Proprio

Proprio

AI-powered surgical navigation with AR

Overview

Proprio makes the Paradigm platform, a surgical navigation system that uses light field technology, AI, and augmented reality to show real-time 3D views of a patient’s anatomy without radiation. It combines preoperative images with data from intraoperative sensors to create Volumetric Intelligence, helping surgeons see around obstacles and align instruments with the surgical plan. The system is mainly used in spine procedures such as lumbar fusions and scoliosis correction, and it passively collects data during surgery to build a rich data resource. Its goal is to improve surgical accuracy and efficiency while shifting the medical device industry toward data-driven, digital surgery, backed by FDA clearance for Paradigm.

About Proprio

Simplify's Rating
Why Proprio is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

VR & AR

Enterprise Software

AI & Machine Learning

Healthcare

Company Size

1,001-5,000

Company Stage

Series B

Total Funding

$78M

Headquarters

Seattle, Washington

Founded

2016

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Simplify's Take

What believers are saying

  • Third FDA clearance enables real-time 3D measurements in 2026.
  • Partnerships with Harms Study Group and Biedermann advance spine research.
  • LifeHealthcare expands distribution to Australia, New Zealand, Southeast Asia.

What critics are saying

  • Medtronic Mazor X erodes market share in 12-24 months.
  • Intuitive da Vinci 5 locks out robotic-dependent ORs in 18-36 months.
  • Synsurgical undercuts with 30% cheaper AR in Southeast Asia by 2027.

What makes Proprio unique

  • Paradigm uses light field technology for radiation-free 3D visualization.
  • Volumetric Intelligence fuses preoperative images with intraoperative sensors.
  • Replaces microscopes, navigation, loupes via AI and AR integration.

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Funding

Total Funding

$78M

Above

Industry Average

Funded Over

4 Rounds

Series B funding is typically for startups that have proven their business model and need more funding to expand rapidly—often by entering new markets or adding more products. Investors are usually venture capital firms that specialize in later-stage investments.
Series B Funding Comparison
Above Average

Industry standards

$35M
$43M
Proprio
$45M
Linktree
$65M
Substack
$100M
ClickUp

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Unlimited Paid Time Off

Paid Sick Leave

Paid Holidays

Parental Leave

401(k) Retirement Plan

401(k) Company Match

Mental Health Support

Commuter Benefits

Wellness Program

Phone/Internet Stipend

Company News

PR Newswire
Nov 12th, 2025
Proprio and Harms Study Group Partner to Advance AI-Powered Research in Spine Surgery

Proprio and Harms Study Group partner to advance ai-powered research in spine surgery. News provided by. By integrating intraoperative data from Proprio's Paradigm(TM) platform with the Harms Study Group registry, the partnership ushers in a new era of quantitative, AI-enabled spine surgery research SEATTLE, Nov. 12, 2025 /PRNewswire/ - Proprio, the surgical technology company pioneering AI-powered surgical intelligence, today announced a partnership with the Harms Study Group (HSG), a global network of distinguished surgeons dedicated to improving outcomes for children with spinal deformities. The new Proprio - HSG Research Collaborative will link real-time intraoperative data from Proprio's Paradigm(TM) platform with HSG's global outcomes registry, creating a powerful new foundation for research and data quality in spine deformity care. By capturing objective intraoperative measurements during live surgery and connecting them to long-term outcomes data, the collaboration aims to improve the precision, completeness, and consistency of registry data across HSG's international network of hospitals. The integrated dataset will support new research into surgical optimization, outcomes prediction, and the economics of data-led care. "For more than 30 years, the Harms Study Group has set the global standard for collaborative spine research," said Gabriel Jones, CEO of Proprio. "Their registry is one of the most important data assets in medicine. With the power of AI and computer vision, Paradigm can now build on those decades of learning, turning insight into a continuously learning system that measures, learns, and improves with every surgery." The collaboration will be built on a registry integration using Proprio's API, automating intraoperative data collection while reducing manual documentation. Proprio and HSG investigators will also co-author multicenter research studies and publications, expanding the evidence base for AI-driven surgical intelligence. "This technology allows us and the physicians we work with to objectively quantify what happens inside the operating room, something we've never had access to before," said Dr. Firoz Miyanji, Orthopedic Spine Surgeon at BC Children's Hospital and VP of Research for the Harms Study Group. "Working with innovative, mission-aligned companies in this new age of AI opens the door to entirely new research questions and, ultimately, better outcomes for our patients." "Our mission at HSG is to accelerate discovery and elevate standards in spine deformity care," added Michelle Marks, Executive / Research Director of the Harms Study Group. "Integrating Paradigm's intraoperative data directly improves the quality of the registry and the insights it can generate." For more information, visit www.propriovision.com. About Proprio Proprio is a Seattle-based surgical technology company pioneering the future of surgery through real-time data collection and AI-powered surgical intelligence. Its Paradigm(TM) platform combines proprietary computer vision, light-field imaging, and artificial intelligence to provide continuous 3D visualization, precise intraoperative measurement, and automated data capture, reducing radiation, improving efficiency, and unlocking new insight for surgeons and researchers worldwide. About the Harms Study Group (HSG) The Harms Study Group (HSG) is a worldwide cohort of surgeons committed to advancing pediatric and adolescent spinal deformity treatment through rigorous research and collaborative data-sharing efforts. Supported by the Setting Scoliosis Straight Foundation, HSG has spent decades shaping evidence-based care and improving patient outcomes across leading hospitals and research centers around the globe. SOURCE Proprio

