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Relay Therapeutics

Drug discovery platform targeting protein motion

Overview

Relay Therapeutics uses its Dynamo platform to discover drugs by exploring how proteins move, enabling them to target proteins previously considered undruggable. The platform blends experimental data with computational modeling to identify and optimize therapeutic candidates, with a focus on precision oncology and genetic diseases. Its approach combines motion biology, data-driven design, and active partnerships (such as a worldwide license and collaboration with Genentech) with an internal drug pipeline. The company aims to bring life-changing medicines to patients by advancing clinical trials and securing licensing collaborations to fund and validate its therapies.

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About Relay Therapeutics

Simplify's Rating
Why Relay Therapeutics is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & AnalyticsAI & Machine LearningBiotechnologyHealthcare

Company Size

201-500

Company Stage

IPO

Headquarters

Cambridge, MA

Founded

2016

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What believers are saying

  • November 2026 cash of $848.6 million funds operations into 2029.
  • ASH 2026 will show updated ReInspire vascular-anomaly data on December 14, 2026.
  • Pfizer agreed in April 2026 to supply atirmociclib and palbociclib for Phase 3 work.

What critics are saying

  • ReDiscover-2 enrollment finishes mid-2027, delaying any breast-cancer revenue until 2028.
  • Relay warned it needs substantial additional funding after 2029, exposing shareholders to dilution.
  • Hayes v. Borisy settlement forces governance reforms and legal fees, showing continued shareholder friction.

What makes Relay Therapeutics unique

  • Relay’s Dynamo platform still turns protein motion into allosteric drugs.
  • Zovegalisib is the first pan-mutant selective PI3Kα inhibitor in clinical development.
  • Shannon Campbell joined in November 2026, signaling commercial readiness ahead of launches.

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Funding

Total Funding

$2.1B

Above

Industry Average

Funded Over

10 Rounds

Notable Investors:
Post IPO Equity funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Equity Funding Comparison Coming Soon

Benefits

  • Medical, dental, vision
  • Life, disability, & FSA
  • 401k
  • Commuter benefits
  • Parental leave
  • Home office stipend
  • Tuition reimbursement
  • PTO

Stock Price

Growth & Insights and Company News

6 month growth

0%

1 year growth

-1%

2 year growth

-5%
Associated Press
Nov 4th, 2026
Relay Therapeutics posts $81.7M Q3 net loss, holds $849M cash and eyes mid-2027 breast cancer enrolment

Relay Therapeutics reported a third-quarter 2026 net loss of $81.7 million, or $0.37 per share, up from $74.1 million a year earlier. Research and development spending rose to $77.1 million from $68.3 million, driven by clinical trial costs and one-off charges from ending its One Kendall Square lease. The company held $848.6 million in cash and investments on September 30, down from $910.9 million in June. It expects that to fund operations into 2029. Its Phase 3 ReDiscover-2 trial of zovegalisib in second-line breast cancer should finish enrolment in mid-2027. Updated data on zovegalisib in vascular anomalies will be presented at the American Society of Hematology meeting on December 14, 2026. Relay also hired Shannon Campbell as head of commercial.

TMCnet
Sep 22nd, 2026
X-Chem Announces Phase 3 Milestone in Collaboration with Relay Therapeutics

