Third Pole

Third Pole

Develops portable nitric oxide therapies

Overview

Third Pole Therapeutics develops medical devices and therapies for heart and lung conditions. Its flagship portable inhaled nitric oxide device delivers nitric oxide gas to improve blood flow and oxygen delivery, while eNOfit is a wearable platform that continuously and controllably administers nitric oxide. Revenue comes from selling devices to hospitals and through partnerships with other medical companies, and the company differentiates itself by combining portable NO delivery with a wearable drug-delivery platform and maintaining strict quality and regulatory standards (ISO 13485:2016). The goal is to improve patient outcomes and broaden treatment options in cardiopulmonary medicine by developing, manufacturing, and commercializing advanced nitric oxide therapies.

Significant Headcount Growth

About Third Pole

Simplify's Rating
Why Third Pole is rated
C
Rated B on Competitive Edge
Rated C on Growth Potential
Rated D+ on Differentiation

Industries

Industrial & Manufacturing

Healthcare

Company Size

11-50

Company Stage

Debt Financing

Total Funding

$106.4M

Headquarters

Waltham, Massachusetts

Founded

2014

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Simplify's Take

What believers are saying

  • March 2024 feasibility results validated safety and practicality in PH-ILD patients.
  • Patents published in 2025-2026 strengthen licensing leverage against imitators.
  • The MTEC page says eNOfit was ready for clinical trials in 2025.

What critics are saying

  • No FDA approval exists yet; commercialization still depends on larger randomized studies.
  • Third Pole relies on one category: inhaled nitric oxide, creating brutal platform concentration risk.
  • Without follow-on financing after 2024, trial expansion and launch timelines stall.

What makes Third Pole unique

  • Tankless eNOfit targets portable nitric oxide delivery, unlike bedside gas cylinders.
  • Third Pole owns a deep nitric oxide patent stack, including 2025-2026 filings.
  • FDA-granted IDE and 2024 feasibility completion de-risk the core platform.

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Funding

Total Funding

$106.4M

Above

Industry Average

Funded Over

7 Rounds

Debt funding comparison data is currently unavailable. We're working to provide this information soon!
Debt Funding Comparison
Coming Soon

Benefits

Wellness Program

Mental Health Support

Remote Work Options

Flexible Work Hours

Conference Attendance Budget

Professional Development Budget

Stock Options

401(k) Retirement Plan

401(k) Company Match

Health Insurance

Dental Insurance

Vision Insurance

Disability Insurance

Life Insurance

Paid Vacation

Paid Holidays

Paid Sick Leave

Parental Leave

Family Planning Benefits

Fertility Treatment Support

Adoption Assistance

Childcare Support

Elder Care Support

Professional Certification Support

Tuition Reimbursement

Training Programs

Mentorship Program

Gym Membership

Phone/Internet Stipend

Home Office Stipend

Growth & Insights and Company News

Headcount

6 month growth

3%

1 year growth

3%

2 year growth

-11%
Business Insider
May 27th, 2026
Micron Biomedical expands leadership to mobilize for pivotal studies and commercialization of first needle-free dissolvable vaccines and therapeutics.

Micron Biomedical expands leadership to mobilize for pivotal studies and commercialization of first needle-free dissolvable vaccines and therapeutics. May. 27, 2026, 08:00 AM ATLANTA, May 27, 2026 (GLOBE NEWSWIRE) - Micron Biomedical, a clinical-stage biotechnology company advancing needle-free vaccines and therapeutics, today announced the appointment of Elizabeth Holmberg as Chief Financial Officer as part of the company's efforts toward commercialization of its proprietary needle-free drug delivery platform and products. Earlier this month, the company celebrated the grand opening of its commercial-scale manufacturing site in Georgia. "Micron is at a pivotal juncture where strong clinical data, market demand and manufacturing infrastructure have set the foundation for us to bring our dissolvable microarray vaccine and therapeutic technology into pivotal studies, FDA approval and commercial availability so that we can make life-changing innovations accessible," said Steven Damon, Chief Executive Officer of Micron Biomedical. "With the appointment of Elizabeth Holmberg as Micron's Chief Financial Officer we are poised to build on her decades of strategic partnering and commercialization experience in lifesaving inhaled therapeutics to bring vaccines and therapeutics to patients without needles, without pain and without the complexities of manufacturing, storing, transporting and administering medications with needles and syringes." Holmberg joins Micron Biomedical with more than 30 years of financial leadership experience in biotechnology, medical device, and pharmaceutical companies, where she has consistently helped organizations secure capital, build scalable infrastructure, negotiate transformative strategic partnerships, and prepare for commercialization and public markets. Most recently, Holmberg served as Chief Financial Officer of Third Pole Therapeutics, where she built the company's finance and human resources functions and helped secure more than $100 million in financing including major pharmaceutical partnerships. She also negotiated a global commercialization and distribution agreement valued at more than $500 million, demonstrating her ability to structure partnerships that accelerate market entry and maximize value creation. Previously, Holmberg served as Chief Financial Officer of Ikaria, where she led their spin-out in 2008, securing $275 million in debt financing to support the company's growth and IPO readiness. Ikaria was subsequently acquired by Mallinckrodt in 2015 for $2.3B. Earlier in her career, she held a senior finance leadership role at INO Therapeutics (which became Ikaria) where she supported the successful commercial launch of INOmax(R)-a critical intervention for newborns suffering from Hypoxic Respiratory Failure. "Disrupting access to healthcare requires a new approach to manufacturing, storing, transporting and administering medicines and vaccines that are currently injected and I am honored to step into this role during such a critical juncture when we are poised to significantly accelerate the availability of Micron's products," said Holmberg. "I am committed to building on Micron's strong financial foundation to drive continued success as we expand our pipeline, scale up manufacturing and bring life-changing innovations to patients that immediately improve health outcomes, operational efficiencies and patient experiences." Micron Biomedical is advancing a proprietary dissolvable microarray technology designed to deliver vaccines and therapeutics painlessly through the skin without needles. The platform is designed to simplify administration, reduce or eliminate sharps waste, lessen cold chain requirements, and improve access to medicines worldwide. The company is preparing for pivotal clinical studies and commercial manufacturing scale-up as it works toward bringing its first products to market. About Micron Biomedical Micron Biomedical is the leader in dissolvable microarray-based, drug and vaccine administration technology with a growing pipeline of needle-free versions of previously injectable-only medicines. The company is a clinical-stage life science company on a rapid path to commercializing its proprietary dissolvable, microarray technology. Micron's technology is designed to improve access and achieve better health outcomes globally through injection-free, painless, and simple and/or self-administration of drugs and vaccines, and by eliminating or reducing the need for cold chain transport and storage, enhancing safety and efficacy, and improving patient compliance. Micron partners with and/or receives funding from private and public pharmaceutical and biotech companies, the Gates Foundation, the Centers for Disease Control and Prevention (CDC), PATH, the Coalition for Epidemic Preparedness Innovations (CEPI), