M

Mosaic Biosciences

Biotech firm: antibody discovery & development

Overview

Mosaic Biosciences discovers and develops therapeutic antibodies and protein drugs using its Phage Display and Yeast Display libraries, partnering with clients to move ideas from concept to preclinical candidate. It screens libraries against targets and then characterizes and optimizes lead molecules, supported by analytical services such as HPLC, interferometry, and plate-based assays to assess quality. The company differentiates itself with an integrated discovery-and-analytics platform and a collaborative, project-focused model rather than selling standalone tools. Its goal is to turn early concepts into viable drug candidates and accelerate therapeutic programs toward development.

Work here?Claim your company

About Mosaic Biosciences

Simplify's Rating
Why Mosaic Biosciences is rated
C+
Rated C on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

BiotechnologyHealthcare

Company Size

11-50

Company Stage

Early VC

Total Funding

$15.2M

Headquarters

Boulder, Colorado

Founded

2009

Get referred to Mosaic Biosciences

See people who can refer or advise you

Simplify Jobs

Simplify's Take

What believers are saying

  • September 8, 2026 Tessaic Nano expands addressable nanobody work without camelid immunization.
  • SortAI returns training-ready negative data within 14 weeks, matching AI drug-discovery budgets.
  • More than 216 completed discovery programs support commercialization and repeat-client conversion.

What critics are saying

  • Mosaic depends on CRO partnerships; Uniquity Bio and Elicit Plant concentration creates revenue fragility.
  • AI-antibody validation is crowded; better-funded CROs and internal pharma teams can compress pricing.
  • Negative business mix confusion from Mosaic Company search results muddies brand identity and hiring signal.

What makes Mosaic Biosciences unique

  • Tessaic Nano launched September 8, 2026, offering fully human in vitro VHH discovery.
  • SortAI, launched in 2026, validates AI-designed antibody libraries with yeast display and NGS.
  • Carterra HT-SPR, added March 26, 2026, deepens kinetics and epitope-binning workflows.

Help us improve and share your feedback! Did you find this helpful?

Funding

Total Funding

$15.2M

Meets

Industry Average

Funded Over

5 Rounds

Early VC funding comparison data is currently unavailable. We're working to provide this information soon!
Early VC Funding Comparison Coming Soon

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

4%

2 year growth

12%
Healthcare Industry Today
Sep 8th, 2026
Mosaic Biosciences launches Tessaic Nano, an in vitro VHH antibody library for rapid nanobody discovery.

Mosaic Biosciences launches Tessaic Nano, an in vitro VHH antibody library for rapid nanobody discovery. Fully human synthetic single-domain library expands Mosaic's VHH discovery capabilities alongside its in vivo partnership with Abkyu BOULDER, CO, UNITED STATES, September 8, 2026 / EINPresswire.com / - Mosaic Biosciences, a biologics discovery CRO focused on antibody and protein engineering, today announced the launch of Tessaic(TM) Nano, a fully human synthetic in vitro VHH library designed to accelerate nanobody discovery for clients across therapeutic, diagnostic, and research applications. Tessaic Nano is the first library released under Mosaic's Tessaic antibody library system, which also includes Tessaic Fab, a set of curated Fab-format libraries, near launch. The Nano library gives clients a fast, fully in-house route to single-domain candidates, requiring no humanization and no camelid immunization step. "Clients are increasingly running in vitro and in vivo VHH discovery in parallel to de-risk timelines and compare candidate profiles," said Tracey Mullen, Chief Strategy Officer at Mosaic Biosciences. "Tessaic Nano gives us a rapid, fully human option built entirely in-house, and it complements the work we do with Abkyu on the in vivo side. Together, these options let clients choose the discovery route that fits their program, or run both." Because Tessaic Nano is a fully human synthetic library, candidates emerge without the humanization step required for camelid-derived VHHs, shortening development timelines for programs headed toward the clinic. Along with donor derived CDRH3 diversity, Tessaic Nano incorporates curated diversity across CDRH1 and CDRH2, informed by internal repertoire analysis of which diversity placements have produced the strongest hit rates. Diversity is sourced from immune material captured and processed entirely in-house, and germlines are selected using literature-backed developability and pairing data, with liability filtering built into the design from the outset rather than addressed downstream. The library launch follows Mosaic's recent preferred partnership with Abkyu, a Boston-based in vivo VHH discovery specialist, giving Mosaic clients access to both in vitro and in vivo single-domain discovery routes under one program. Tessaic Nano is available now. Mosaic will be introducing the library at upcoming industry events, including Festival of Biologics Basel (October 13-15) and PEGS Europe (November 16-19). About Mosaic Biosciences Mosaic Biosciences is a Boulder, Colorado-based biologics discovery CRO offering integrated antibody discovery, protein engineering, and non-antibody therapeutic capabilities. Mosaic partners with biotech and pharma clients to deliver decision-grade candidates with predictable outcomes, from early discovery through developability. Chrissy Conti Mosaic Biosciences [email protected] Legal Disclaimer: EIN Presswire provides this news content "as is" without warranty of any kind. Healthcare Industry Today do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.

