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Promega develops and supplies life-science tools, reagents, and instrumentation used by researchers to study biology, diagnose diseases, and ensure safety in food and water. Its products range from cloning vectors for gene manipulation to bioluminescent assays that measure biological processes, enabling scientists to monitor samples and obtain data. The company collaborates with scientists and institutions worldwide to evolve technologies and apply science to real-world problems, often co-developing solutions with partners. Promega differentiates itself through its strong emphasis on collaboration, a global network of 16 branches, and a commitment to sustainable business practices that support employees, communities, and customers. Its goal is to enable discovery and practical applications of biology by providing reliable, broadly available tools and services that advance science while protecting the environment and fostering community growth.
Industries
Biotechnology
Healthcare
Company Size
1,001-5,000
Company Stage
N/A
Total Funding
N/A
Headquarters
Madison, Wisconsin
Founded
1978
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Promega Corporation has authorised the RNA & Formulation Core at the University of British Columbia to manufacture and distribute mRNA constructs containing NanoLuc luciferase sequences. The agreement enables researchers working with mRNA and lipid nanoparticles to measure mRNA delivery and expression more effectively. NanoLuc is a small, highly stable bioluminescent reporter engineered by Promega that produces signals over 150 times brighter than conventional luciferase systems. When delivered and translated inside cells, it indicates whether mRNA reached its target and was successfully expressed—crucial for optimising therapeutic mRNA delivery systems. The UBC facility can now supply professionally produced, quality-controlled NanoLuc-encoding mRNA for research use, eliminating previous licensing and in-house production requirements. Applications include LNP delivery optimisation, mRNA vaccine development and gene therapy research.
Promega Corporation has announced a distribution agreement with NimaGen to expand access to the latter's IDseek massively parallel sequencing library prep kits for forensic laboratories. The partnership enables labs to access NimaGen's RC-PCR technology through Promega's established global network. NimaGen's IDseek portfolio includes over 20 products supporting applications such as autosomal STR profiling, Y-chromosomal analysis, microhaplotype analysis and mitochondrial DNA sequencing. The technology enables single closed-tube reactions designed for degraded and low-quantity forensic samples. The agreement allows forensic laboratories already using Promega's sample preparation and capillary electrophoresis tools to transition to massively parallel sequencing workflows whilst maintaining their existing supplier relationships. Promega has supported forensic laboratories for over 30 years across human identification workflows.
Promega Corporation has launched the TarSeer BRETSA Target Engagement System, a live-cell platform for detecting ligand-protein interactions using bioluminescence resonance energy transfer. The technology measures compound binding to target proteins in cells through changes in thermal stability, even for proteins lacking known chemical probes. The platform has been applied to more than 20 target classes and supports 96- and 384-well formats. It aims to bridge the gap between biochemical and cellular assays for difficult-to-study proteins, helping researchers validate weak chemical compounds and expand accessible targets in drug discovery workflows. Promega will debut the technology at the SLAS International Conference in Boston on 7–11 February 2026. The system complements Promega's existing NanoBRET Target Engagement System by addressing targets unsuitable for NanoBRET analysis.
China's National Medical Products Administration has approved Promega's OncoMate Microsatellite Instability Detection Kit as a companion diagnostic for Merck's KEYTRUDA cancer therapy. This marks Promega's first companion diagnostic to receive NMPA approval. The PCR-based assay identifies MSI-High solid tumour patients who may benefit from pembrolizumab treatment. The approval addresses a critical need in China, which faces one of the world's highest cancer burdens, with most advanced solid tumour patients eventually progressing after first-line therapy. The approval resulted from collaboration with Merck and reflects shared commitment to improving diagnostic access. Promega's MSI technology has also received regulatory approvals in the EU and US. The kit will soon be available for purchase in China.
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Industries
Biotechnology
Healthcare
Company Size
1,001-5,000
Company Stage
N/A
Total Funding
N/A
Headquarters
Madison, Wisconsin
Founded
1978
Find jobs on Simplify and start your career today