Pierre Fabre

Pierre Fabre

Allogeneic cell therapies development and commercialization

Overview

Pierre Fabre Pharmaceuticals (US) develops and commercializes allogeneic cell therapies for oncology and rare diseases. It focuses on bringing next-generation, donor-derived cell therapies to patients with high unmet medical needs and deepens partnerships with biotech companies to advance products through clinical manufacturing and distribution in the US.

Significant Headcount Growth

About Pierre Fabre

Simplify's Rating
Why Pierre Fabre is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Biotechnology

Healthcare

Company Size

5,001-10,000

Company Stage

Seed

Total Funding

$13.8M

Headquarters

Toulouse, France

Founded

1951

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Simplify's Take

What believers are saying

  • European Commission approved BRAFTOVI plus cetuximab and FOLFOX for first-line BRAFV600E mCRC.
  • Pierre Fabre integrated Vertical Bio, adding exarafenib and a pan-RAF program in 2026.
  • Salesforce adopted Agentforce for 4,000 users, signaling stronger global commercial execution and data unification.

What critics are saying

  • FDA issued a January 9, 2026 CRL for tabelecleucel; U.S. launch slips again.
  • Northern California denied Pierre Fabre’s motion to dismiss Avène preservative-labeling claims in April 2026.
  • Pierre Fabre’s oncology value hinges on BRAF assets; an EU setback would crush pipeline momentum.

What makes Pierre Fabre unique

  • Pierre Fabre’s Foundation controls 86.3%, preserving independence and long-term capital allocation.
  • The company spans oncology, rare disease, and dermocosmetics, diversifying scientific and commercial channels.
  • Its 2026 pipeline combines approved BRAFTOVI assets with acquired exarafenib and tabelecleucel.

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Funding

Total Funding

$13.8M

Above

Industry Average

Funded Over

1 Rounds

Seed funding is usually the first official round after pre-seed, when a startup has a prototype or concept. It’s typically used to develop the product, test the market, and start building the team. Investors here are often angel investors or early-stage venture capitalists.
Seed Funding Comparison
Above Average

Industry standards

$3.3M
$2M
Netflix
$2.3M
Instacart
$3M
Robinhood
$13.8M
Pierre Fabre

Benefits

Health Insurance

Paid Holidays

Paid Vacation

Company Equity

Profit Sharing

Remote Work Options

Commuter Benefits

Growth & Insights and Company News

Headcount

6 month growth

6%

1 year growth

6%

2 year growth

6%
PR Newswire
Aug 25th, 2026
Laboratoires Pierre Fabre appoints Nicolas Zombré CEO of U.S. Dermocosmetics business, signaling next phase of growth.