PR Newswire
Aug 17th, 2026
Mosaic Biosciences launches Renuvis Enzara to speed up crop residue breakdown

Mosaic Biosciences has launched Renuvis Enzara, a residue management solution using targeted enzyme technology to accelerate crop residue breakdown. The product addresses challenges from higher-yielding hybrids, no-till practices, and continuous corn that increase residue levels, potentially narrowing planting windows and reducing operational efficiency. Enzara uses endoglucanase enzyme technology that functions in temperatures as low as 32 degrees Fahrenheit, targeting structural fibres in crop residue. The solution can be applied in autumn or spring and is tank-mix compatible with existing fertiliser and herbicide applications. In 2025 on-farm trials, Enzara demonstrated improvements in residue decomposition in corn-on-corn and soybean-after-corn systems, with spring applications improving emergence, stand count, and uniformity in both crops. The product suits various production systems, including no-till, reduced-till, and conventional tillage operations.

Mosaic Biosciences
Aug 5th, 2026
Mosaic Biosciences and Uniquity Bio announce strategic collaboration in biologics development.

Mosaic Biosciences and Uniquity Bio announce strategic collaboration in biologics development. Mosaic Biosciences today announced a strategic collaboration with Uniquity Bio, a clinical-stage drug development company focused on immunology and inflammation. The collaboration brings together Mosaic's platform-agnostic biologics discovery expertise with Uniquity Bio's scientific rigor and clinical-stage pipeline to advance high-quality biologic candidates with the speed and precision that development programs demand. A science-first partnership. Uniquity Bio is a clinical-stage company backed by Blackstone Life Sciences, advancing therapeutic programs in immunology and inflammation with the standards of a global pharma company and the operational agility of a biotech. Its lead asset, solrikitug, is a highly potent monoclonal antibody targeting TSLP across multiple respiratory and gastrointestinal indications with significant unmet need. The collaboration pairs that clinical-stage ambition with Mosaic's integrated discovery model, spanning in vitro display, single B-cell methods, transgenic animal platforms, and emerging AI-enabled screening approaches, to support programs where biology, not platform availability, drives every decision. "We built Mosaic around the belief that the best discovery strategy is one tailored to the biology, not the platform. Uniquity Bio shares that science-first philosophy, and we're proud to support their mission to bring meaningful new medicines to patients." - Jean-Pierre Wery, CEO, Mosaic Biosciences What the collaboration delivers. The partnership combines Mosaic's deep expertise in biologics discovery and lead optimization with Uniquity Bio's focus on developing medicines for indications with significant unmet need. Together, the two organizations aim to move high-quality biologic candidates forward with the scientific depth and strategic coordination that clinical-stage programs require. "Mosaic brings a level of scientific depth and strategic partnership in support of clinical-stage and discovery programs that goes beyond traditional CRO relationships. Their integrated approach and broad discovery capabilities align well with how we think about advancing our pipeline." - Kiyomi Komori, VP of Translational Medicine, Uniquity Bio

Red River Farm Network
Jul 22nd, 2026
A new canola joint venture.

A new canola joint venture. Published Today Mosaic Biosciences and Elicit Plant announced the signing of a joint development agreement to identify and develop a new solution for canola for North America. Uding Elicit Plant's proprietary EliTerra technology platform, the program aims to identify and develop a new solution designed to help canola growers preserve yield potential under water-stress conditions.