GeekWire
Apr 8th, 2025
Proprio Receives Second Fda Clearance For Ai Platform That Captures Key Data During Surgery

GeekWire’s startup coverage documents the Pacific Northwest entrepreneurial scene. Sign up for our weekly startup newsletter , and check out the GeekWire funding tracker and venture capital directory .(Proprio Photo)Proprio, a Seattle startup using artificial intelligence for improved surgical precision, received its second major clearance from the U.S. Food and Drug Administration to include measurements taken during operations, the company announced Tuesday.The company’s technology platform, called Paradigm, captures high-definition images of the operating field from above and fuses them with images of pre-operative 3D scans. The system relies on advances in light field imaging, computer vision, machine learning, robotics and augmented reality.Surgeons can assess progress against their pre-operative plans in real time during surgery, and make data-informed decisions during a procedure, reducing the need for revision surgeries, and improving patient outcomes.“Evolving from highly educated guesswork to data-driven certainty with intraoperative measurements is game-changing,” said Gabriel Jones, CEO and co-founder of Proprio, in a statement.The technology has been used in hundreds of surgical cases, including at leading healthcare institutions and spine centers such as UW Medicine and Duke Health.“We’ve been using navigation in spine surgery for a while, but what this technology allows us to do is precisely find the right angle without intraoperative radiation and navigate it,” said Dr. Rick Bransford, a UW Medicine orthopedic surgeon at Harborview Medical Center. “The system can kind of tell us the trajectory and guidance to place screws with zero radiation

The Robot Report
Feb 2nd, 2025
Proprio Ceo Charts The Future Of Surgical Robotics As A Surgeon Shortage Looms

Proprio’s visualization technology uses volumetric intelligence to create a 3D view of anatomy and the surgical space without using radiation. | Source: Proprio. A looming U.S. surgeon shortage—projected to reach up to 19,900 unfilled positions by 2036, per AAMC data—is set to collide with an aging population and frequently crumbling rural healthcare infrastructure. Rural communities face the sharpest edge of this predicament: 136 rural hospitals closed between 2010 and 2021, leaving 60% of non-metro counties lacking adequate surgical care in 2019. Proprio is among the companies addressing this shortage with robotics

HIT Consultant
Jan 17th, 2025
Proprio And Lifehealthcare Expand Ai Surgical Guidance In Southeast Asia

Proprio and LifeHealthcare Expand AI Surgical Guidance in Southeast Asia. by Syed Hamza Sohail 01/17/2025 Leave a Comment. What You Should Know:– Proprio, the global leader in AI-powered surgical technology, today announced a strategic partnership with LifeHealthcare, a subsidiary of EBOS Group Limited. Through this partnership, LifeHealthcare will serve as the distribution partner of Proprio Paradigm in Australia and New Zealand. –  Additional phases of the agreement will expand distribution of the AI surgical guidance system throughout Southeast Asia.Addressing Global Surgical Challenges with Proprio’s Paradigm PlatformThe demand for high-quality surgical care is escalating worldwide, driven by physician shortages—projected to reach 20,000 surgeons over the next decade—and an aging population. Proprio’s Paradigm platform provides a groundbreaking solution to these pressing issues, revolutionizing the field of surgery by transforming current procedures and paving the way for future advancements.Unlike traditional surgical navigation systems, which rely on static 2D imagery, Paradigm leverages AI guidance to offer real-time, data-powered insights that enhance precision and improve patient outcomes. It stands as the first system to create a comprehensive dataset, establishing a system of record for surgery

HIT Consultant
Nov 22nd, 2024
Ai In Healthcare: Balancing Automation With Human Expertise

Kabir Gulati, VP of Data Applications at ProprioAI holds immense promise in healthcare, from improving patient care and operational efficiency to early disease detection and personalized treatment plans. AI’s potential in a patient-centered environment hinges on understanding its capabilities, limitations, and the critical role of human oversight. While AI can greatly enhance human abilities, it is not infallible and cannot replace human expertise. Recognizing and preparing for AI’s predictable (and unpredictable) outputs, ensuring responsible oversight, and promoting transparency are important benchmarks for effectively integrating AI into healthcare.AI’s applications in healthcare are diverse, offering improvements in diagnostics, treatment planning, patient monitoring, and administrative efficiency. For example, AI-driven diagnostic tools analyze medical images to detect conditions like cancer and cardiovascular diseases, improving early detection and patient outcomes. Others, like Suki AI, integrate with a clinician’s EHR, generate notes, suggest codes, and perform dictation

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