign for elevating patient voices and advancing vitiligo awareness. MECHANICSBURG, Pa.-(BUSINESS WIRE)-The Global Vitiligo Foundation (GVF) proudly recognizes and supports Incyte's Moments of Clarity campaign, a powerful storytelling initiative that highlights the lived experiences of individuals with nonsegmental vitiligo. Through authentic patient narratives, the campaign closely aligns with GVF's mission to improve the quality of life for people affected by vitiligo through education, advocacy, and community connection. Moments of Clarity captures pivotal turning points in patients' journeys - from recognizing the need for support, to seeking care, to experiencing meaningful progress in managing their condition. These stories not only raise awareness of vitiligo but also foster understanding, empowerment, and hope within the global vitiligo community. "This campaign reflects the heart of what GVF stands for: ensuring that people living with vitiligo feel seen, supported, and empowered," said Seemal R. Desai, MD, President of the Global Vitiligo Foundation. "By elevating real voices and real journeys, Moments of Clarity helps break down stigma while reinforcing the importance of informed care and community connection." This year, Incyte introduces three new stories from patients who exemplify the resilience and self-discovery of the nonsegmental vitiligo treatment process as they experience meaningful improvement in their condition with Opzelura(R)(ruxolitinib) cream 1.5%: * Carolyn, who gave Opzelura a second try and learned that persistence and patience are key to seeing results with treatment. By staying consistent and connecting with the vitiligo community, she is now achieving her personal treatment goals. * Tiffanie, diagnosed at age 7, who embraced a journey of self-love over decades before choosing to explore treatment. Inspired by her grandmother's courage, she now channels her experience into advocacy through the I AM GREAT MOVEMENT. * Kasey, a mother and sports enthusiast, who spent years concealing her vitiligo before reclaiming her confidence. Now working at Incyte as a sales representative, she uses her personal experience to help others find hope and a sense of control. "These stories reflect the diversity of the vitiligo experience and highlight the importance of individualized journeys," Dr. Desai added. "They reinforce that treatment decisions are deeply personal and that support systems, whether clinical or community-based, play a vital role in overall well-being." GVF's vision is a world where the burden of vitiligo is eliminated through compassion, care, and cure. Initiatives like Moments of Clarity contribute meaningfully to that vision by increasing public awareness, encouraging patient engagement, and promoting conversations around care options and emotional well-being. GVF is proud to have Incyte as a sponsor in support of the global vitiligo community. The Global Vitiligo Foundation encourages patients, caregivers, and healthcare providers to explore these inspiring stories and learn more about the journeys of individuals living with nonsegmental vitiligo by visiting www.mymomentsofclarity.com. Together, through education, storytelling, and collaboration, GVF and partners like Incyte continue to advance a more informed, compassionate, and hopeful future for the vitiligo community. About the Global Vitiligo Foundation The Global Vitiligo Foundation (GVF) is a nonprofit organization dedicated to improving the lives of people with vitiligo through research, education, advocacy, and support. GVF works to increase public understanding, promote collaboration among experts, and empower individuals affected by vitiligo to thrive.

MarketBeat
Aug 4th, 2026
Incyte (NASDAQ:INCY) EVP sells $5,005,254.54 in stock.