X-Chem Announces Phase 3 Milestone in Collaboration with Relay Therapeutics TMCnet News [September 22, 2026] | / | X-Chem Announces Phase 3 Milestone in Collaboration with Relay Therapeutics WALTHAM, Mass., Sept. 22, 2026 (GLOBE NEWSWIRE) - X-Chem, a global leader in innovative drug discovery services, announced the achievement of a milestone following Relay Therapeutics' initiation of a Phase 3 clinical trial of a drug candidate developed from a compound identified through an X-Chem DNA-encoded chemical library (DEL) screen. Relay Therapeutics, a leader in cutting-edge approaches to drug discovery, licensed an inhibitor of the oncology target phosphoinositide 3- kinase alpha (Pl3Ka) that was discovered through an X-Chem DEL screen. The inhibitor demonstrated differentiated pharmacology, mutant selectivity, a novel allosteric binding site and served as a starting point for Relay's innovative development of zovegalisib (RLY-2608), currently in a clinical trial. The initiation of this Phase 3 trial represents a milestone under the companies' Research Collaboration and License Agreement. "The unique selectivity and binding site of RLY-2608 are a testament to thepower of the X-Chem DEL platform to discover unique chemical matter with differentiated pharmacology," said X-Chem CEO Karen Lackey. "We are thrilled that our discovery platforms helped provide a starting point for a potential new treatment for patients with breast cancer. Hats off to the Relay team for having the drive and vision to push this project forward." "X-Chem's excellence in DEL technology was apparent from the very beginning of this exciting project, and we are pleased to continue to advance the clinical development of zovegalisib in patients with PI3Ka-driven diseases," said Relay CEO Sanjiv Patel. About X-Chem X-Chem is redefining small-molecule drug discovery through a powerful combination of computational science, discovery chemistry and data-driven insight. As the pioneer and global leader in DNA-encoded chemical library (DEL) technology, X-Chem helps biopharma partners identify differentiated hits, accelerate lead progression and advance complex programs with greater confidence. Learn more at www.x-chemrx.com. Media Contact Alli Cooke [email protected] 616.258.5769 [ Back To TMCnet.com's Homepage] |

Ticker Report
Sep 6th, 2026
Jupiter Topco LLC Makes New Investment in Relay Therapeutics, Inc. $RLAY

Jupiter Topco LLC purchased a new stake in shares of Relay Therapeutics, Inc. (NASDAQ:RLAY – Free Report) during the 2nd quarter, Holdings Channel.com reports. The fund purchased 46,273 shares of the company’s stock, valued at approximately $866,000. A number of other hedge funds have also modified their holdings of RLAY. Sanctuary Advisors LLC raised its […]

Ticker Report
Sep 1st, 2026
The Manufacturers Life Insurance Company Makes New $4.93 Million Investment in Relay Therapeutics, Inc. $RLAY

The Manufacturers Life Insurance Company purchased a new position in Relay Therapeutics, Inc. (NASDAQ:RLAY – Free Report) in the 2nd quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission (SEC). The fund purchased 263,506 shares of the company’s stock, valued at approximately $4,930,000. A number of other […]

MarketBeat
Aug 8th, 2026
Relay Therapeutics (NASDAQ:RLAY) posts quarterly earnings results, misses estimates by $0.02 EPS.

