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Overview
NewLimit develops medicines that aim to extend healthy years by reprogramming the epigenome of aging cells. It works by identifying aging-related epigenetic changes using single-cell genomics, machine learning, and high-throughput functional assays, then creating interventions to reverse those changes in targeted tissues such as the immune system and liver. Compared with others, NewLimit combines a specific focus on epigenetic reprogramming with a data-driven, tissue-targeted pipeline and pursues partnerships with pharma and biotech players to develop its proprietary medicines. Its goal is to deliver a new class of medicines that significantly increases the healthspan for patients with age-related diseases.
About NewLimit
Industries
Biotechnology
Healthcare
Company Size
51-200
Company Stage
Series C
Total Funding
$650M
Headquarters
South San Francisco, California
Founded
2022
Simplify's Take
What believers are saying
- $435 million Series C funds clinical entry and computational expansion.
- Lead liver program targets alcohol-related liver disease with clear translational endpoints.
- Platform expansion into immune and vascular cells broadens addressable aging indications.
What critics are saying
- First-in-human liver reprogramming data arrive late, extending validation uncertainty.
- Epigenetic reprogramming can trigger tumorigenicity or permanent cell-identity loss.
- Lipid nanoparticle RNA delivery can fail before biology reaches human cells.
What makes NewLimit unique
- AI-guided transcription factor screening compresses reprogramming discovery cycles.
- Lead liver program uses lipid nanoparticle RNA medicines for transient expression.
- Single-cell genomics and functional assays form an iterative closed-loop platform.
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Funding
Total Funding
$650M
Above
Industry Average
Funded Over
4 Rounds
Kleiner Perkins
Founders FundIndustry standards
Benefits
Health Insurance
Dental Insurance
Vision Insurance
401(k) Retirement Plan
401(k) Company Match
Paid Parental Leave
Unlimited Paid Time Off
Growth & Insights and Company News
6 month growth
↑ 2%1 year growth
↑ 2%2 year growth
↑ 2%NewLimit, an anti-aging startup founded in 2021 by Coinbase CEO Brian Armstrong, has raised $45 million in new funding, valuing the company at $1.62 billion. The round comes just five months after its Series B, demonstrating rapid growth and strong investor confidence. The company focuses on extending human healthspan by treating age-related diseases. The fresh capital will support groundwork for future clinical studies to advance its technological capabilities. Competition in the longevity sector is intensifying, with OpenAI CEO Sam Altman investing $180 million in rival Retro Biosciences. Despite a 2025 downturn in anti-aging research stocks, NewLimit's successful funding round highlights investor belief in the sector's long-term potential and suggests continued capital flow into this emerging market.
Five months after closing our Series B, NewLimit has raised an additional $45M from Eli Lilly and Company, Duke Management Co, Section 32, and others on a $1.62B cap.
NewLimit, an anti-aging biotech startup co-founded by a cryptocurrency billionaire, has raised $45 million from new investors, including Eli Lilly. This funding positions NewLimit to potentially become biotech's latest unicorn.
NewLimit has successfully raised $129.8 million in equity financing from a total offering amount of $130 million.
NewLimit is developing medicines to extend human healthspan through epigenetic reprogramming
NewLimit is Hiring for 11 Jobs on Simplify!
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About NewLimit
Industries
Biotechnology
Healthcare
Company Size
51-200
Company Stage
Series C
Total Funding
$650M
Headquarters
South San Francisco, California
Founded
2022
NewLimit is Hiring for 11 Jobs on Simplify!
Find jobs on Simplify and start your career today