Output Biosciences

Output Biosciences

AI-driven preventative therapeutics for chronic disease

Overview

Output Biosciences develops preventative therapeutics to extend human healthspan by combatting chronic diseases. It uses computational biology and AI to discover therapies that can prevent diseases faster, with safer profiles and easier manufacturing, enabling quicker development timelines. The company differentiates itself by integrating biotech expertise with AI to create therapies focused on prevention, and by forming partnerships with pharmaceutical companies, licensing its technologies, and pursuing direct therapy sales. Its goal is to bring preventive treatments to market within months, shifting drug development toward stopping chronic diseases before they start.

YC Company

About Output Biosciences

Simplify's Rating
Why Output Biosciences is rated
D+
Rated D+ on Competitive Edge
Rated D+ on Growth Potential
Rated D+ on Differentiation

Industries

AI & Machine Learning

Biotechnology

Healthcare

Company Size

1-10

Company Stage

Seed

Total Funding

$130K

Headquarters

New York City, New York

Founded

2020

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Simplify's Take

What believers are saying

  • The July 28, 2026 website says it is still hiring, signaling active execution.
  • LinkedIn jobs in June 2026 listed interpretability and molecular-generation roles, showing technical expansion.
  • Its AI-biology positioning fits investors chasing faster discovery and easier manufacturing.

What critics are saying

  • Funding looks tiny: PitchBook shows $125K raised, and CB Insights shows $500K total.
  • No public clinical asset, partnership, or revenue evidence exists by July 2026.
  • An AI-platform story without drug candidates risks commoditization before meaningful validation.

What makes Output Biosciences unique

  • Output Bio's 2026 website sells biologically-aware generative AI for breakthrough medicines.
  • It targets long, nonlinear biological data with Large Biological Models, not standard chemistry pipelines.
  • Mirella Mashiach has led the company since July 2021, signaling founder continuity.

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Funding

Total Funding

$130k

Below

Industry Average

Funded Over

1 Rounds

Notable Investors:
Seed funding is usually the first official round after pre-seed, when a startup has a prototype or concept. It’s typically used to develop the product, test the market, and start building the team. Investors here are often angel investors or early-stage venture capitalists.
Seed Funding Comparison
Below Average

Industry standards

$3.3M
$130k
Output Biosciences
$1.5M
Slack
$2M
Netflix
$2.3M
Instacart
$3M
Robinhood

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Company Equity

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Output Biosciences is Hiring for 9 Jobs on Simplify!

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