
Work Here?
Radical Numerics builds AI systems for scientific discovery, focusing on life sciences with multimodal models trained on biological data to speed up research, including generative genomics and AI-designed genomes. It develops foundational architectures and numerical computing frameworks to model complex physical systems (climate, materials, robotics) as learnable world models; Evo and Evo 2 generate gene-editing tools and whole genomes, showing AI can design biology. It differs from competitors by prioritizing science-specific architectures over repurposed language models and pursuing autonomous AI research to design AI itself, while open-sourcing models like RND1-Base to foster community progress and highlighting concrete demonstrations like AI-designed CRISPR systems. Its goal is to enable AI that can autonomously design AI and to accelerate discovery across biology, chemistry, materials, climate, and robotics using real, learnable models of complex physical and biological systems.
Industries
Data & Analytics
AI & Machine Learning
Biotechnology
Healthcare
Company Size
11-50
Company Stage
Seed
Total Funding
$50M
Headquarters
San Francisco, California
Founded
2025
See people who can refer or advise you
Help us improve and share your feedback! Did you find this helpful?
Total Funding
$50M
Above
Industry Average
Funded Over
1 Rounds
Industry standards
Radical Numerics has raised $50 million to develop AI models that simulate biological systems across DNA, RNA, proteins and epigenetics. The company builds on earlier work including Evo 2, a genome language model trained on 9 trillion DNA base pairs that can predict genetic variation effects without task-specific fine-tuning. Co-founder Eric Nguyen claims the company's Omnii model matched two years of Alzheimer's wet-lab research in days. However, he warns the same technology could enable dangerous pathogen creation if misused. The startup is focusing on both biological design and biodefence applications. The approach aims to learn directly from biological data rather than curated datasets, potentially accelerating drug discovery and diagnostics whilst raising questions about safe deployment of increasingly capable AI systems.
Radical Numerics raises $50M seed. Radical Numerics raises $50M seed round led by Emergence Capital to advance its AI research lab and build general biological intelligence models. Updated June 15, 2026 Radical Numerics, a San Francisco-based AI research lab focused on building general biological intelligence, has announced its official launch with $50 million in seed funding. The company, which specializes in generative genomics, aims to advance biological design for human health while developing biodefenses to monitor and protect against biological threats. Investors. The round was led by Emergence Capital, with additional participation from Obvious Ventures, Triatomic Capital, Factory, and First Spark Ventures. Radical Numerics use of funds. The company plans to use the new capital to scale its next-generation models and to expand its team by hiring frontier AI research talent. About Radical Numerics. Founded in 2026 by Eric Nguyen, Michael Poli, Stefano Massaroli, and Armin Thomas, Radical Numerics is an AI research lab dedicated to creating general biological intelligence. The company builds multimodal models that learn directly from biological data, including DNA, RNA, and proteins, to facilitate cancer diagnostics, drug target identification, and biosecurity efforts. Funding details. Company: Radical Numerics Raised: $50M Round: Seed Funding Date: June 15, 2026 Lead Investor: Emergence Capital Additional Investors: Obvious Ventures, Triatomic Capital, Factory, First Spark Ventures Company Website: https://www.radicalnumerics.ai/ Software Category: Artificial Intelligence Source: https://www.businesswire.com/news/home/20260615558179/en/AI-Lab-Radical-Numerics-Launches-with-%2450M-Seed-Round-To-Build-General-Biological-Intelligence Updated June 15, 2026
Radical Numerics: $50M seed for general biological AI. 3h ago · 0:00 listen · Source: CRISPR Medicine News Summary. An AI research lab called Radical Numerics has launched with 50 million dollars in seed funding. The company aims to build general biological intelligence. This funding will help them advance biological design for human health and build biodefenses. Radical Numerics was founded by a team who created the field of generative genomics. Their previous AI model, Evo, was featured in major science publications and used to design novel CRISPR systems. It also helped generate the first complete AI-designed genome. The new funding will scale their next generation of models and expand their team. Radical Numerics is developing a new class of AI that learns directly from biological data, unifying all aspects of biology into a single intelligence. Their multimodal models could lead to advancements in cancer diagnostics, drug identification, and biosecurity. The company is also previewing Omnii, their next-generation genomic language model. Early results show Omnii can identify regulatory variants and detect AI-generated or AI-manipulated pathogens. This matters because it could lead to powerful new tools for understanding and controlling biological systems. This is an AI-generated audio summary. Always check the original source for complete reporting.