Incyte (NASDAQ:INCY) EVP sells $5,005,254.54 in stock. August 4, 2026 Key points. * Incyte EVP Patrick Mayes sold 41,899 shares for approximately $5.01 million at an average price of $119.46 under a pre-arranged Rule 10b5-1 trading plan, reducing his direct holdings by 40.54% to 61,441 shares. * Incyte shares rose 1.9% to $120.65, while the company's latest quarterly results exceeded expectations: earnings were $3.09 per share versus a $2.15 estimate, and revenue increased 37.7% year over year to $1.67 billion. * Analyst sentiment is mixed, with a consensus "Hold" rating and a $120.40 price target; targets range from $109 to $155, while institutional investors own 96.97% of the company. * Five stocks to consider instead of Incyte. Incyte Corporation (NASDAQ:INCY - Get Free Report) EVP Patrick Mayes sold 41,899 shares of the company's stock in a transaction that occurred on Friday, July 31st. The stock was sold at an average price of $119.46, for a total transaction of $5,005,254.54. Following the completion of the sale, the executive vice president directly owned 61,441 shares of the company's stock, valued at $7,339,741.86. The trade was a 40.54% decrease in their position. The sale was disclosed in a document filed with the SEC, which is available at this hyperlink. The transaction was executed under a pre-arranged Rule 10b5-1 trading plan. Incyte stock up 1.9%. INCY stock traded up $2.22 during trading on Tuesday, hitting $120.65. 2,052,860 shares of the company's stock traded hands, compared to its average volume of 1,796,887. The firm has a market capitalization of $24.46 billion, a P/E ratio of 15.37, a PEG ratio of 3.96 and a beta of 0.76. Incyte Corporation has a 1 year low of $76.45 and a 1 year high of $132.60. The business has a fifty day simple moving average of $109.97 and a two-hundred day simple moving average of $102.32. Incyte (NASDAQ:INCY - Get Free Report) last posted its earnings results on Tuesday, July 28th. The biopharmaceutical company reported $3.09 earnings per share for the quarter, topping analysts' consensus estimates of $2.15 by $0.94. The company had revenue of $1.67 billion during the quarter, compared to analyst estimates of $1.50 billion. Incyte had a return on equity of 29.93% and a net margin of 27.71%.Incyte's revenue was up 37.7% on a year-over-year basis. During the same quarter in the prior year, the business earned $1.57 earnings per share. On average, equities research analysts predict that Incyte Corporation will post 2.5 EPS for the current fiscal year. Institutional trading of Incyte. Institutional investors have recently made changes to their positions in the business. Jacobi Capital Management LLC grew its stake in Incyte by 0.9% during the fourth quarter. Jacobi Capital Management LLC now owns 10,613 shares of the biopharmaceutical company's stock worth $1,048,000 after buying an additional 99 shares during the period. Oregon Public Employees Retirement Fund raised its stake in shares of Incyte by 0.5% in the 4th quarter. Oregon Public Employees Retirement Fund now owns 18,870 shares of the biopharmaceutical company's stock valued at $1,864,000 after acquiring an additional 100 shares during the period. Smartleaf Asset Management LLC lifted its holdings in shares of Incyte by 7.5% during the 4th quarter. Smartleaf Asset Management LLC now owns 1,628 shares of the biopharmaceutical company's stock valued at $161,000 after acquiring an additional 113 shares in the last quarter. Bank of Nova Scotia lifted its holdings in shares of Incyte by 0.7% during the 2nd quarter. Bank of Nova Scotia now owns 17,041 shares of the biopharmaceutical company's stock valued at $1,160,000 after acquiring an additional 124 shares in the last quarter. Finally, Perbak Capital Partners LLP boosted its position in Incyte by 2.5% during the 3rd quarter. Perbak Capital Partners LLP now owns 5,298 shares of the biopharmaceutical company's stock worth $449,000 after purchasing an additional 129 shares during the period. Institutional investors and hedge funds own 96.97% of the company's stock. Analyst upgrades and downgrades. INCY has been the subject of a number of analyst reports. Stifel Nicolaus set a $145.00 price objective on Incyte in a research note on Tuesday, July 28th. Leerink Partners lifted their target price on Incyte from $131.00 to $155.00 and gave the company an "outperform" rating in a research note on Monday. Royal Bank Of Canada boosted their target price on shares of Incyte from $99.00 to $109.00 and gave the stock a "sector perform" rating in a report on Wednesday, July 29th. BMO Capital Markets raised their price target on shares of Incyte from $112.00 to $130.00 and gave the company a "market perform" rating in a report on Wednesday, July 29th. Finally, Oppenheimer reaffirmed a "market perform" rating and issued a $120.00 price objective on shares of Incyte in a research report on Tuesday, July 28th. Ten equities research analysts have rated the stock with a Buy rating and thirteen have issued a Hold rating to the company. Based on data from MarketBeat.com, Incyte currently has a consensus rating of "Hold" and a consensus price target of $120.40. Discover more Market Cap Calculator Business News AI Stocks Report About Incyte. Incyte Corporation is a Wilmington, Delaware-based biopharmaceutical company focused on the discovery, development and commercialization of novel therapies in oncology and inflammation. Since its founding in 2002, Incyte has grown from a small research organization into a global enterprise, advancing a portfolio of internally developed and partnered assets. The company's research and development efforts center on small-molecule drugs and biologics that modulate critical signaling pathways implicated in cancer, autoimmune disorders and rare diseases. The company's flagship product is Jakafi(R)(ruxolitinib), a Janus kinase (JAK) inhibitor approved for the treatment of myelofibrosis and polycythemia vera. This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest reporting and unbiased coverage. Please send any questions or comments about this story to [email protected]. Before you consider Incyte, you'll want to hear this. MarketBeat keeps track of Wall Street's top-rated and best performing research analysts and the stocks they recommend to their clients on a daily basis. MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on... and Incyte wasn't on the list. While Incyte currently has a Hold rating among analysts, top-rated analysts believe these five stocks are better buys. Discover the next wave of investment opportunities with our report, 7 Stocks That Will Be Magnificent in 2026. Explore companies poised to replicate the growth, innovation, and value creation of the tech giants dominating today's markets.

