PPriovant Therapeutics focuses on developing medicines for autoimmune diseases that carry the heaviest patient burden. It is in the clinical-stage phase, building a pipeline of therapies that specifically target the molecular problems driving severe autoimmune conditions. This approach aims to address patients who are underserved by current treatments. The company’s treatments work by focusing on the underlying molecular dysregulations to reduce disease activity and improve outcomes, rather than broadly suppressing the immune system. Priovant differentiates itself by prioritizing severe, underserved autoimmune diseases and pursuing targeted, mechanism-based therapies rather than one-size-fits-all drugs. The goal is to bring new, effective options to patients who lack good treatment choices and to move promising therapies through clinical development toward patient access.
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Industries
Company Size
51-200
Company Stage
N/A
Total Funding
N/A
Headquarters
New York City, United States
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The US Food and Drug Administration has approved Priovant Therapeutics' LISRAYA (brepocitinib) for treating adults with dermatomyositis, a rare autoimmune disease causing muscle weakness and skin lesions. The once-daily pill is the first targeted therapy approved for this condition. LISRAYA's approval follows the Phase 3 VALOR trial, the largest dermatomyositis study conducted. In the 52-week trial, 55% of LISRAYA patients achieved moderate improvement and minimal steroid use, compared to 30% on placebo. Among patients taking corticosteroids at baseline, 62% tapered to minimal or no steroid use versus 38% on placebo. The drug is now available in the US, with eligible patients potentially paying nothing per month through the LISRAYA My Compass Support programme. The FDA previously granted Priority Review and Orphan Drug Designation for the treatment.
US-based biotech company Priovant Therapeutics is dedicated to developing novel therapies for autoimmune diseases with high morbidity and few available treatment options.
As such, the trial failed to meet its primary objective, as assessed using the SLE Responder Index (SRI-4), a composite measure of disease activity, according to Roivant and Priovant Therapeutics, which are developing brepocitinib for other autoimmune disorders as well.
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We're working on gathering enough insights on this company, check back soon!
Industries
Company Size
51-200
Company Stage
N/A
Total Funding
N/A
Headquarters
New York City, United States
Founded
N/A
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Don't see your dream role? Check out thousands of other roles on Simplify.Browse all jobs