AI lab Radical Numerics closes $50M seed round to develop General Biological Intelligence. Last Updated: 15 June 2026 Co-founder of JustAINews Key Points * Radical Numerics launches with $50M in seed funding to build AI that can read, write, and reason across all of biology. * The round was led by Emergence Capital, with Obvious Ventures, Triatomic Capital, Factory, First Spark Ventures, and Patrick Collison participating. * The company's founders created Evo and Evo 2, the AI models behind the first complete genome designed by artificial intelligence. Credits: JustAINews.com Radical Numerics, an AI research lab, has launched with $50 million in seed funding and a specific technical goal: build a single AI system capable of reading, writing, and reasoning across the full range of biology, covering DNA, RNA, proteins, and more. The company was founded by the team behind Evo and Evo 2, the models credited with creating the field of generative genomics. Eric Nguyen, who holds a PhD in Bioengineering and AI from Stanford, serves as CEO. The market they are entering is growing fast. According to Grand View Research, the global AI in genomics market was valued at $1.26 billion in 2025 and is forecast to reach $18.82 billion by 2033, at a compound annual growth rate of 40.3% between 2026 and 2033. Demand is coming from drug discovery, cancer diagnostics, and the broader push to analyze biological data at scale. Most existing AI tools in biology are built for one task at a time. They cannot reason across different types of biological information in a single system, and that constraint is the opening Radical Numerics is trying to fill. The $50 million seed round was led by Emergence Capital, a San Francisco venture firm with early investments in Salesforce, Veeva Systems, and Zoom. Other participants include Obvious Ventures, Triatomic Capital, Factory, and First Spark Ventures. Patrick Collison, co-founder and CEO of Stripe, was among the pre-seed backers. What Radical Numerics Means by General Biological Intelligence Standard AI models in biology are trained to do one thing well. A model built to predict protein shapes cannot also analyze gene regulation or scan for disease-causing DNA variants. Each task requires its own separate tool. Radical Numerics is training its models on multiple types of biological data at the same time, across what researchers call molecular layers: DNA, RNA, proteins, and beyond. The company calls this a multimodal approach. In plain terms, one model handles many types of biological information at once, rather than handing off between specialized tools. That capability also brings serious risks. Major AI labs have warned that commercial AI models could soon lower the barriers to planning biological attacks, and that more specialized biological design tools could help bad actors produce harmful agents. Scientists and policymakers are actively debating how to regulate access to this kind of software. Radical Numerics says it holds a dual mandate: advance biological design for human health, and build the detection systems needed to protect against its misuse. It is partnering with a US national laboratory on pathogen detection and biosurveillance, using the same models that power its medical work. "Most labs bolt safety on at the end. Radical Numerics built it into the foundation," said Gordon Ritter, Founder and General Partner at Emergence Capital. "They've paired frontier-model capability with real biosecurity expertise to open a scientific field that didn't exist before. That combination is rare, and it's why we led this round." Gordon Ritter, Founder and General Partner at Emergence Capital How Radical Numerics Plans to Use the $50M The funding will go toward three priorities: scaling the next generation of models, growing the research team, and building the computing infrastructure required to train at this level. A data center is already under construction, equipped with NVIDIA Blackwell chips. Hiring is underway for AI researchers, systems engineers, and computational biologists from institutions including Stanford, MIT, and Google DeepMind. Alongside the funding announcement, the company is previewing Omnii, its next-generation genomic language model. Early tests show it can identify functional genetic variants linked to Alzheimer's disease without having been specifically trained on that condition. This is called zero-shot transfer: the model applies what it learned during training to a domain it was never directly shown. The same model is also being used to detect AI-generated or AI-modified pathogens, an early application of the company's biosecurity work. On the medical side, Radical Numerics is working with a cancer diagnostics company to apply Omnii to pancreatic and multi-cancer detection. The approach combines multiple molecular signals into one diagnostic, targeting cases that existing single-signal tools may miss. The Founders and the Science Behind the Company The four co-founders all came from Liquid AI and hold advanced degrees from Stanford. Eric Nguyen is CEO, with a PhD in Bioengineering and AI. Michael Poli, Chief AI Scientist, also holds a Stanford PhD. Stefano Massaroli, President, did a postdoctoral fellowship with Yoshua Bengio, one of the most influential researchers in modern deep learning. Armin Thomas, CTO, completed a postdoc at Stanford under Chris Ré. Before starting Radical Numerics, the team built Evo and Evo 2, the largest openly available AI models trained on biological DNA. Both models were featured on the covers of Science and Nature respectively, and Eric Nguyen presented the work at TED2025. External scientists using the open-source models later produced the first complete genome designed by AI, a bacteriophage, which is a virus that infects bacteria and poses no risk to humans. "Evo showed that AI can generate DNA and whole genomes, the next generation of models will go further with the ability to control function, and eventually, create entirely new forms of life," said Eric Nguyen, CEO of Radical Numerics. "Our multimodal models are already far more capable, and we understand the responsibility that comes with that. The same models that can help cure disease may also lower the barrier to designing harmful biology. These forces are inseparable. Biology will be the most consequential application of AI." Eric Nguyen, CEO of Radical Numerics Scientific advisors include Eric Horvitz, Chief Scientific Officer at Microsoft; Chris Ré at Stanford; George Church at Harvard; and Andrew Weber, former US Assistant Secretary of Defense for Nuclear, Chemical, and Biological Defense Programs. The Investors Behind the Round Emergence Capital, which led the round, is a San Francisco-based firm founded in 2003 with a focus on early-stage enterprise technology. The rest of the round included Obvious Ventures, Triatomic Capital, Factory, and First Spark Ventures, with Patrick Collison participating at the pre-seed stage. Funding details. * Company name: Radical Numerics * Funding round: seed * Date: June 2026 * Funding amount: $50 million * Lead investors: Emergence Capital Get the industry's biggest AI news straight to your inbox.
Radical Numerics, an AI startup teaching machines to read and write DNA, has emerged from stealth with a $50 million seed round led by Emergence Capital. Obvious Ventures, Triatomic Capital, Factory and First Spark Ventures participated, with Stripe CEO Patrick Collison backing at pre-seed. Founded by researchers who created the field of generative genomics, the company built Evo and Evo 2, the first AI models capable of generating DNA at scale. Last September, researchers using Evo produced the world's first fully AI-designed functional virus. Unlike competitors focusing on single molecules, Radical Numerics' multimodal model understands entire biological systems simultaneously. The company has secured two early partnerships in cancer detection and pathogen characterisation. However, it acknowledges dual-use risks, having brought on former US assistant defence secretary Andrew Weber as advisor.
Find jobs on Simplify and start your career today
Industries
Data & Analytics
AI & Machine Learning
Biotechnology
Healthcare
Company Size
11-50
Company Stage
Seed
Total Funding
$50M
Headquarters
San Francisco, California
Founded
2025
Find jobs on Simplify and start your career today