Delaware Business Now
Jul 30th, 2026
Delaware to use $$ returned by Incyte for small businesses.

Delaware to use $$ returned by Incyte for small businesses. * By Ella Walker - Spotlight Delaware * Jul 30, 2026 Updated 2 hrs ago * 0 Months after local pharmaceutical giant Incyte abandoned plans to move its headquarters to Wilmington, state officials reallocated millions of grant dollars from the project to a new initiative to support small businesses. The change in direction - from supporting one of the largest commercial projects in recent years to starting an expanded grant program for small businesses - is in line with Gov. Matt Meyer's approach to economic development. State leaders recently struck a deal to shrink Incyte's taxpayer-funded relocation grant to $2.8 million, down from $14.7 million. Those funds will function as a job creation grant for the more than 200 employees moving into the building. Delaware's Small Business Director CJ Bell called the negotiations to amend the deal "smooth." As part of its restructuring of Incyte's grant, the state reallocated $4.5 million to an economic development initiative to revive business districts around the state. The rest of the money will return to the state's Strategic Fund, which supports business expansion in Delaware. "This was an opportune time to take advantage of Incyte and their good collaboration with us," Bell said. What happened to the Incyte project? For more than a decade, Incyte has maintained its corporate headquarters just outside Wilmington's city limits in the Alapocas community. Buoyed largely by sales of successful cancer drugs, the company in recent years had attempted to grow the existing campus, but faced resistance from neighbors. In light of the opposition, state and city officials began to collaborate then on a pitch to persuade the company's leaders to instead expand downtown. The efforts proved successful when Incyte announced in the spring of 2024 that it had purchased the pair of Bracebridge office buildings - which once served as the global headquarters for MBNA. The nearly $50 million purchase was seen as a significant win for the city because the largely empty buildings had long weighed on the city's office market. Following the purchase, Delaware state officials awarded Incyte with nearly $15 million to help it pay for the move into Wilmington. During a meeting of the state committee that approves such subsidies, Kurt Foreman, then the head of Delaware's public-private economic development arm, the Delaware Prosperity Partnership, said the deal could lead to the creation of 866 new jobs in Wilmington's downtown core. Months after the state's grant approval, Wilmington officials quietly awarded Incyte another $10 million for the expansion. During the remainder of 2024 and through 2025, Incyte spent nearly $29 million on a renovation of its new properties, according to a company earnings report. Then, at the start of last winter, the work appeared to cease. The stoppage came just months after Incyte had selected Bill Meury, a pharmaceutical executive with ties to Boston-area startups, as its new CEO, replacing longtime leader Hervé Hoppenot, who signed off on the deal with Delaware leaders. Weeks after assuming the helm, Meury stated the company would take "a fresh look" at its business, including its capital allocation, according to a report from Reuters. By February, Incyte publicly announced its scaled-back expansion plans through a series of media interviews in which officials said the company would sell the Bracebridge buildings to BPG, then lease back some of the space. No new dollars will be flowing to BPG as part of their now-reduced investment into the Bracebridge complex, Bell told Spotlight Delaware. City officials also clawed back some grant money from the company. As part of an amended agreement with the city, Incyte returned $5 million, but it may retain the other $5 million if the company employs an annual average of 200 full-time employees at Bracebridge for a decade, a city spokesperson said. New grant program. Meanwhile, the state is using $4.5 million in reallocated grant money to create the Delaware Commercial Corridor Initiative, a program to support brick-and-mortar businesses - or what Bell calls the "missing middle." The program will operate as an expansion of the long-running Downtown Development Districts program, which grants taxpayer-backed funds to businesses in a handful of historic central business districts across the state to improve and sustain the commercial areas. To be eligible, a recipient must be located adjacent to an established Downtown Development District or in a commercially developed corridor that is zoned for commercial or business use and located in a Level 1 or Level 2 Investment Area under the State's 2025 Strategies for State Policies and Spending. That way applicants cannot double-dip into existing grant programs, officials said. Businesses may apply for funding for interior renovations, exterior and facade improvements, equipment purchases and code compliance upgrades, b building purchases and rent expenses are not eligible. The new program will outsource the decision-making to a bank or financial institution in each county. Grants will cover 10% to 25% of a project's cost, up to $25,000 per business, with the remaining project financing provided through private lending institutions. Bell expects the first round of funds to go out to lenders by the end of September, after what he hopes will be a competitive bidding process. * indicates required Email Format

