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Life Edit Therapeutics develops gene-editing tools and therapies using RNA-guided nucleases and base editors built from non-pathogenic organisms. It combines in-house programs with collaborations, such as with Moderna, to co-develop medicines and generate milestones and royalties. The editing system uses programmable enzymes guided by RNA to target DNA sequences and introduce precise edits in cells, enabling potential treatments for genetic diseases. The company aims to expand access to its gene-editing toolkit and create curative cell and gene therapies by growing a large, diverse platform and pursuing diverse partnerships.
Industries
Biotechnology
Healthcare
Company Size
51-200
Company Stage
N/A
Total Funding
N/A
Headquarters
Durham, North Carolina
Founded
2017
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Health Insurance
Dental Insurance
Vision Insurance
Mental Health Support
Wellness Program
401(k) Retirement Plan
401(k) Company Match
Life Insurance
Disability Insurance
Health Savings Account/Flexible Spending Account
Commuter Benefits
Phone/Internet Stipend
Unlimited Paid Time Off
Paid Holidays
Parental Leave
Professional Development Budget
Moderna has also branched out into other trendy modalities with its hard-earned COVID cash, including a February deal with Life Edit Therapeutics to work on gene therapies.
In connection with Novo Nordisk’s participation in the series D financing, ElevateBio’s subsidiary Life Edit Therapeutics has partnered with the Big Pharma to develop base editing therapies.
DURHAM – Gene editing from a Durham-based firm that will target possible new therapeutics has led to a deal with international drug firm Novo Nordisk worth a potential $2 billion if not more.Life Edit, which is owned by Boston based ElevateBio, and Novo Nordisk, which has a big presence in the Triangle, announced the deal Wednesday.As part of it, NovoNordisk also is making an equity investment (amount not disclosed) in Life Edit’s parent.“The advancements we’ve made to our next-generation gene editing platform and base editing capabilities are opening the next frontier of treating disease through DNA editing,” said Mitchell Finer, chief executive officer of Life Edit as well as president for research and development at ElevateBio. “Combining our Life Edit platform and the ability to make any edit anywhere with Novo Nordisk’s deep disease biology and engineering expertise will bring us closer to delivering potentially curative therapies for some of the world’s most challenging genetic diseases.”Here’s the skinny on the deal:Life Edit receives between $250 million and $335 million for as many as development programsThe company also has a chance to share in the profits of one programNovoNordisk is an investor in a $401 million funding round raised by Elevate BioPrograms to be pursued include rare genetic disorders and prevalent cardiometabolic diseases, the companies said.“Novo Nordisk will be responsible for all research and development costs and Life Edit is also eligible to receive tiered royalties on future net sales of therapeutic products,” Novo Nordisk said.“At Novo Nordisk, we are committed to continuously building and leveraging technology platforms that open up new opportunities across our therapeutic areas to deliver potentially curative treatment options to people living with serious chronic diseases,” said Marcus Schindler, PhD, professor, executive vice president and chief scientific officer of Novo Nordisk. “We are excited about the opportunity to co-create novel treatments for multiple genetic diseases based on Life Edit’s gene editing technologies.”
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Industries
Biotechnology
Healthcare
Company Size
51-200
Company Stage
N/A
Total Funding
N/A
Headquarters
Durham, North Carolina
Founded
2017
Find jobs on Simplify and start your career today