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Phenome Health

Nonprofit research enabling early disease intervention

Overview

Phenome Health is a nonprofit research organization working to extend the number of healthy years people have. It shifts healthcare from just treating disease to predicting and preventing it, using data from multiple biological sources and deep phenotyping. It collects and integrates genomics, proteomics, metabolomics, and other omics data, applies analytics to find early disease signals, and creates tools for earlier, personalized intervention. Its goal is to widen healthy lifespans by enabling earlier, tailored prevention and care.

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About Phenome Health

Simplify's Rating
Why Phenome Health is rated
C+
Rated B on Competitive Edge
Rated B on Growth Potential
Rated D+ on Differentiation

Industries

Data & AnalyticsHealthcare

Company Size

1-10

Company Stage

N/A

Total Funding

N/A

Headquarters

Washington, United States

Founded

2021

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What believers are saying

  • Phenome Health says it won over $50 million in federal and state awards since 2024.
  • Phenome Health launched a 2026 open-data push for clinically validated actionable possibilities.
  • Lee Hood's 2026 talks keep recruiting attention from academia and government funders.

What critics are saying

  • Phenome Health still depends on Hood's fundraising network, not product revenue.
  • The 2023 Buck partnership remains research-heavy, with no commercialized platform disclosed.
  • If federal grants slow, the one-million-person moonshot stalls before clinical utility.

What makes Phenome Health unique

  • Leroy Hood's phenome platform integrates genomes, EHRs, wearables, biopsies, and AI.
  • Buck Institute partnership gives Phenome Health geroscience labs and animal-model validation since 2023.
  • The Human Phenome Initiative targets one million longitudinal participants, a rare scale in longevity science.

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Company News

GenomeWeb
Apr 25th, 2025
HudsonAlpha Launches Pilot Project to Study Genetics, Lifestyle of Alzheimer's Disease

NEW YORK - The HudsonAlpha Institute for Biotechnology said Friday that it is collaborating with Phenome Health and the Buck Institute for Research in Aging on a pilot study to examine how genetics and lifestyle influence a person's risk of developing Alzheimer's disease.

GeekWire
Sep 27th, 2023
Genomics Pioneer Lee Hood Joins Forces With The Buck Institute To Study Aging And Disease

Leroy Hood, CEO of Phenome Health and co-founder of the Institute for Systems Biology will co-lead a new center at the Buck Institute for Research on Aging. (Phenome Health Photo). Phenome Health, a Seattle research organization dedicated to what it calls a data-driven approach to human health and longevity, launched a partnership Wednesday with the Buck Institute for Research on Aging, based in Novato, Calif. The partnership establishes the Center for Phenomic Health at the Buck Institute, under the co-leadership of Buck CEO Eric Verdin and Seattle bioscience pioneer Leroy Hood. Hood founded Phenome Health in 2021 with the aim of understanding aging and detecting disease early by collecting multiple biological data points in individuals. That approach syncs up with the Buck Institute’s aim of extending human “healthspan,” the number of years of healthy aging, Hood told GeekWire

GeekWire
Apr 29th, 2023
Ai And The Future Of Human Health: Leroy Hood On The New Age Of ‘Scientific Wellness’

AI will help make it possible “to take each individual and map out exactly how they should optimize their health and keep track of it,” says Leroy Hood, a life sciences leader known for his past role in developing automated methods for sequencing DNA. (GeekWire File Photo / Dan DeLong)Biomedicine pioneer Leroy Hood says that artificial intelligence will play a key role in the future of healthcare by accelerating the progress of “scientific wellness,” an approach that he has championed for many years. Hood, co-founder of the Institute for Systems Biology, delves into this approach in his new book, “The Age of Scientific Wellness,” which he wrote with co-author Nathan Price, an ISB professor and chief scientific officer of Thorne HealthTech.On this week’s GeekWire Podcast, we talk with Hood about the book, how AI is key to the future of medicine, and what people can do now to live a healthy life. “AI will be the core foundation for the diagnosis and delivery of actionable possibilities for the information that comes from data-driven health in the future,” he said. “It will be able to take each individual and map out exactly how they should optimize their health and keep track of it.”The book explores the notion that, at some point during life, every person makes a transition from wellness to nascent disease. It might not be something we see, feel, or can sense

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