Associated Press
Jul 29th, 2026
Opzelura becomes first steroid-free topical JAK inhibitor approved in EU for moderate atopic dermatitis

The European Commission has approved Opzelura (ruxolitinib) cream for treating moderate atopic dermatitis in adults, making it the first steroid-free topical JAK inhibitor approved in the EU for this condition. The treatment is for patients who have not responded adequately to topical corticosteroids and topical calcineurin inhibitors. The approval, announced by Incyte, follows a positive opinion from the European Medicines Agency's Committee for Medicinal Products for Human Use in June 2026. This marks Opzelura's second indication in Europe, having previously been approved for non-segmental vitiligo. The decision is based on the Phase 3b TRuE-AD4 study, which showed Opzelura significantly improved clinical signs and symptoms of moderate atopic dermatitis, including itch relief as early as day two. At week eight, 84.3% of patients achieved a 75% improvement in disease severity.

Yahoo Finance
Jul 28th, 2026
Incyte beats Q2 forecasts with $1.67B revenue but shares fall on weaker full-year guidance

Incyte reported second-quarter earnings per share of $3.09, beating expectations by $1.10, whilst revenue of $1.67 billion surpassed the consensus estimate of $1.42 billion. Total revenue increased 38% year-on-year, driven by strong performance across its commercial portfolio. The results included a one-time $246 million benefit from a CMS agreement relating to Opzelura. Excluding this, total net sales grew 17%. Jakafi generated sales of $817 million, up 7%, whilst Opzelura recorded sales of $450 million, rising 173% (or 24% excluding the CMS benefit). Despite the quarterly beat, shares slipped in pre-market trading after the company raised its full-year sales guidance to $5.13-$5.26 billion, below the analyst consensus of $5.72 billion.

Recently Posted Jobs

Sign up to get curated job recommendations

There are no jobs for Incyte right now.

Find jobs on Simplify and start your career today

We update Incyte's jobs every few hours, so check again soon! Browse all jobs →