
Work Here?
Tahoe Therapeutics engineers AI-powered models of human cells to improve drug design, focusing on oncology and the RAS network. Its Mosaic platform generates in vivo, single-cell perturbation data by pooling cells from hundreds of diverse patient models into a single experiment, like a mosaic tumor in a mouse. The resulting Tahoe-100M dataset (100 million data points, 60,000 drug–cell interactions) trains AI models to identify novel drug targets and candidates. The company pursues internal drug development and strategic partnerships, including a 2026 joint venture with Alloy Therapeutics to advance antibody-drug conjugates and share larger datasets to accelerate discovery.
Industries
Data & Analytics
AI & Machine Learning
Biotechnology
Healthcare
Company Size
11-50
Company Stage
Series A
Total Funding
$42M
Headquarters
San Francisco, California
Founded
2022
See people who can refer or advise you
Help us improve and share your feedback! Did you find this helpful?
Total Funding
$42M
Above
Industry Average
Funded Over
2 Rounds
Industry standards
Unlimited Paid Time Off
Health Insurance
Vision Insurance
Dental Insurance
AWS announces 21 startups selected for the AWS generative AI accelerator. AWS Startups * Startup * Learn * AWS announces 21 startups selected for the AWS generative AI accelerator AWS announces 21 startups selected for the AWS generative AI accelerator by Kathryn Van Nuys | 11 July 2024. Page topics. Meet the inaugural Generative AI cohort. AWS is excited to announce the cohort of startups accepted into the global AWS Generative AI Accelerator. The program kicks off May 24th at our San Francisco AWS Startup Loft and closes on July 27th. Over the course of their 10-week program, participants will receive tailored technical advice, dedicated mentorship, an opportunity to pitch their demos to venture capitalists (VCs) in the AWS network, and up to $300,000 in AWS credits. Critically, they will also have the opportunity to foster lifelong connections with their fellow founders and within AWS. Our finalists come from various industries, backgrounds, and geographic regions, but all they have one thing in common: they are using generative artificial intelligence (AI) technology to drive unprecedented innovation in their space. They're exploring practical solutions to problems such as illiteracy and healthcare burnout and designing tools that drastically reduce time spent on costly, tedious tasks. No matter their vision, all of these startups are proving what's possible with generative AI and boldly reinventing applications, data touchpoints, and customer experiences, to name a few. Backing the upcoming leaders of the generative AI landscape. Startups are the lifeblood of innovation, and AWS is eager to support them in developing incredible generative AI solutions. Many of the AWS Startups team are former founders or VCs, and we embrace this chance to give back to these startups in meaningful, actionable ways. "Generative AI holds tremendous potential to revolutionize how humans interact with technology and with each other, while democratizing access to new and existing technology in a way that is unprecedented." says Jon Jones, vice president of compute and AI/ML services at AWS. "Customers are already seeing value in streamlining processes, accelerating product development, and using AI as a trusted companion to increase productivity and better serve their clients." We are excited to partner with these innovators on their journey to solve some of the world's biggest challenges." Drumroll, please. Please join us in extending a warm welcome to the 21 AWS Generative AI Accelerator program finalists Education. Ello Ello leverages large language models (LLM) and AI solutions to perfectly tailor literacy lessons to each young student they reach. Through interactive reading sessions from real books, Ello becomes a motivational learning companion that transforms children into curious, enthusiastic readers. Marketing, social, and advertising. Crate On a mission to create an open internet with no boundaries, Crate invites users to curate a personal, shareable artifact made up of their favorite pieces from anywhere on the web. The team puts AI in the hands of users to help them tell better stories with auto generated images, text, and instant summaries. qlip qlip is an AI-powered video highlights generator that helps users grow their social media presence by automatically repurposing long-form videos into short highlights primed for today's audiences. OpenAds OpenAds solves advertising challenges for publishers, consumers, and advertisers by identifying and suggesting ads that match a business' user experience UX, are tailored to customer advertising and privacy preferences, and keep creative control in the hands of advertisers. Entertainment and gaming. Leonardo Ai Leonardo Ai is an AI-driven content production suite tailored for creators across diverse sectors, with a core focus on game development artists. Through the platform, developers can utilize generative AI solutions that integrate with their workflows to unlock their creativity and accelerate content production from months to minutes. Storia Built by leading AI researchers and engineers, Storia operates as a creative assistant for rapid film previsualization and