NeuroPace

NeuroPace

Implantable brain-responsive neuromodulation for epilepsy

Overview

NeuroPace develops the RNS System, a brain-responsive neuromodulation device for treating refractory epilepsy. The implanted system monitors brain activity and delivers targeted electrical stimulation when abnormal patterns are detected to reduce seizures. Clinicians receive data and analysis to guide therapy, and the company sells devices with ongoing support. The goal is to broaden adoption, expand to other neurological disorders, and grow revenue while improving seizure control and quality of life for patients.

About NeuroPace

Simplify's Rating
Why NeuroPace is rated
B
Rated A on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Healthcare

Company Size

201-500

Company Stage

IPO

Headquarters

Mountain View, California

Founded

1999

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Simplify's Take

What believers are saying

  • Q1 2026 revenue hit $22.1M, up 8% YoY, with 2026 guidance raised to $101M.
  • NAUTILUS trial shows 18-month efficacy for generalized epilepsy at AES 2025.
  • $75M MidCap Financial facility funds RNS expansion since June 2025.

What critics are saying

  • GAAP net loss of $6.7M in Q1 2026 erodes cash, risks MidCap debt default.
  • Gross margins fell to 82.5% in Q1 2026 from inventory normalization.
  • FDA rejects Nautilus PMA post mid-cycle review, blocking IGE expansion.

What makes NeuroPace unique

  • RNS System is only FDA-approved device responding to brain activity like pacemaker for heart.
  • RNS System personalizes stimulation to unique brain patterns, preventing seizures pre-symptom.
  • RNS System provides intracranial EEG data fueling AI tools like SeizureID.

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Funding

Total Funding

$566M

Above

Industry Average

Funded Over

11 Rounds

Notable Investors:
Post IPO Debt funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Debt Funding Comparison
Coming Soon

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Health Savings Account/Flexible Spending Account

Paid Vacation

Paid Holidays

Remote Work Options

529 plan

Employee Stock Purchase Plan

Company Equity

Training Programs

Wellness Program

Commuter Benefits

Stock Price

Growth & Insights and Company News

Headcount

6 month growth

-2%

1 year growth

0%

2 year growth

0%
Yahoo Finance
Mar 4th, 2026
NeuroPace shares inch up 1% as Q4 revenue beats estimates at $26.6M

NeuroPace shares rose nearly 1% on Wednesday following its fourth-quarter earnings release. The medical device company reported revenue of $26.6 million, up 24% year-over-year and beating analyst estimates of $24.4 million. Its net loss narrowed to $2.7 million ($0.08 per share) from $5.3 million in the prior year, also surpassing expectations. Growth was driven by favourable Medicare reimbursement decisions and increased prescribers. Sales of the RNS System, an epilepsy treatment device that accounts for most revenue, rose 26% to over $22 million. The company maintained its full-year 2026 revenue guidance of $98 million to $100 million, with an adjusted EBITDA loss of $9 million to $10 million. The modest investor reaction likely reflects guidance that appears less impressive than quarterly growth.

Yahoo Finance
Mar 3rd, 2026
NeuroPace posts Q4 loss of $0.08 per share, beats revenue estimates with $26.59M

NeuroPace reported a quarterly loss of $0.08 per share, beating the Zacks Consensus Estimate of a $0.14 loss and representing a 41.48% earnings surprise. This compares to a loss of $0.18 per share a year ago. The medical instruments company posted revenues of $26.59 million for the quarter ended December 2025, surpassing estimates by 2.47%. This compares to year-ago revenues of $21.47 million. The company has topped consensus revenue estimates four times over the last four quarters. Despite the earnings beat, NeuroPace shares have declined 8.4% year-to-date versus the S&P 500's 0.5% gain. The company currently holds a Zacks Rank of 4 (Sell), suggesting expected underperformance in the near term.