Laboratoires Pierre Fabre appoints Nicolas Zombré CEO of U.S. Dermocosmetics business, signaling next phase of growth. Aug 25, 2026, 13:19 ET SECAUCUS, N.J., Aug. 25, 2026 /PRNewswire/ - Laboratoires Pierre Fabre, the world's second-largest dermo-cosmetics company and one of Europe's leading pharmaceutical groups, announced today the appointment of Nicolas Zombré as Chief Executive Officer of its U.S. Dermocosmetics operations. In this role, Zombré will oversee the company's U.S. dermocosmetics business across its portfolio of brands, including Avène, René Furterer and Klorane, as Pierre Fabre continues to build momentum in the U.S. market. This appointment reflects Pierre Fabre's continued investment in expanding its U.S. footprint across retail, medical and digital channels. Avène has emerged as one of the fastest-growing dermocosmetics brands in the U.S., delivering double-digit year-over-year growth and building strong retail momentum with leading partners including Amazon, CVS, Target, Ulta, Walgreens and, most recently, Walmart. This growth has been fueled by continued consumer demand for effective, scientifically proven skincare across Avène's core categories, with Cicalfate+ Restorative Protective Cream delivering standout growth of +32%. Retinal 0.1 Intensive Multi-Corrective Cream, Tolerance Control Skin Recovery Cream, and the new Tolerance Facial Foaming Cleanser have also contributed to the brand's continued growth. Zombré will bring his global leadership experience and omnichannel expertise to further scale the business. Zombré brings nearly two decades of leadership experience within Pierre Fabre. He began his career at Pierre Fabre Dermo-Cosmétique in France in 2006 as a Product Manager for Galénic and Klorane, later taking on trade marketing responsibilities for major pharmacy accounts in France. In 2013, he moved to Brazil to lead National Sales and Trade Marketing and was subsequently promoted to Commercial Director, expanding his international go-to-market experience across diverse business models. From 2018 to 2020, Zombré served as General Manager of Pierre Fabre Dermocosmétique in Chile, where he focused the affiliate's strategy on consumer centricity and digitalization. In June 2020, he was appointed General Manager of Pierre Fabre's dermocosmetics division in Spain and later assumed leadership of Pierre Fabre Pharma Spain, overseeing brands including A-Derma, Ducray, Eau Thermale Avène, Klorane and René Furterer. Most recently, he served as General Director of Pierre Fabre in Spain, leading the affiliate's transformation across omnichannel strategy, retail excellence and value-added services for pharmacy, e-retail and physician partners. "Nicolas has a proven track record of driving transformation across some of our most dynamic markets, and he joins at a pivotal moment for Pierre Fabre in the U.S.," said Eric Ducournau, CEO of Laboratoires Pierre Fabre. "His experience leading digital and omnichannel strategy abroad gives him exactly the expertise we need to accelerate our growth and strengthen our position as a leader in dermocosmetics." "I'm honored to take on this role at such an exciting moment for Pierre Fabre in the U.S.," said Nicolas Zombré, CEO of Laboratoires Pierre Fabre U.S. "Our brands have built deep trust with consumers and healthcare professionals, and I see tremendous opportunity to build on that foundation by strengthening those relationships, expanding our presence across retail and digital channels, and continuing to lead with the science and credibility our portfolio is known for. I look forward to working with the U.S. leadership to write this next chapter." Zombré's appointment marks the next step in Pierre Fabre's long-term strategy to strengthen its presence in the U.S. market, one of the company's key growth priorities globally. Note: High-resolution images, interviews, and product samples are available upon request. ABOUT LABORATOIRES PIERRE FABRE Laboratoires Pierre Fabre is the world's second-largest dermo-cosmetics company and one of Europe's leading pharmaceutical laboratories. Its Dermo-cosmetics & Personal Care portfolio brings together major international brands such as Eau Thermale Avène, Dexeryl, Ducray, Klorane, A-Derma, René Furterer, Même Cosmetics, Darrow, and Elgydium. The Pharma activity covers 5 main therapeutic fields: oncology, dermatology, rare diseases, primary care and family health care. In 2025, Laboratoires Pierre Fabre generated €3.2 billion euros in revenue, 71% of which came from international sales across 130 territories. Based in southwest France since its creation and manufacturing nearly 90% of its products in France, Laboratoires Pierre Fabre employs 10,000 people worldwide. R&D investments increased by 14% compared with the previous year, reaching €250 million, 67% of which is dedicated to targeted therapies in oncology. The majority shareholder of Laboratoires Pierre Fabre is the Pierre Fabre Foundation (holding 86.3% of the capital), a humanitarian foundation recognized as being of public utility. The company's employees are its second-largest shareholder (nearly 10%). This shareholding structure guarantees the company's independence, its long-term vision and its sustainable contribution to the common good. Dividends paid to the Pierre Fabre Foundation contribute to 35 healthcare-access programs deployed in 22 of the least developed countries in the world. Since 2023, Laboratoires Pierre Fabre' CSR policy has been assessed by AFNOR Certification and has been awarded the "Exemplary" level of its CSR label (ISO 26 000 standard for sustainable development). For more information, visit www.pierre-fabre.com SOURCE Laboratoires Pierre Fabre

PR Newswire
Jun 22nd, 2026
EU approves BRAFTOVI combo as first targeted therapy for BRAFV600E-mutant mCRC first-line treatment

Laboratoires Pierre Fabre has received European Commission approval for BRAFTOVI (encorafenib) in combination with cetuximab and FOLFOX for first-line treatment of adult patients with BRAFV600E-mutant metastatic colorectal cancer. This marks the first and only combination with a BRAF-targeted therapy approved for this indication in the EU. The approval follows results from the Phase 3 BREAKWATER trial, which showed the combination achieved statistically significant improvements in dual primary endpoints. Median progression-free survival reached 12.8 months versus 7.1 months for oxaliplatin-based chemotherapy with or without bevacizumab. The treatment reduced the risk of death by 51% and demonstrated a confirmed objective response rate of 65.7% compared to 37.4% in the control group. The regimen addresses a significant unmet need for patients with limited treatment options.

