Kura Oncology

Kura Oncology

Clinical-stage oncology company develops targeted therapies

Overview

Kura Oncology develops precision medicines for cancer, focusing on small-molecule drugs that target tumors with specific genetic mutations. It is in the clinical-stage, researching and developing its own drug candidates to eventually bring them to market. Its leading candidate, ziftomenib, blocks the menin-KMT2A/MLL protein interaction, offering a targeted approach for genetically defined acute myeloid leukemia (AML). The company is also pursuing tipifarnib for head and neck squamous cell carcinoma (HNSCC) and other solid tumors. By collaborating with academic institutions and other biotech companies, Kura Oncology expands its pipeline and advances therapies through clinical trials. The goal is to deliver effective, targeted cancer treatments for patients with unmet medical needs and to grow its portfolio through research, development, and partnerships.

Funded Recently

About Kura Oncology

Simplify's Rating
Why Kura Oncology is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Biotechnology

Healthcare

Company Size

201-500

Company Stage

IPO

Headquarters

San Diego, California

Founded

2014

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Simplify's Take

What believers are saying

  • Q2 2026 KOMZIFTI revenue reached $9.1 million, up 57% sequentially.
  • June 11, 2026 KOMET-007 data showed 96% CRc in newly diagnosed NPM1-mut AML.
  • August 10, 2026 Blood publication highlighted ziftomenib resistance-evading binding and activity.

What critics are saying

  • Kura reported $68.3 million Q2 2026 net loss despite launch momentum.
  • KOMET-017 topline results arrive in 2028, leaving years for rivals to seize share.
  • If Komzifti stalls, Kura loses its only commercial engine before 2028.

What makes Kura Oncology unique

  • Kura's Komzifti became the first approved menin inhibitor for NPM1-mutated AML in 2025.
  • Kyowa Kirin paid $330 million upfront and funds ex-U.S. commercialization.
  • Darlifarnib extends Kura beyond AML into KRAS-mutant solid tumors and RCC.

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Funding

Total Funding

$1.2B

Above

Industry Average

Funded Over

11 Rounds

Post IPO Equity funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Equity Funding Comparison
Coming Soon

Benefits

Health Insurance

Dental Insurance

Vision Insurance

401(k) Retirement Plan

401(k) Company Match

Paid Vacation

Paid Holidays

Paid Paternity/Maternity Leave

Home Office Stipend

Lifestyle Spending Stipend

Commuter Stipend

Wellness Program

Gym Membership

Company Social Events

Stock Price

Growth & Insights and Company News

Headcount

6 month growth

↑ 1%

1 year growth

↑ 2%

2 year growth

↑ 4%
Yahoo
Sep 29th, 2026
Caspian Therapeutics and Kura Oncology report preclinical data for diabetes candidate KO-7246.

