Kyverna Therapeutics

Kyverna Therapeutics

T cell therapies for autoimmune diseases

Overview

Kyverna Therapeutics develops cell therapies for autoimmune diseases. The company uses synthetic biology, immunology, and cell engineering to create engineered T cells designed to target and modulate the root causes of autoimmunity. Its therapies are intended to be given by a single infusion to achieve long-lasting disease control, reducing or eliminating the need for ongoing treatments. Kyverna pursues in-licensing and collaboration opportunities to broaden its technology and capabilities and to advance its therapies toward patients through development and sales to patients and healthcare providers. The core goal is to provide durable, well-tolerated treatments that can offer substantial, long-term relief for people with autoimmune diseases.

About Kyverna Therapeutics

Simplify's Rating
Why Kyverna Therapeutics is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Biotechnology

Healthcare

Company Size

51-200

Company Stage

IPO

Headquarters

Emeryville, California

Founded

2018

People at Kyverna Therapeutics

People at Kyverna Therapeutics who can refer or advise you

Simplify Jobs

Simplify's Take

What believers are saying

  • miv-cel could become first FDA-approved CAR T therapy for autoimmune disease in 2026.
  • Updated Phase 2 data showed 81% symptom improvement in stiff-person syndrome patients.
  • Generalized myasthenia gravis data showed 100% patients achieved rapid, sustained clinical benefit.

What critics are saying

  • SPS Phase 2 topline data in early 2026 may fail efficacy or safety thresholds.
  • Organizers may delay BLA due to insufficient long-term safety data from 52-week follow-up.
  • COMPARE trial may lose to rituximab, invalidating immune reset narrative and blocking RA expansion.

What makes Kyverna Therapeutics unique

  • Kyverna is the first company advancing CAR T-cell therapy for autoimmune disease.
  • Its miv-cel targets B cells to reset the immune system after single infusion.
  • Unlike chronic treatments, one infusion aims for durable, drug-free remission in patients.

Help us improve and share your feedback! Did you find this helpful?

Funding

Total Funding

$489M

Above

Industry Average

Funded Over

4 Rounds

Notable Investors:
IPO funding comparison data is currently unavailable. We're working to provide this information soon!
IPO Funding Comparison
Coming Soon

Benefits

Hybrid Work Options

Remote Work Options

Performance Bonus

Stock Price

Growth & Insights

Headcount

6 month growth

1%

1 year growth

-1%

2 year growth

4%

Recently Posted Jobs

Sign up to get curated job recommendations

Kyverna Therapeutics is Hiring for 13 Jobs on Simplify!

Find jobs on Simplify and start your career today

Don't see your dream role? Check out thousands of other roles on Simplify. Browse all jobs →