Remix Therapeutics

Remix Therapeutics

Develops mRNA-based treatments for rare diseases

About Remix Therapeutics

Simplify's Rating
Why Remix Therapeutics is rated
A-
Rated B on Competitive Edge
Rated A on Growth Potential
Rated A on Rating Differentiation

Industries

Biotechnology

Healthcare

Company Size

51-200

Company Stage

Growth Equity (Venture Capital)

Total Funding

$224.7M

Headquarters

Cambridge, Massachusetts

Founded

2018

Overview

Remix Therapeutics focuses on creating treatments for rare and difficult diseases, particularly targeting rare cancers and genetic disorders. Their main product, REM 422, is an oral small molecule that works by degrading messenger RNA (mRNA), which can stop the production of harmful proteins linked to these diseases. Currently, REM 422 is undergoing Phase 1 clinical trials for Adenoid Cystic Carcinoma and Acute Myeloid Leukemia, and it has received Orphan Drug Designation from the FDA, which offers benefits for drugs treating rare conditions. Unlike many competitors, Remix Therapeutics emphasizes a strong research and development approach, heavily investing in scientific research and forming partnerships with larger pharmaceutical companies. The company's goal is to provide new hope and effective treatments for patients suffering from serious illnesses, driven by the personal experiences of its founders and team.

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Simplify's Take

What believers are saying

  • Partnership with Roche could yield up to $1 billion in milestone payments.
  • FDA's Orphan Drug Designation for REM 422 offers market exclusivity and tax benefits.
  • Maria Koehler's appointment strengthens Remix's oncology drug development expertise.

What critics are saying

  • Competition from established mRNA therapy companies like Moderna and BioNTech.
  • Potential clinical trial failures could delay product development and approval.
  • Regulatory delays by the FDA could impact drug approval timelines.

What makes Remix Therapeutics unique

  • Remix's REMaster platform uniquely targets RNA processing to modulate gene expression.
  • REM 422 is a first-in-class mRNA degrader with Orphan Drug Designation.
  • The company focuses on rare diseases with significant unmet medical needs.

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Funding

Total Funding

$224.7M

Above

Industry Average

Funded Over

5 Rounds

Growth Equity VC funding comparison data is currently unavailable. We're working to provide this information soon!
Growth Equity VC Funding Comparison
Coming Soon

Growth & Insights and Company News

Headcount

6 month growth

-2%

1 year growth

-1%

2 year growth

-2%
GlobeNewswire
Mar 31st, 2025
Remix Therapeutics To Present At Stifel 2025 Virtual Targeted Oncology Forum

WATERTOWN, Mass., March 31, 2025 (GLOBE NEWSWIRE) -- Remix Therapeutics (Remix), a clinical-stage biotechnology company developing small molecule therapies to modulate RNA processing and address the underlying drivers of disease, today announced that Peter Smith, Ph.D., Co-Founder and Chief Executive Officer of Remix, will present a corporate overview at the Stifel 2025 Virtual Targeted Oncology Forum on Tuesday, April 8, 2025, at 1:00 p.m. ET.For investors interested in scheduling a one-on-one meeting with the Remix management team, please contact your Stifel representative.About Remix TherapeuticsRemix Therapeutics is a clinical-stage biotechnology company developing novel small molecule therapies designed to reprogram RNA processing and treat disease. The REMaster™ technology platform facilitates RNA processing pattern identification, leveraging these learnings to modulate gene expression. Remix’s innovative therapeutic approach has the potential to alter the way genes are read from the genome, to correct, enhance, or eliminate the gene message, thereby addressing disease drivers at their origin. For more information visit www.remixtx.com.Contacts:Media Contact:Lisa BuffingtonBuffington Commslbuffington@remixtx.comInvestor Contact:Will O'ConnorPrecision AQWill.OConnor@precisionaq.com

Marketing Interactive
Mar 4th, 2025
REV Media Group and Remix reshape affiliate marketing in MY with new solution

REV Media Group has teamed up with Remix to launch REV Affiliate+, an end-to-end affiliate marketing solution designed to help brands increase customer reach and sales through affiliate marketing in Malaysia.

PYMNTS
Dec 3rd, 2024
ThredUp Sells European Business Remix to Focus on US

ThredUp acquired Remix in July 2021, a $28.5 million deal designed to give it a foothold in the then-emerging European resale market, while providing the Bulgaria-based Remix with the resources to scale faster than it would on its own.

PR Newswire
Nov 26th, 2024
Remix Therapeutics To Present At 7Th Annual Evercore Healthconx Conference

CAMBRIDGE, Mass., Nov. 26, 2024 /PRNewswire/ -- Remix Therapeutics (Remix), a clinical-stage biotechnology company developing small molecule therapies to modulate RNA processing and address the underlying drivers of disease, today announced that Peter Smith, Ph.D., Co-Founder and Chief Executive Officer of Remix, will present a corporate overview at the 7th Annual Evercore HealthCONx Conference in Miami on Tuesday, December 3, 2024, at 3:25 p.m. ET. For investors interested in scheduling a one-on-one meeting with the Remix management team, please contact your Evercore representative. About Remix TherapeuticsRemix Therapeutics is a clinical-stage biotechnology company developing novel small molecule therapies designed to reprogram RNA processing and treat disease. The REMaster™ technology platform facilitates RNA processing pattern identification, leveraging these learnings to modulate gene expression

PR Newswire
Nov 20th, 2024
Remix Therapeutics To Present Preclinical Data Demonstrating Anti-Leukemic Activity Of Rem-422 In Aml At The 66Th American Society Of Hematology Annual Meeting And Exposition (Ash)

REM-422, a First-in-Class Small Molecule MYB mRNA Degrader, Demonstrates Anti-Leukemic Activity as Monotherapy and in Combination in Preclinical Models of AML. WATERTOWN, Mass., Nov. 20, 2024 /PRNewswire/ -- Remix Therapeutics (Remix), a clinical-stage biotechnology company developing small molecule therapies to modulate RNA processing and address the underlying drivers of disease, today announced an upcoming oral presentation at the 66th ASH Annual Meeting taking place from December 7-10, 2024, in San Diego, CA. Results demonstrate oral dosing of REM-422, a selective mRNA degrader of the MYB oncogene, leads to robust anti-leukemic activity observed both as a monotherapy and in combination across a genetically diverse set of preclinical models of acute myeloid leukemia (AML), including eradication of AML blasts in engrafted patient-derived xenograft (PDX) models of AML. The presentation also highlights the differentiated mechanism of action of REM-422 as it can be combined effectively with other agents used in the treatment of AML/MDS and retains activity in cell models engineered with mutations known to confer resistance to other targeted agents. "The preclinical data for REM-422 provide strong therapeutic rationale for our ongoing Phase I study in AML and High-Risk MDS," said Peter Smith, Ph.D., President and Chief Executive Officer of Remix Therapeutics

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