Salesforce
May 21st, 2026
Laboratoires Pierre Fabre selects Agentforce Life Sciences for Customer Engagement to transform medical and dermo-cosmetic care.

Laboratoires Pierre Fabre selects Agentforce Life Sciences for Customer Engagement to transform medical and dermo-cosmetic care. CASTRES, France, and SAN FRANCISCO - May 21, 2026 - Laboratoires Pierre Fabre, a major global pharmaceutical and dermo-cosmetics company based in France, has selected Agentforce Life Sciences for Customer Engagement for its more than 4,000 internal users to harmonize its commercial processes across its prescription drug and dermo-cosmetic business lines into a single platform as "One CRM." Building on an existing foundation of Agentforce Service and Data 360, the French company is expanding its Salesforce footprint to break down existing silos between its medical and dermo-cosmetics (OTC) businesses, including global brands such as Eau Thermale Avène or Klorane. The Agentforce 360 Platform will serve as its single, next-generation operating system covering all medical and point-of-sale (POS) related processes across the organization's global operations. This harmonized and regulation-compliant approach will help to ensure consistent and personalized engagement across channels and improve healthcare experiences and access. * Omni-Channel Synergy: Powered by Data 360 and Agenforce Marketing, the company will gain holistic stakeholder views for AI-guided engagement and synchronized interactions across medical and dermo-cosmetics, facilitating personalized journeys for HCPs, key opinion leaders (KOLs), and pharmacies alike. * Personalized Medical Engagement: Agentforce Life Sciences will coach, prepare, and log healthcare visits, updating records to maintain compliance and help to reduce the administrative burden on medical science liaisons (MSLs) and med reps. Through improved content alignment with clinical expectations and a more consistent physical and digital experience, Pierre Fabre aims to improve HCP satisfaction by up to 20%. * Optimized Retail Execution: Agentforce 36O for Life Sciences will help to boost sell-in, maximize sell-out, and drive POS excellence, including rebates, vouchers, and discounting, worldwide. With automated and accurate order management, the dermo-cosmetics leader will improve both care experiences and revenue, taking into account the complexities of country-specific sales rules and pricing structures. Marie-Andrée Gamache, CEO of Pierre Fabre Pharma, explained: "Salesforce will enable us to have a truly customer-centric view by bringing together our two businesses onto a single platform. We will be realizing our vision of a truly harmonized, next-generation operating system. This transformation will allow our teams to act as one cohesive health and dermo-cosmetic player, whether engaging a specialist on oncology therapies or a pharmacist on our dermo-cosmetic products. We chose Agentforce Life Sciences because it provides the robust, proven, and flexible foundation required to simplify our operations while supporting the unique complexity of our global, dual-business model." Emilie Sidiqian, CEO of Salesforce France, added: "We are delighted to partner with Laboratoires Pierre Fabre on this enterprise-wide commercial transformation. This collaboration underscores Agentforce Life Science's market leadership and commitment to delivering the innovative, industry-specific solutions required to meet the evolving needs of global sciences companies. We are proud to provide Laboratoires Pierre Fabre with the trusted platform to break down data silos, enhance customer engagement, and further their mission of improving human health and well-being through their unique blend of prescription medicine and consumer care." About Laboratoires Pierre Fabre. Pierre Fabre Laboratories is the world's second-largest dermo-cosmetics company and one of Europe's leading pharmaceutical laboratories. Its Dermo-cosmetics & Personal Care portfolio brings together major international brands such as Eau Thermale Avène, Dexeryl, Ducray, Klorane, A-Derma, René Furterer, Même Cosmetics, Darrow, and Elgydium. The Pharma activity covers five main therapeutic fields: oncology, dermatology, rare diseases, primary care, and family healthcare. In 2025, Pierre Fabre Laboratories generated 3.2 billion euros in revenue, 71% of which came from international sales across 130 territories. Based in southwest France since its creation and manufacturing nearly 90% of its products in France, Pierre Fabre Laboratories employs 10,000 people worldwide. R&D investments increased by 14% compared with the previous year, reaching 250 million euros, 67% of which is dedicated to targeted therapies in oncology. The majority shareholder of Pierre Fabre Laboratories is the Pierre Fabre Foundation (holding 86.3% of the capital), a humanitarian foundation recognized as being of public utility. The company's employees are its second-largest shareholder (nearly 10%). This shareholding structure guarantees the company's independence, its long-term vision, and its sustainable contribution to the common good. Dividends paid to the Pierre Fabre Foundation contribute to 35 healthcare-access programs deployed in 22 of the least-developed countries in the world. Since 2023, Pierre Fabre Laboratories' CSR policy has been assessed by AFNOR Certification and has been awarded the "Exemplary" level of its CSR label (ISO 26000 standard for sustainable development). About Salesforce. Salesforce helps organizations of all sizes become Agentic Enterprises, integrating people, agents, applications, and data on a unified, trusted platform to drive unprecedented growth and innovation. Visit www.salesforce.com/fr to learn more. Just for you.

