Skye Bioscience

Skye Bioscience

Develops cannabinoid-based drugs for glaucoma

Overview

Skye Bioscience is a biopharmaceutical company that develops proprietary cannabinoid derivatives to treat glaucoma and other diseases with significant unmet medical needs. Its work centers on turning cannabinoids into safer, more effective pharmaceutical agents that can be used in patients who lack good treatments. The company advances its products through research and development, clinical trials, and partnerships with healthcare providers and pharmaceutical firms to bring therapies to market in domestic and international markets. Compared to competitors, Skye Bioscience focuses on its own proprietary cannabinoid technologies and drug candidates, pursuing rigorous development and collaboration to address gaps where current treatments fall short. The overarching goal is to bring novel cannabinoid-based medicines to patients in need, expanding access to effective therapies through clinical evidence and strategic partnerships.

Funded Recently

About Skye Bioscience

Simplify's Rating
Why Skye Bioscience is rated
C
Rated C on Competitive Edge
Rated B on Growth Potential
Rated D+ on Differentiation

Industries

Biotechnology

Healthcare

Company Size

11-50

Company Stage

IPO

Headquarters

San Diego, California

Founded

2012

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Simplify's Take

What believers are saying

  • May 2026 nimacimab dosing cleared Cohort 2 after favorable safety in Cohort 1.
  • February 2026 data showed 22.3% weight loss at 52 weeks with semaglutide.
  • August 14 2026 financing package brought about $125 million and runway into 2029.

What critics are saying

  • Nimacimab still lacks Phase 2b data; Q4 2026 results can break the story.
  • Skye’s $22 million ELOC and financings signal heavy dilution before any commercialization.
  • Legacy Skye holders receive 5.38% of Fibrx; a failed merger leaves a tiny biotech shell.

What makes Skye Bioscience unique

  • Nimacimab is a peripherally restricted CB1 antibody, avoiding central nervous system exposure.
  • Skye’s obesity thesis combines CB1 antagonism with GLP-1s, targeting semaglutide plateau patients.
  • August 2026 Redx merger pivots Skye toward fibrosis assets under Fibrx Therapeutics.

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Funding

Total Funding

$263.8M

Above

Industry Average

Funded Over

14 Rounds

Post IPO Equity funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Equity Funding Comparison
Coming Soon

Benefits

Health Insurance

Remote Work Options

Stock Price

Company News

Minichart
Aug 24th, 2026
Skye Bioscience secures up to $22M equity line with Redmile for Redx acquisition

Skye Bioscience has secured an equity line of credit of up to $22 million with Redmile Group affiliate Redmile Biopharma Investments III. The agreement, disclosed on 24 August 2026, forms part of the financing package for Skye's previously announced acquisition of Redx Pharma Limited. Under the terms, Skye must direct monthly purchases capped at $2 million. The purchase price per share will be the lesser of the PIPE price or market price, with a maximum 10% discount to the PIPE price. Skye will also issue Redmile a warrant to purchase shares valued at $5 million, exercisable from January 2027 through January 2030. The ELOC facility runs for three years from the PIPE closing date. The ELOC size may be reduced if funded PIPE proceeds exceed $103 million, and will be terminated entirely if they reach $125 million.

Insider Media
Aug 14th, 2026
Redx Pharma to be acquired by Nasdaq-listed firm - combined group will be backed by $125m of new finance.

Redx Pharma to be acquired by Nasdaq-listed firm - combined group will be backed by $125m of new finance. 14 Aug 2026, 15:46 Cheshire-based biotechnology company Redx Pharma is set to be acquired by a Nasdaq-listed group, with a syndicate of new and existing healthcare institutional investors committing approximately about $125m of funds for the combined business. Skye Bioscience has entered into a definitive transaction agreement to acquire Redx, which is headquartered in Alderley Park, Macclesfield and is focused on the discovery and development of novel, small molecule, highly targeted therapeutics for the treatment of cancer and fibrotic diseases. The combined company will be led by Redx's current management team and board of directors and plans to operate under the name Fibrx Therapeutics, trading on Nasdaq. In connection with the transaction, a number of financing deals are in place which together will provide the combined company with aggregate gross proceeds of approximately $125m. Skye is entering into a securities purchase agreement with a syndicate of new and existing healthcare investors including Abingworth, British Business Bank, NEXTBio Capital and 5AM Ventures, as well as Redx's existing major shareholder, Redmile, for a private placement financing of approximately $68m. Additionally, Redx has entered into a subscription agreement for a Series A financing of $36m in gross proceeds, which was led by new Redx investor, Abingworth, and included British Business Bank and Redx's existing major shareholder, Redmile. Skye has further entered into an agreement with a fund affiliated with Redmile for a committed equity line facility of up to $22m. The combination has been approved by both boards of directors and is expected to complete in the fourth quarter of 2026.

FinanzNachrichten.de
Aug 14th, 2026
Skye Bioscience, Inc.: Skye Bioscience and Redx Pharma Announce Transaction Agreement and $125 Million in Financings

Combined company to trade on Nasdaq and operate as Fibrx Therapeutics, a fibrosis-focused company led by the Redx management team and boardCompany's lead program will be RXC008, Redx's GI-restricted

MarketScreener
Aug 14th, 2026
Skye Bioscience and Redx Pharma Announce Transaction Agreement and $125 Million in Financings

Combined company to trade on Nasdaq and operate as Fibrx Therapeutics, a fibrosis-focused company led by the Redx management team and boardCompany’s lead program will be RXC008, Redx’s...

Associated Press
May 12th, 2026
Skye Bioscience reports Q1 2026 results with $17.1M cash as CBeyond obesity study advances

Skye Bioscience has initiated its CBeyond Expansion Study evaluating nimacimab for obesity treatment, with Cohort 1 assessing 400mg IV weekly doses versus placebo. A Cohort Review Committee is scheduled to review safety data on 18 May 2026 to determine progression to Cohort 2, which will evaluate 600mg doses. The company reported first quarter 2026 results with cash and short-term investments of $17.1 million as of 31 March, expected to fund operations through Q4 2026. Net loss totalled $12.5 million for the quarter, compared to $11.1 million in the prior year period. Skye expects topline data from the expansion study in Q4 2026. Previously reported data showed nimacimab plus semaglutide achieved approximately 3% additional weight loss versus semaglutide alone at 26 weeks.

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