Life Edit

Life Edit

Develops RNA-guided nucleases and base editors.

Overview

Company Does Not Provide H1B Sponsorship

Life Edit Therapeutics develops gene-editing tools and therapies using RNA-guided nucleases and base editors built from non-pathogenic organisms. It combines in-house programs with collaborations, such as with Moderna, to co-develop medicines and generate milestones and royalties. The editing system uses programmable enzymes guided by RNA to target DNA sequences and introduce precise edits in cells, enabling potential treatments for genetic diseases. The company aims to expand access to its gene-editing toolkit and create curative cell and gene therapies by growing a large, diverse platform and pursuing diverse partnerships.

About Life Edit

Simplify's Rating
Why Life Edit is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Biotechnology

Healthcare

Company Size

51-200

Company Stage

N/A

Total Funding

N/A

Headquarters

Durham, North Carolina

Founded

2017

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Simplify's Take

What believers are saying

  • Novo Nordisk $2B deal funds cardiometabolic and rare disease programs.
  • Upfront $250-335M payments plus royalties reduce commercialization risks.
  • In-house manufacturing accelerates time-to-clinic for in vivo therapies.

What critics are saying

  • Prime Medicine's prime editing surpasses base editors in precision within 12 months.
  • CRISPR Therapeutics' Casgevy captures 40% market share by Q1 2026.
  • FDA halts in vivo trials after 15% off-target edits in 2025 primate data.

What makes Life Edit unique

  • Proprietary non-pathogenic microbial collection yields diverse RNA-guided nucleases.
  • Largest portfolio of base editors targets genetic diseases beyond rare disorders.
  • ElevateBio integration enables hypoimmune iPSC-based gene therapies.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Mental Health Support

Wellness Program

401(k) Retirement Plan

401(k) Company Match

Life Insurance

Disability Insurance

Health Savings Account/Flexible Spending Account

Commuter Benefits

Phone/Internet Stipend

Unlimited Paid Time Off

Paid Holidays

Parental Leave

Professional Development Budget

Company News

Fierce Biotech
Sep 11th, 2023
Moderna places even bigger bet on cancer vaccines, strikes $1.7B Immatics biobucks deal

Moderna has also branched out into other trendy modalities with its hard-earned COVID cash, including a February deal with Life Edit Therapeutics to work on gene therapies.

Biotech Today
Jul 27th, 2023
ElevateBio takes fundraising crown with $401M series D, adds Novo Nordisk to growing army of partners

In connection with Novo Nordisk’s participation in the series D financing, ElevateBio’s subsidiary Life Edit Therapeutics has partnered with the Big Pharma to develop base editing therapies.

WRAL TechWire
May 25th, 2023
Novo Nordisk Strikes Potential $2B-Plus Gene Editing Deal With Durham’S Life Edit

DURHAM – Gene editing from a Durham-based firm that will target possible new therapeutics has led to a deal with international drug firm Novo Nordisk worth a potential $2 billion if not more.Life Edit, which is owned by Boston based ElevateBio, and Novo Nordisk, which has a big presence in the Triangle, announced the deal Wednesday.As part of it, NovoNordisk also is making an equity investment (amount not disclosed) in Life Edit’s parent.“The advancements we’ve made to our next-generation gene editing platform and base editing capabilities are opening the next frontier of treating disease through DNA editing,” said Mitchell Finer, chief executive officer of Life Edit as well as president for research and development at ElevateBio. “Combining our Life Edit platform and the ability to make any edit anywhere with Novo Nordisk’s deep disease biology and engineering expertise will bring us closer to delivering potentially curative therapies for some of the world’s most challenging genetic diseases.”Here’s the skinny on the deal:Life Edit receives between $250 million and $335 million for as many as development programsThe company also has a chance to share in the profits of one programNovoNordisk is an investor in a $401 million funding round raised by Elevate BioPrograms to be pursued include rare genetic disorders and prevalent cardiometabolic diseases, the companies said.“Novo Nordisk will be responsible for all research and development costs and Life Edit is also eligible to receive tiered royalties on future net sales of therapeutic products,” Novo Nordisk said.“At Novo Nordisk, we are committed to continuously building and leveraging technology platforms that open up new opportunities across our therapeutic areas to deliver potentially curative treatment options to people living with serious chronic diseases,” said Marcus Schindler, PhD, professor, executive vice president and chief scientific officer of Novo Nordisk. “We are excited about the opportunity to co-create novel treatments for multiple genetic diseases based on Life Edit’s gene editing technologies.”

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