Mosaic Biosciences
May 21st, 2026
Mosaic Biosciences launches SortAI, a wet lab validation service built for ai-designed antibody libraries.

Mosaic Biosciences launches SortAI, a wet lab validation service built for ai-designed antibody libraries. Mosaic Biosciences today announced the commercial launch of SortAI, a yeast display-based validation service designed specifically for AI-generated antibody sequence panels. SortAI enables AI drug discovery companies to screen model-derived libraries before committing to full recombinant protein production, returning structured experimental data that feeds directly back into model retraining. The bottleneck AI drug discovery can't ignore. Generative AI platforms are transforming antibody drug design, producing campaigns of hundreds of thousands to millions of computationally designed sequences per cycle. Yet the infrastructure built to validate those sequences was designed around traditional single-candidate drug programs: full recombinant expression on every sequence, one at a time. The result is a compounding problem: slow cycles, wasted production budget, and models that cannot improve until the wet lab catches up. Typical CROs produce and characterize whatever sequence list arrives in their inbox. SortAI filters it first. "Generative models can produce thousands of antibody candidates. Wet labs can validate a fraction of them. SortAI triages AI-generated libraries at scale so your best sequences get tested first and nothing falls through." - Eric Furfine, PhD, Chief Scientific Officer, Mosaic Biosciences One engagement. The full triage picture. SortAI delivers a complete triage picture in a single defined engagement: Binding, affinity, epitope binning, developability, and function together: A complete discovery funnel in a single engagement, with deliverables structured for model retraining rather than drug program documentation. Sequence liability review at intake: Mosaic scientists screen panels for CDR liabilities, aggregation motifs, poor expression signals, and other flags most AI algorithms don't account for. Bad sequences are removed before they waste wet lab capacity. Yeast-based selection at library scale: Multi-round selection across panels ranging from hundreds to over millions of sequences, with next-generation sequencing (NGS) at each round to track full population dynamics. Negative data returned as a deliverable: Every selection round generates a negative population. SortAI sequences and returns those alongside ranked positive binders - because what didn't bind is half the training signal. Function pulled forward: Candidates that pass binding are immediately pressure-tested through cell-based functional screening, before expensive downstream development work begins. Binding, affinity, epitope binning, developability, and function together: A complete discovery funnel in a single engagement, with deliverables structured for model retraining rather than drug program documentation. Faster cycles. A fraction of the cost. A production-centric competitor workflow covering binding and affinity alone requires approximately 7 weeks and costs significantly more than a full SortAI engagement, which extends through developability profiling and cell-based functional screening. Sequence enrichment for model training is available as early as 6 weeks from project initiation; a full engagement completes in approximately 14 weeks. The yeast display platform underpinning SortAI scales to 10[7] sequence diversity, three orders of magnitude beyond the throughput of production-centric validation workflows, enabling functional triage at the true scale of AI-generated libraries. "AI companies need data that makes the next design cycle better, not just data that's fast. SortAI is built on the principle that quality of signal matters more than speed of throughput, and that the two aren't mutually exclusive." - Tracey Mullen, Chief Strategy Officer, Mosaic Biosciences Built on demonstrated capability. SortAI is backed by Mosaic's team of 50+ scientists, 80% holding advanced degrees and more than 216 completed discovery programs. The yeast display workflow that powers SortAI has already demonstrated results in library-based screening engagements that competing CROs were unable to accommodate. The platform was first introduced publicly at PEGS Boston 2026 and is now available as a defined commercial service. Detailed pricing and scope information is available upon request under NDA. About Mosaic Biosciences. Mosaic Biosciences is a biologics discovery company specializing in antibody and protein engineering, with expertise spanning transgenic mouse platforms, display technologies, and multispecific antibody formats. Mosaic partners with biotech and pharmaceutical companies to generate high-quality, developable biologics optimized for real-world therapeutic success.

Recently Posted Jobs

Sign up to get curated job recommendations

There are no jobs for Mosaic Biosciences right now.

Find jobs on Simplify and start your career today

We update Mosaic Biosciences's jobs every few hours, so check again soon! Browse all jobs