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Industries
AI & Machine Learning
Biotechnology
Healthcare
Company Size
201-500
Company Stage
Series B
Total Funding
$325.9M
Headquarters
Paris, France
Founded
2016
Owkin specializes in using artificial intelligence to improve diagnostics and drug development in healthcare. The company employs machine learning techniques and biological data to make clinical trials more efficient and less risky, which helps speed up the process of bringing new drugs to market. Owkin works with major biopharma companies and academic institutions, providing AI solutions that fit into existing digital pathology systems for better diagnosis. Unlike many competitors, Owkin focuses on creating custom AI models and using various types of patient data to improve clinical trial recruitment and results. The main goal of Owkin is to enhance the effectiveness of drug development and diagnostics, particularly in oncology and other serious diseases.
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Total Funding
$325.9M
Above
Industry Average
Funded Over
5 Rounds
Industry standards
What You Should Know:– Owkin, an AI-powered biotech company, today announced the dosing of the first patient in its Phase I clinical trial of OKN4395, a novel cancer therapy designed to restore immune function in patients with advanced solid tumors.– OKN4395 represents a novel approach to cancer treatment by targeting multiple immunosuppressive pathways simultaneously.OKN4395 BackgroundOKN4395 is a first-in-class asset that selectively inhibits three immunosuppressive receptors: EP2, EP4, and DP1. These receptors are known to play a role in tumor progression and resistance to immunotherapy. By blocking these pathways, OKN4395 aims to unleash the power of the immune system to fight cancer.The INVOKE Study (OKN-4395-121)The Phase Ia/1b clinical trial, known as INVOKE, is a global, multicenter, open-label study evaluating OKN4395 in patients with advanced solid tumors.Phase Ia: Assesses the safety and tolerability of OKN4395 as a monotherapy and in combination with pembrolizumab (an immunotherapy drug).Assesses the safety and tolerability of OKN4395 as a monotherapy and in combination with pembrolizumab (an immunotherapy drug). Phase Ib: Expands into four cohorts to evaluate preliminary anti-tumor activity, safety, and conduct extensive exploratory analyses.Owkin’s proprietary K1.0 Operating System played a crucial role in the development of OKN4395, from asset selection to clinical trial design. The AI platform was used to:Gain a deeper understanding of the target pathways: Analyze complex biological data to identify and validate the EP2/EP4/DP1 targets.Analyze complex biological data to identify and validate the EP2/EP4/DP1 targets. Optimize indication selection: Identify the most promising cancer types for OKN4395 treatment.Identify the most promising cancer types for OKN4395 treatment
Owkin, an end-to-end AI-biotech has announced Owkin K1.0 - a proprietary operating system (OS) for discovering new disease biology with the goal to become the first Artificial General Intelligence (AGI) for biology.
VANCOUVER, Wash. and PARIS, Jan. 10, 2025 (GLOBE NEWSWIRE) -- Absci Corporation (NASDAQ: ABSI), a data-first generative AI drug creation company, and Owkin, a TechBio that uses agentic AI to unlock complex targets for drug discovery, development, and diagnostics, today announced a partnership bringing together two leading AI platforms to rapidly discover and design novel therapeutics for patients. “At Absci, we’re constantly pushing the boundaries of innovation to bring better biologics to patients faster,” said Sean McClain, Founder and CEO of Absci. “By combining Absci’s AI de novo design expertise with Owkin’s world-class predictive AI target discovery technology, we have a unique opportunity to design first-in-class and potentially transformative therapeutics for patients in need.” Through this strategic partnership, Absci and Owkin will co-develop therapeutic candidates addressing novel targets in immuno-oncology and other indications, such as immunology and inflammation. Owkin’s predictive AI models will optimize target selection and validate therapeutic hypotheses using extensive biomedical datasets and patient-derived organoids
What You Should Know:– Owkin, an AI-biotech company specializing in precision medicine, and Proscia, a leader in AI-enabled pathology solutions, have announced a strategic partnership to improve MSI testing for colorectal cancer (CRC). This collaboration aims to enhance the efficiency and accessibility of MSI screening, ultimately leading to better patient outcomes.– Beyond MSI testing, Owkin and Proscia plan to collaborate on developing and commercializing additional AI solutions for research and diagnosis in oncology.The Importance of MSI Testing in Colorectal CancerMSI (Microsatellite Instability) is a genomic biomarker found in a significant portion of colorectal cancer patients. It plays a crucial role in guiding treatment decisions, as patients with MSI-high tumors often respond well to immunotherapy and may not benefit from traditional chemotherapy.Challenges in MSI TestingWhile universal MSI screening is recommended for CRC patients, current testing methods face challenges:Cost: Traditional methods like IHC, PCR, and NGS can be expensive.Traditional methods like IHC, PCR, and NGS can be expensive. Accessibility: Access to these tests may be limited in certain regions or healthcare settings.Access to these tests may be limited in certain regions or healthcare settings. Tissue Consumption: These tests can require significant amounts of tissue, which may be limited in some cases.These tests can require significant amounts of tissue, which may be limited in some cases. Interpretation: Results can sometimes be subjective and require expert interpretation.AI-Powered Solution for MSI ScreeningOwkin’s MSIntuit CRC v2 is an AI-powered solution designed to address these challenges
Owkin, the first end-to-end AI-biotech that uses cutting-edge causal AI to unlock precision drug discovery, development, and diagnostics has announced MSIntuit(R) CRC v2[1], a next-generation AI solution.
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Industries
AI & Machine Learning
Biotechnology
Healthcare
Company Size
201-500
Company Stage
Series B
Total Funding
$325.9M
Headquarters
Paris, France
Founded
2016
Find jobs on Simplify and start your career today