Relay Therapeutics (NASDAQ:RLAY) posts quarterly earnings results, misses estimates by $0.02 EPS. August 8, 2026 Key points. * Relay Therapeutics reported a quarterly loss of $0.41 per share, missing analysts' estimate by $0.02, while revenue of $0.35 million fell short of the $0.96 million consensus. * Shares rose to $19.77, near the company's 52-week high of $20.79. Analysts maintain a "Moderate Buy" consensus, with an average price target of $25.17. * Institutional investors own approximately 96.98% of the stock, while company insiders sold 427,356 shares worth about $7.46 million over the past quarter. * Five stocks to consider instead of Relay Therapeutics. Relay Therapeutics (NASDAQ:RLAY - Get Free Report) posted its quarterly earnings results on Thursday. The company reported ($0.41) EPS for the quarter, missing analysts' consensus estimates of ($0.39) by ($0.02), FiscalAI reports. The company had revenue of $0.35 million for the quarter, compared to the consensus estimate of $0.96 million. Relay Therapeutics price performance. NASDAQ RLAY traded up $0.02 during mid-day trading on Friday, reaching $19.77. The stock had a trading volume of 2,315,168 shares, compared to its average volume of 2,222,666. Relay Therapeutics has a 1 year low of $3.03 and a 1 year high of $20.79. The stock has a market cap of $3.79 billion, a PE ratio of -12.59 and a beta of 1.69. The company has a fifty day moving average price of $17.71 and a 200 day moving average price of $13.48. Insiders place their bets. In other Relay Therapeutics news, CEO Sanjiv Patel sold 48,199 shares of the stock in a transaction on Tuesday, July 7th. The stock was sold at an average price of $19.58, for a total transaction of $943,736.42. Following the sale, the chief executive officer directly owned 615,898 shares in the company, valued at approximately $12,059,282.84. This trade represents a 7.26% decrease in their position. The sale was disclosed in a document filed with the SEC, which is accessible through this hyperlink. Also, CFO Thomas Catinazzo sold 1,459 shares of the business's stock in a transaction on Tuesday, July 28th. The stock was sold at an average price of $18.61, for a total value of $27,151.99. Following the completion of the transaction, the chief financial officer owned 158,285 shares of the company's stock, valued at $2,945,683.85. This represents a 0.91% decrease in their position. The SEC filing for this sale provides additional information. The sale was made to cover tax withholding obligations related to the vesting of equity awards. In the last quarter, insiders have sold 427,356 shares of company stock valued at $7,461,240. 5.04% of the stock is currently owned by company insiders. Institutional trading of Relay Therapeutics. Institutional investors have recently made changes to their positions in the stock. AQR Capital Management LLC raised its holdings in shares of Relay Therapeutics by 11.9% during the first quarter. AQR Capital Management LLC now owns 364,946 shares of the company's stock valued at $956,000 after purchasing an additional 38,812 shares during the last quarter. MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. boosted its holdings in Relay Therapeutics by 6.6% in the first quarter. MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. now owns 84,069 shares of the company's stock worth $221,000 after purchasing an additional 5,238 shares during the last quarter. Millennium Management LLC boosted its holdings in Relay Therapeutics by 14.6% in the first quarter. Millennium Management LLC now owns 2,942,875 shares of the company's stock worth $7,710,000 after purchasing an additional 374,491 shares during the last quarter. Dynamic Technology Lab Private Ltd bought a new stake in Relay Therapeutics in the 1st quarter worth approximately $53,000. Finally, Woodline Partners LP grew its position in Relay Therapeutics by 448.4% in the 1st quarter. Woodline Partners LP now owns 1,518,561 shares of the company's stock worth $3,979,000 after purchasing an additional 1,241,657 shares during the period. Hedge funds and other institutional investors own 96.98% of the company's stock. Analyst upgrades and downgrades. A number of equities analysts have issued reports on the stock. Barclays boosted their price objective on shares of Relay Therapeutics from $27.00 to $30.00 and gave the company an "overweight" rating in a research report on Friday. Wall Street Zen raised Relay Therapeutics from a "sell" rating to a "hold" rating in a research note on Saturday, June 6th. The Goldman Sachs Group boosted their price target on Relay Therapeutics from $22.00 to $31.00 and gave the company a "buy" rating in a report on Tuesday, July 21st. Wells Fargo & Company upped their price target on Relay Therapeutics from $17.00 to $21.00 and gave the company an "overweight" rating in a research report on Tuesday, April 28th. Finally, Canaccord Genuity Group started coverage on shares of Relay Therapeutics in a report on Thursday, July 16th. They issued a "buy" rating and a $29.00 price target on the stock. Two equities research analysts have rated the stock with a Strong Buy rating, ten have issued a Buy rating and two have assigned a Sell rating to the stock. According to MarketBeat, the company has a consensus rating of "Moderate Buy" and an average target price of $25.17. Discover more American Consumer News MarketBeat Portfolio Tools Stock Profit Calculator About Relay Therapeutics. Relay Therapeutics, Inc is a clinical-stage biotechnology company focused on the discovery and development of precision therapies for oncology. Headquartered in Cambridge, Massachusetts, the company was founded in 2016 with the goal of targeting dynamic protein motion using an integrated scientific platform. Relay Therapeutics leverages computational modeling, structural biology, and experimental validation to identify small-molecule drug candidates that modulate the behavior of disease-associated proteins. The company's core business activity centers on its proprietary drug-discovery engine, which combines high-performance computing - including molecular dynamics simulations - with advanced experimental techniques such as cryo-electron microscopy and biophysical screening. This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest reporting and unbiased coverage. Please send any questions or comments about this story to [email protected]. Continue following MarketBeat Before you consider Relay Therapeutics, you'll want to hear this. MarketBeat keeps track of Wall Street's top-rated and best performing research analysts and the stocks they recommend to their clients on a daily basis. MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on... and Relay Therapeutics wasn't on the list. While Relay Therapeutics currently has a Moderate Buy rating among analysts, top-rated analysts believe these five stocks are better buys. The AI boom is creating opportunities across semiconductors, cloud computing, enterprise software, infrastructure, cybersecurity, and automation. Inside this report, you'll find 10 companies positioned to benefit as artificial intelligence moves from hype to real-world deployment and becomes a core growth driver for corporate America.

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