The AI Journal Ltd
Dec 31st, 2025
NeuroPace to Present at the 44th Annual J.P. Morgan Healthcare Conference

NeuroPace to present at the 44th Annual J.P. Morgan Healthcare Conference. MOUNTAIN VIEW, Calif. - (BUSINESS WIRE) - NeuroPace, Inc. (Nasdaq: NPCE), a medical device company focused on transforming the lives of people living with epilepsy, today announced that its management team will present at the 44th Annual J.P. Morgan Healthcare Conference at 3:00pm PT on Wednesday, January 14, 2026, in San Francisco, CA. Management will also host investor meetings during the conference. The presentation will be accessible via live webcast here. A webcast replay will be available for thirty days following the presentation in the Events & Presentations section of NeuroPace's Investor website at https://investors.neuropace.com. Based in Mountain View, Calif., NeuroPace is a medical device company focused on transforming the lives of people living with epilepsy by reducing or eliminating the occurrence of debilitating seizures. Its novel and differentiated RNS System is the first and only commercially available, brain-responsive platform that delivers personalized, real-time treatment at the seizure source. This platform can drive a better standard of care for patients living with drug-resistant epilepsy and has the potential to offer a more personalized solution and improved outcomes to the large population of patients suffering from other brain disorders.

Investing News Network
Dec 2nd, 2025
NeuroPace to Highlight Life-Changing Outcomes and AI-Powered Confident Care at the 2025 American Epilepsy Society Annual Meeting

