Insmed

Insmed

Develops therapies for rare diseases

Overview

Insmed focuses on developing and delivering therapies for serious and rare diseases. Its products come from a pipeline of clinical trials and approved treatments, sold to patients in global markets with offices in Bridgewater, NJ, Europe, and Japan. The company’s work combines research and development, regulatory approvals, and commercialization to bring therapies from discovery to patients. Insmed differentiates itself by addressing unmet medical needs in rare diseases and maintaining a global infrastructure that supports development, approval, and patient access. The goal is to improve patient outcomes by providing effective treatments for conditions with limited existing options.

Significant Headcount Growth

About Insmed

Simplify's Rating
Why Insmed is rated
B
Rated B on Competitive Edge
Rated A on Growth Potential
Rated C on Differentiation

Industries

Biotechnology

Healthcare

Company Size

1,001-5,000

Company Stage

IPO

Headquarters

Richmond, Virginia

Founded

1988

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Simplify's Take

What believers are saying

  • August 6, 2026 Q2 revenue hit $425.5 million, up 296% year over year.
  • BRINSUPRI revenue reached $309.2 million, and management lifted 2026 guidance to $1.4 billion.
  • Insmed ended June 2026 with $1.2 billion cash and expects cash-flow positivity in 2027.

What critics are saying

  • TPIP contributes zero revenue today, yet over $6 billion of peak value depends on it.
  • Europe launch of Brinsupri remains delayed after management cited U.S. MFN pricing uncertainty.
  • Pomerantz opened a January 2026 securities investigation after brensocatib's CRSsNP failure.

What makes Insmed unique

  • Brinsupri became first-to-market DPP-1 inhibitor for bronchiectasis after August 2025 approval.
  • Arikayce owns entrenched Mycobacterium avium complex revenue and supports a broader respiratory franchise.
  • TPIP spans PAH, PH-ILD, IPF, and PPF, creating unusually large optionality.

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Funding

Total Funding

$3.4B

Above

Industry Average

Funded Over

10 Rounds

Post IPO Equity funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Equity Funding Comparison
Coming Soon

Benefits

Flexible Work Hours

Health Insurance

Paid Vacation

Employee Stock Purchase Plan

Company Equity

Stock Price

Growth & Insights and Company News

Headcount

6 month growth

22%

1 year growth

22%

2 year growth

22%
Yahoo Finance
Aug 7th, 2026
Insmed raises peak sales estimate to $14B, but $6B hinges on unapproved drug

Insmed's stock trades at 25.3 times sales despite falling 37% from its 52-week high, as revenue nearly tripled to $1.1 billion over the past twelve months. The premium reflects management's raised peak-sales estimate of over $14 billion across three lead programmes. BRINSUPRI, the company's bronchiectasis drug, generated $309.2 million in its third full quarter, up 49% sequentially. Management raised full-year BRINSUPRI guidance to between $1.25 billion and $1.4 billion. However, more than $6 billion of the peak estimate depends on TPIP, an inhaled treatment for pulmonary arterial hypertension, which is still in Phase III trials. The company ended June with $1.2 billion in cash, which management says will fund operations to cash flow positivity in 2027.

Yahoo Finance
Aug 7th, 2026
Insmed shares soar 33.86% as Brinsupri drives fourfold revenue growth to $425.5M

Insmed's share price surged 33.86% on Thursday to close at $132.55 after the biopharmaceutical company nearly quadrupled its revenues in the second quarter. Total revenues soared 296% to $425.5 million from $107.4 million year-on-year, driven primarily by Brinsupri, its non-cystic fibrosis bronchiectasis treatment, which contributed $309.2 million. The company's lung disease treatment Arikayce added $116.3 million in revenues, up 8% year-on-year. The strong performance helped slash net loss by 96% to $13.2 million from $321.7 million in the same period last year. Insmed raised its full-year revenue guidance to between $1.25 billion and $1.4 billion, representing growth of 624% to 710.6% year-on-year. Investors will be watching whether Brinsupri can sustain momentum whilst the company awaits regulatory decisions for brensocatib in Japan in the second half of 2026.

Yahoo Finance
Aug 6th, 2026
Insmed raises BRINSUPRI revenue guidance to $1.4B as Q2 sales surge 49% sequentially

Insmed reported Q2 2026 revenue of $309.2 million for BRINSUPRI, up 49% sequentially, whilst ARIKAYCE generated $116.3 million, rising 8% year-over-year. The company raised its full-year 2026 BRINSUPRI revenue guidance to $1.25 billion to $1.4 billion and increased peak sales estimates to over $7 billion. BRINSUPRI added approximately 7,000 new patients in Q2, with 90% payer approval and high patient compliance rates. The company maintains a cash position of $1.2 billion and expects to reach cash flow positivity in 2027. Cost of product revenues fell to 16% of revenues, down from 26% in Q2 2025. However, combined R&D and SG&A expenses increased 38% year-over-year. The company expects to incur $50 million in milestone payments to AstraZeneca in the second half of 2026.

Yahoo Finance
Aug 6th, 2026
Insmed reports Q2 revenue of $425M, up 296% year-over-year, beating estimates by 9%

Insmed reported revenue of $425.49 million for Q2 2026, a 296.1% year-over-year increase that beat the consensus estimate of $389.72 million by 9.18%. The company posted a loss of $0.52 per share, narrower than the $1.70 loss a year earlier and beating analyst expectations of $0.69 per share by 24.64%. US revenues reached $378.74 million, significantly exceeding the $334.1 million analyst estimate and marking a 451.4% year-over-year increase. BRINSUPRI generated $309.17 million in total revenue, surpassing the $275.82 million estimate. ARIKAYCE total revenues came in at $116.32 million, slightly above the $113.9 million consensus. Despite the strong results, shares have declined 15% over the past month.

PR Newswire
Aug 6th, 2026
Insmed raises 2026 BRINSUPRI revenue guidance to $1.25B-$1.4B, boosts peak revenue estimate to over $14B

Insmed reported second-quarter 2026 revenues of $425.5 million, driven by strong performance from its respiratory therapies. BRINSUPRI generated $309.2 million, representing 49% growth over the first quarter, whilst ARIKAYCE brought in $116.3 million, up 8% year-over-year. The company raised its 2026 BRINSUPRI revenue guidance to $1.25 billion to $1.40 billion from the previous target of at least $1 billion. ARIKAYCE guidance remained unchanged at $450 million to $470 million. Insmed also increased its peak revenue estimate for its three lead programmes to more than $14 billion combined. This comprises over $7 billion for BRINSUPRI, more than $6 billion for TPIP, and over $1 billion for ARIKAYCE. The company reported a net loss of $13.2 million for the quarter, compared to a loss of $321.7 million in the same period last year.

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