Caspian Therapeutics and Kura Oncology report preclinical data for diabetes candidate KO-7246. Fiona Craig Updated Tue, September 29, 2026 at 5:27 AM PDT * KO-7246, an oral menin inhibitor developed for diabetes, showed promising results in preclinical studies, normalizing blood glucose levels and increasing insulin production in animal models. Caspian Therapeutics and Kura Oncology (NASDAQ:KURA) reported preclinical data for KO-7246, an oral menin inhibitor being developed for diabetes, at the 62nd European Association for the Study of Diabetes Annual Meeting in Milan, Italy, on September 29, 2026. The data were generated by Kura Oncology before Caspian's launch in September 2026 and were presented by Kura Chief Scientific Officer Francis Burrows. KO-7246 is an orally bioavailable compound currently undergoing IND-enabling development. The findings reported to date are preclinical and have not established safety or efficacy in humans. KO-7246 evaluated in Type 1 diabetes rat model. In a rat model of Type 1 diabetes, KO-7246 normalised fasting blood glucose in a majority of treated animals and increased stimulated C-peptide, a marker of endogenous insulin production, according to the presented data. Pancreatic islets in animals that responded to treatment regenerated to between 40% and 90% of the levels observed in healthy controls by Day 56. The normalised glucose levels and increased C-peptide were maintained for at least one month after treatment was discontinued, according to the companies. β-Cell mass increases in Type 2 diabetes model. In a mouse model of Type 2 diabetes, KO-7246 reduced fasting blood glucose and increased insulin and C-peptide levels. The compound was also associated with a 3.4-fold increase in β-cell mass. The companies reported enhanced activity when KO-7246 was combined with semaglutide. The observed increase in insulin was not associated with hypoglycaemia in the model. In human pancreatic islet models, KO-7246 increased β-cell proliferation and improved insulin release in response to glucose without stimulating the growth of other islet cells, according to the presented findings. Presentation includes comparison with BMF-219. The presentation also included preclinical comparisons with BMF-219, or icovamenib, another compound in clinical development for diabetes. According to the data presented by Caspian and Kura, BMF-219 showed no discernible activity against menin in a biochemical assay and did not normalise glycaemic control or increase β-cell mass in the Type 1 diabetes model. The supplied material does not include a response from BMF-219's developer regarding the comparison. KO-7246 advances through ind-enabling development. "Caspian was formed to translate this biology into potentially disease-modifying medicines," said Robert Spencer, President and Chief Operating Officer of Caspian Therapeutics. "We are advancing KO-7246 through IND-enabling development toward initial clinical evaluation." The programme remains at the preclinical stage, and the supplied information does not provide a timetable for the start of human clinical trials. Caspian and Kura management are scheduled to host a webcast and conference call on October 13, 2026, at 4:30 p.m. ET. Kura Oncology stock price

Fierce Biotech
Sep 9th, 2026
Kura creates Lilly-backed spinout armed with $50M to advance next-gen diabetes therapy

Kura Oncology has spun out a biotech armed with $50 million in fresh funding to take forward a next-generation diabetes treatment. | Kura Oncology has spun out a biotech armed with $50 million in fresh funding to take forward a next-generation diabetes treatment.

Business Insider
Sep 9th, 2026
Kura Oncology spins out Caspian Therapeutics with $50M to develop menin inhibitor for diabetes

Kura Oncology has launched Caspian Therapeutics with $50 million in financing to develop menin inhibitors for diabetes treatment. The financing was led by BVF Partners, with participation from T1D Fund, Invus, Montanova, Eli Lilly and Company, and Kura Oncology itself. Caspian will advance KO-7246, a next-generation menin inhibitor designed for chronic metabolic diseases. Preclinical studies show the compound can selectively expand pancreatic β cells, increase insulin production, and improve blood sugar control in Type 1 and Type 2 diabetes models. Kura Oncology retains approximately 50% ownership of Caspian on a fully diluted basis whilst maintaining its focus on oncology. The financing will fund KO-7246 through IND-enabling development and initial clinical proof-of-concept trials in diabetes patients. Robert Spencer has been appointed President and Chief Operating Officer of Caspian.

Yahoo Finance
Sep 8th, 2026
Kura Oncology appoints Jennifer Fulk as CFO to lead commercial-stage transition

Kura Oncology, a biopharmaceutical company focused on precision cancer medicines, has appointed Jennifer Fulk as chief financial officer, effective 8 September 2026. Fulk brings over 20 years of financial and operating leadership experience in biopharmaceuticals and public companies. She previously spent more than 15 years at Eli Lilly and Company in senior finance roles, including chief financial officer of Lilly's US Bio-Medicines business with profit and loss responsibility for a $2.5 billion neuroscience and immunology business. She also served as chief financial officer at publicly traded Talkspace and Soleno Therapeutics. Fulk will report to Troy Wilson, president, chief executive officer and chairman of the board, as Kura enters its next phase as a commercial-stage company.

GlobeNewswire
Sep 8th, 2026
Kura Oncology appoints Jennifer Fulk as Chief Financial Officer.