NeuroPace to highlight life-changing outcomes and ai-powered confident care at the 2025 American Epilepsy Society Annual Meeting. December 02, 2025 Neuropace, Inc. (Nasdaq: NPCE), a medical device company focused on transforming the lives of people living with epilepsy, today announced that its RNS System and Neuropace AI platform will be prominently featured at the 2025 American Epilepsy Society (AES) Annual Meeting in Atlanta, Georgia where Neuropace will feature new clinical and AI-driven advances that underscore the Company's focus on delivering life-changing outcomes and enabling physicians to provide more confident, data-informed care for people living with epilepsy. "Our presence at AES this year is about demonstrating life-changing, durable outcomes with the RNS System and how those outcomes are enabled by the depth and quality of our data," said Martha Morrell, MD, Chief Medical Officer at Neuropace. "New analyses for the RNS System Post-Approval Study for focal epilepsy, together with emerging results from the NAUTILUS study for idiopathic generalized epilepsy, demonstrate that responsive neuromodulation can deliver meaningful and sustained seizure reductions for patients. At the same time, the intracranial EEG data recorded by the RNS System is fueling AI-driven tools that help physicians treat with more confidence than ever before." In addition to long-term outcomes data, Neuropace will provide a first look at next-generation Neuropace AI and SeizureID(TM)[1] tools under development, which are being developed to transform intracranial EEG (iEEG) recordings into actionable insights that simplify epilepsy care. These tools are being designed to help clinicians review electrographic seizures, identify seizure patterns, and optimize RNS therapy programming - turning data into an asset that supports more confident decision-making at every visit. "RNS therapy uniquely combines best-in-class outcomes with a rich, longitudinal iEEG dataset," said Joel Becker, President and Chief Executive Officer of Neuropace. "Our strategy is to leverage that dataset - and our growing AI capabilities - to build a differentiated platform for epilepsy care. AES is an ideal venue to demonstrate how our evidence, our technology and our AI roadmap are coming together to set a new standard for responsive neuromodulation." Scientific and Educational Highlights at AES 2025 Key Neuropace-related presentations and activities planned for AES include: * New analyses from the RNS System PAS, including additional detail on seizure reduction durability at three years and beyond, and prolonged periods of GTC seizure freedom in many patients. * Multiple posters and presentations highlighting real-world outcomes and quality-of-life results across diverse drug-resistant focal epilepsy populations. * Updated data from the NAUTILUS clinical trial, the first and only study to evaluate responsive thalamic stimulation for the treatment of idiopathic generalized epilepsy (IGE), including 18-month safety and efficacy outcomes. * Demonstrations of Neuropace AI and SeizureID in the Neuropace booth and tech suite, illustrating how iEEG insights can streamline clinic workflows and support confident treatment decisions. * 11 Neuropace posters on the RNS System and more than 20 sessions featuring RNS therapy, underscoring Neuropace's commitment to generating high-quality evidence and advancing the understanding of neuromodulation for epilepsy. Product Theater - Transforming Epilepsy Care with the RNS System * Sunday, December 7, 2025 * 2:30 - 3:30 p.m. * Large Product Theater | Exhibit Hall, Georgia World Congress Center * Featured Speakers: * Martha Morrell, MD, FAES - Clinical Professor of Neurology, Stanford University; Chief Medical Officer, Neuropace * Kathryn Davis, MD, MSc, FAES - Associate Professor of Neurology, University of Pennsylvania; Director, Penn Epilepsy Center * Patricia Dugan, MD - Professor of Neurology, NYU Grossman School of Medicine; Director, Adult Epilepsy, NYU Langone Health * Session Focus: Eighteen-month outcomes from the NAUTILUS trial, including clinically meaningful seizure reductions in IGE, and an overview of how Neuropace is using AI to develop next-generation tools that advance epilepsy care. Discover How RNS System Therapy Can Strengthen Your Epilepsy Practice * Saturday, December 6, 2025 * Session Focus: Best practices from experienced RNS centers on clinic qualifications, patient selection and operational workflows for building a thriving responsive neuromodulation program. * Sunday, December 7, 2025 * Session Focus: Evolving strategies in network stimulation for focal epilepsy and how the RNS System is advancing the treatment of epilepsy. Throughout the meeting, members of the Neuropace team will be available at Booth #125 and in the Neuropace tech suite to provide hands-on demonstrations of the RNS System, Neuropace AI and SeizureID, and to discuss how to integrate responsive neuromodulation into clinical practice. Attendees can pre-book demonstrations and view a full list of Neuropace-related presentations at https://www.neuropace.com/december-conference-2025-epilepsy/. Based in Mountain View, Calif., Neuropace is a medical device company focused on transforming the lives of people living with epilepsy by reducing or eliminating the occurrence of debilitating seizures. Its novel and differentiated RNS System is the first and only commercially available, brain-responsive platform that delivers personalized, real-time treatment at the seizure source. This platform can drive a better standard of care for patients living with drug-resistant epilepsy and has the potential to offer a more personalized solution and improved outcomes to the large population of patients suffering from other brain disorders. This press release may contain forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements may be identified by words such as "aims," "anticipates," "believes," "could," "estimates," "expects," "forecasts," "goal," "intends," "may," "plans," "possible," "potential," "seeks," "will" and variations of these words or similar expressions that are intended to identify forward-looking statements, although not all forward-looking statements contain these words. Neuropace may not actually achieve the plans, intentions or expectations disclosed in these forward-looking statements, and you should not place undue reliance on these forward-looking statements. Forward-looking statements in this press release include, but are not limited to, statements regarding: Neuropace's expectations, forecasts and beliefs with respect to potential indication expansion for its RNS System and its software, technology and other product development efforts; increasing access to and adoption of RNS therapy as the standard of care in drug-resistant epilepsy; the impact that its new product development, including AI-based software suite, Neuropace AI(TM) and Seizure ID(TM), will bring to patients and physicians who prescribe the RNS System. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements as a result of various factors, including: actual operating results may differ significantly from any guidance provided; uncertainties related to market acceptance and adoption of Neuropace's RNS System; risks related to regulatory compliance and expectations for regulatory submissions and approvals to expand the market for Neuropace's RNS System, including risks related to the NAUTILUS clinical trial; risks related to product development, including risks related to the development of AI-powered software, including Neuropace AI(TM) and Seizure ID(TM) and the next generation device platform; risks related to Neuropace's reliance on contractors and other third parties, including single-source suppliers and vendors; and other important factors. These and other risks and uncertainties include those described more fully in the section titled "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" and elsewhere in Neuropace's public filings with the U.S. Securities and Exchange Commission (SEC), including its Quarterly Report on Form 10-Q for the quarter ended September 30, 2025, filed with the SEC on November 4, 2025, as well as any other reports that it may file with the SEC in the future. Forward-looking statements contained in this announcement are based on information available to Neuropace as of the date hereof. Neuropace undertakes no obligation to update such information except as required under applicable law. These forward-looking statements should not be relied upon as representing Neuropace's views as of any date subsequent to the date of this press release and should not be relied upon as a prediction of future events. In light of the foregoing, investors are urged not to rely on any forward-looking statement in reaching any conclusion or making any investment decision about any securities of Neuropace. View source version on businesswire.com: https://www.businesswire.com/news/home/20251202649264/en/

Investors Hangout
Jun 4th, 2025
NeuroPace Secures $75M for Epilepsy Treatment

NeuroPace, Inc. has secured a $75 million credit facility from MidCap Financial, comprising a $60 million term loan and a $15 million revolving credit facility. This funding will repay a previous loan and support growth initiatives, including expanding access to their RNS System for epilepsy treatment. The partnership aims to enhance NeuroPace's financial management and patient outreach, with a focus on innovation and improving patient care.

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