production. Story producers can experiment with AI-generated videos, visualize what their product would look like shot in different styles, and build collaborative and comprehensive storyboards in minutes. Krikey Krikey uses generative AI to make it easier for creators to breathe life into animations, helping them automate character motion with a variety of 3D avatars, augmented reality (AR) gaming toolkits, and 3D animations. Animations can be seamlessly integrated and exported into the creator's platform of choice, significantly shortening production time and enhancing the creative process. Poly Poly is an AI-enabled infinite design asset marketplace (offering seamless physically based rendering [PBR] textures, illustrations, icons, sounds, and many more) that lets anyone use or generate stunning, 8K high definition (HD) professional design assets in seconds with AI. Flawless To counteract the rising on-set production costs and time constraints, Flawless gives artists a suite of cinematic-quality AI-powered tools that allow them to rapidly and affordably iterate, experiment, and refine their content. Healthcare and life sciences. Knowtex Knowtex empowers clinicians with voice AI automated note-taking and coding from natural conversation to combat burnout and allow focus on patient care. Vevo Vevo is building the world's first atlas of how drugs interact with patient cells in living organisms at single cell resolution. Vevo's foundation models trained on this atlas faithfully capture disease biology, enabling generative design of drugs that are more likely to treat disease in humans. Ordaōs Ordaōs is a human-enabled, machine-driven drug design company. Their miniPRO proteins help drug hunters deliver treatments that are safer and more effective than traditional discovery methods. Nosis Bio Nosis Bio is enabling the future of targeted drug delivery by integrating deep expertise in generative AI and high-throughput biochemistry. Finance. Theia Insights Theia Insights leverages the power of AI to synthesize and distill financial data, generating real-time insights beyond human research capability, to inform the investment management community, helping individual and institutional investors make better decisions. Data and knowledge management. Unwrap Powered by AI and ML, Unwrap analyzes data from multiple customer feedback channels at scale, providing them with auto-labeling, semantic search, and automatic alerts that strengthen the feedback loop between companies and their customers. Stack AI Stack is a no-code interface that helps businesses of all sizes build and deploy AI applications including chatbots, document processing, content creation, and automated customer support in minutes. Nixtla Nixtla is building a state-of-the-art disruptive open-source ecosystem that uses AI to unlock scalable, lightning-fast, and user-friendly time series forecasting and anomaly detection. Wand Wand enables businesses to sync data from multiple sources to rapidly build collaborative, measurable, and scalable AI solutions. From predictive models to customized LLMs, teams have the power to solve business problems and create value faster than ever before. Griptape Griptape's open source framework and managed service enables developers to enhance LLMs with chain of thought capabilities, creating context-aware conversational, copilot, and autonomous agents. AI ethics, safety, and security. Bunked Bunked distinguishes AI-generated content from real content using blockchain technology. Protopia AI Protopia AI provides data protection and privacy-preserving AI/ML technologies that specialize in enabling AI algorithms and software platforms to operate without the need to access plain-text information. The company works with enterprises and generative AI/LLM providers to enable maintaining ownership and confidentiality of enterprise data while using AI/ML solutions. Kathryn Van Nuys. Kathryn Van Nuys is the Head of North America Startup Business Development at Amazon Web Services (AWS). Kathryn spent the earlier part of her career in financial services working in capital markets as well as sales and trading at Citigroup and Lehman Brothers. She later joined a number of early-stage startups, building their capital markets and partnership teams, before moving on to AWS to scale her efforts in helping startups to achieve growth.How was this content? More ways to grow on AWS. Did you find what you were looking for today? Let us know so we can improve the quality of the content on our pages