Kura Oncology appoints Jennifer Fulk as Chief Financial Officer. - Seasoned public company CFO with deep biopharmaceutical finance experience across commercial operations, R&D portfolio management, investor relations, and capital allocation - SAN DIEGO, Sept. 08, 2026 (GLOBE NEWSWIRE) - Kura Oncology, Inc. (Nasdaq: KURA, "Kura"), a biopharmaceutical company focused on precision medicines for the treatment of cancer, today announced the appointment of Jennifer Fulk as Chief Financial Officer, effective September 8, 2026. Ms. Fulk will join Kura's senior leadership team and report to Troy Wilson, Ph.D., J.D., President, Chief Executive Officer and Chairman of the Board. "We are delighted to welcome Jennifer to Kura as we enter our next phase of development as a commercial-stage company," said Dr. Wilson. "Jennifer brings both an exceptional breadth of experience across commercial, finance, R&D portfolio management, investor relations, and global operations, and a strong track record as a public-company CFO. As we work to maximize the commercial potential of KOMZIFTI(R), broaden the opportunity for ziftomenib and advance darlifarnib, her strategic judgment and financial leadership will be invaluable to disciplined capital allocation, strong execution, and long-term value creation." Ms. Fulk brings more than 20 years of financial and operating leadership experience spanning biopharmaceuticals, public companies, and high-growth businesses. After more than 15 years at Eli Lilly and Company, she served in a series of senior finance and operating leadership roles, including as Chief Financial Officer of publicly traded Talkspace, Chief Operating Officer and Chief Financial Officer of 120Water, and, most recently, Chief Financial Officer of Soleno Therapeutics. During her tenure at Lilly, Ms. Fulk held increasingly senior roles spanning commercial finance, research and development, investor relations, treasury, and global operations. Her positions included Chief Financial Officer of Lilly's U.S. Bio-Medicines business, with P&L responsibility for a $2.5 billion U.S. neuroscience and immunology business; Vice President, Investor Relations; and Executive Director, Lilly Global Oncology Finance, where she provided financial leadership for an annual R&D portfolio of approximately $1 billion. "Kura has established a strong commercial foundation with KOMZIFTI and is advancing two differentiated precision-oncology franchises with significant potential," said Ms. Fulk. "I am excited to join Troy and the Kura team at this important stage of the company's evolution. I look forward to helping Kura build on its commercial momentum, allocate capital to its highest-value opportunities and execute with discipline across the business." Ms. Fulk holds a Bachelor of Science in Information Systems and a Master of Business Administration from Indiana University. About Kura Oncology Kura Oncology is a biopharmaceutical company committed to realizing the promise of precision medicines for the treatment of cancer. Kura's pipeline of small molecule drug candidates is designed to target cancer signaling pathways and address high-need hematologic malignancies and solid tumors. Kura developed and is commercializing KOMZIFTI(R)(ziftomenib), the FDA-approved once-daily, oral menin inhibitor for the treatment of adults with relapsed or refractory NPM1-mutated acute myeloid leukemia and continues to pioneer advancements in menin inhibition and farnesyl transferase inhibition. For additional information, please visit the Kura website and follow us on X and LinkedIn. Forward-Looking Statements This news release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include statements regarding, among other things, the expected contributions of Ms. Fulk as Chief Financial Officer; Kura's plans to maximize the commercial potential of KOMZIFTI, broaden the opportunity for ziftomenib and advance darlifarnib; the potential of Kura's two differentiated precision-oncology franchises; Kura's capital allocation strategy and plans for disciplined execution across the business; and Kura's ability to generate long-term value. Factors that may cause actual results to differ materially include the risk that the expected contributions of Ms. Fulk may not be as expected; the risk that Kura's actual future financial and operating results may differ from its expectations or goals; and other risks associated with the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. You are urged to consider statements that include the words "may," "will," "would," "could," "should," "believes," "estimates," "projects," "potential," "expects," "plans," "anticipates," "intends," "continues," "designed," "goal," or the negative of those words or other comparable words to be uncertain and forward-looking. For a further list and description of the risks and uncertainties the Company faces, please refer to the Company's periodic and other filings with the Securities and Exchange Commission, which are available at www.sec.gov. Such forward-looking statements are current only as of the date they are made, and Kura assumes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise. Kura Oncology contact

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