PR Newswire
Mar 11th, 2026
Avène uses AI to expand acne clinical study from 100 to 600 patients

Pierre Fabre Laboratories' brand Avène is using artificial intelligence to enhance clinical studies for acne treatments. In partnership with Toulouse-based HealthTech company BotDesign, the brand is employing data augmentation to expand patient data from 100 to 600 participants, strengthening the robustness of its research. In 2026, Avène will conduct a comparative clinical study evaluating its new treatment, Cleanance Comedomed+, for acne-prone skin in the maintenance phase following oral isotretinoin treatment in adults with severe to very severe acne. The initiative represents a breakthrough in dermo-cosmetics clinical studies, allowing the leading French pharmacy brand to support more patients whilst improving research quality through AI-powered data enhancement.

Top Class Actions
Dec 19th, 2025
Class action claims Avène products falsely advertised as '0% preservative'

Class action claims Avène products falsely advertised as '0% preservative' Edited by: top class actions | december 19, 2025. Pierre Fabre class action lawsuit overview: * Who: Plaintiff Ivy-Karina Vales filed a class action lawsuit against Pierre Fabre USA Inc. and Pierre Fabre Dermo-Cosmetique USA Inc. * Why: Vales claims the companies falsely advertise that their Avène skincare products are preservative-free. * Where: The Piere Fabre class action lawsuit was filed in California federal court. A new class action lawsuit claims Pierre Fabre USA falsely advertises that its Avène skincare products are preservative-free. Plaintiff Ivy-Karina Vales filed the class action complaint against Pierre Fabre USA and Pierre Fabre Dermo-Cosmetique USA on Dec. 8 in California federal court, alleging violations of state and federal consumer laws. According to the class action lawsuit, the companies falsely advertise their Avène skincare products as preservative-free despite containing a well-known preservative. Vales claims the companies mislead consumers into paying a premium for products they believe are preservative-free, causing financial harm to consumers who prefer such products. As a result, Vales says she and other consumers are entitled to compensation for the price premium they paid for the products. She also seeks injunctive relief to prevent Pierre Fabre from continuing to market the products as preservative-free. Avène skincare products contain citric acid, lawsuit claims. According to the class action lawsuit, Pierre Fabre's Avène skincare products are marketed as preservative-free, leading consumers to believe they are purchasing premium products. "Defendants falsely and deceptively advertise the products as 'preservative-free' and/or '0% preservative,'" Vales says. "However, contrary to the products' Challenged Representations, the products actually contain citric acid - a well-defined artificial preservative ingredient commonly used in cosmetic products." Vales claims Pierre Fabre's advertising exploits consumers' desire for preservative-free products, allowing the company to charge higher prices. She says she and other consumers relied on the company's advertising when purchasing the products, believing they were free of preservatives. If consumers had known the products contained preservatives, they would not have purchased them or would have paid less, she alleges. Recently, various lawsuits have targeted the use of citric acid in "all natural" or "preservative free" claims. Frito-Lay is facing class action allegations over the use of citric acid in its Poppables snack, while Big Heart Pet Brands is accused of falsely advertising its Milk-Bone Dipped dog biscuits for the same reason. What do you think of the allegations made in this Avène skincare class action lawsuit? Let us know in the comments. The plaintiff is represented by Valter Malkhasyan and Erik Pogosyan of Malk & Pogo Law Group LLP. The Avène Fabre class action lawsuit is Vales v. Pierre Fabre USA Inc., et al., Case No. 5:25-cv-10523, in the U.S. District Court for the Northern District of California. Don't miss out! Read About More Class Action Lawsuits & Class Action Settlements:

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