Tahoe Therapeutics selects Parse Biosciences' GigaLab to generate 300 million single cell profiles for large-scale perturbation atlas. Business Wire IndiaParse Biosciences, a leading provider of accessible and scalable single cell sequencing solutions, today announced that Tahoe Therapeutics has selected Parse's GigaLab to generate data for its upcoming 300M cell project. Tahoe will use its proprietary Mosaic technology to generate samples consisting of 300M cells from large arrays of disease models, genetically or chemically perturbed. Under this agreement, Parse will apply its Evercode(TM) chemistry and high-throughput automation to these samples to deliver the largest perturbation-focused single cell dataset ever produced. Parse's GigaLab, designed specifically for million- to hundred-million-cell projects, has rapidly become an industry benchmark for large-scale, reproducible single cell data generation. The facility integrates high-capacity liquid handling, standardized workflows, and end-to-end QC to enable dataset sizes previously unattainable for most research organizations. The Tahoe project represents one of the largest sequencing initiatives undertaken at GigaLab to date and underscores the increasing industrial demand for massive single cell atlases capable of training modern AI systems. "This collaboration demonstrates how scalable single cell technology can meet the demands of modern drug discovery," said Charlie Roco, PhD, Chief Technology Officer and Co-founder at Parse Biosciences. "By combining our GigaLab platform with Tahoe's perturbation engine, we are enabling a dataset that can power the next generation of AI models, changing how therapies are discovered." The 300-million-cell project expands Tahoe Therapeutics' lead in building foundational perturbation datasets that capture how drugs, targets, and disease contexts interact across diverse biological systems. These high-dimensional datasets are made uniquely possible by Tahoe's Mosaic platform and form the next-generation foundational datasets that power virtual cell models, enabling more accurate predictions of therapeutic response, mechanism of action, and patient variability. Today's drug discovery pipelines are constrained by datasets that lack drug discovery focused perturbations and biological diversity needed to train predictive AI systems. By contrast, Tahoe's foundational datasets will incorporate: These features allow Tahoe to identify unexpected drug/cell interactions, uncover new biology, and explore therapeutic avenues that traditional in vitro systems often miss. "Scaling single cell perturbation data is essential for building AI models that understand human biology," said Johnny Yu, CSO of Tahoe Therapeutics. "Leveraging Parse's GigaLab, we're able to perform single cell sequencing on samples generated from our Mosaic technology at unprecedented depth and diversity, moving us closer to scale of foundational datasets that power our virtual cell models, which can predict therapeutic outcomes across patients and diseases." With this agreement, Parse and Tahoe together highlight a new reality in the life sciences: the next generation of therapeutic discovery requires data at a scale that only a small number of expert entities, equipped with highly automated, industrial-grade platforms, can produce. By delivering sample preparation and sequencing for this dataset through its GigaLab, Parse continues to set the standard for what is technically feasible in large-scale single cell biology, while enabling innovators like Tahoe to build AI systems rooted in far richer biological context than was previously possible. About Tahoe Therapeutics Tahoe Therapeutics is building AI-powered models of the human cell to design better drugs for more patients. Its technology platform generates large-scale, perturbative single-cell datasets that enable a new generation of biological foundation models. Based in South San Francisco, Tahoe was founded by a team of scientists and technologists advancing the frontiers of drug discovery, genomics, and machine learning. Learn more at tahoebio.ai. About Parse Biosciences Parse Biosciences is a global life sciences company whose mission is to accelerate progress in human health and scientific research. Empowering researchers to perform single cell sequencing with unprecedented scale and ease, its pioneering approach has enabled groundbreaking discoveries in cancer treatment, tissue repair, stem cell therapy, kidney and liver disease, brain development, and the immune system. With technology developed at the University of Washington by co-founders Alex Rosenberg and Charles Roco, Parse has raised over $100 million in capital and is used by approximately 3,000 customers across the world. Its growing portfolio of products includes Evercode(TM) Whole Transcriptome, Evercode(TM) TCR, Evercode(TM) BCR, Gene Select, and a solution for data analysis, Trailmaker(TM). Parse Biosciences is based in Seattle's vibrant South Lake Union district, where it recently expanded into a new headquarters and state-of-the-art laboratory.
Tahoe Therapeutics raised USD 30M, with backers including Amplify Partners, Databricks Ventures, Mubadala Capital, and other major investors.
Tahoe Therapeutics has secured $30 million in funding to create the world's largest dataset for training AI models of human cells. The initiative aims to generate one billion single-cell datapoints and map one million drug-patient interactions, facilitating the discovery of new precision medicines for cancer and other diseases. Tahoe plans to partner with a single entity to share the data and expedite its application.
Vevo Therapeutics has officially released the Tahoe-100M, described as the world's largest single-cell dataset, in collaboration with the Arc Institute.
Find jobs on Simplify and start your career today
Industries
Data & Analytics
AI & Machine Learning
Biotechnology
Healthcare
Company Size
11-50
Company Stage
Series A
Total Funding
$42M
Headquarters
San Francisco, California
Founded
2022
Find jobs on Simplify and start your career today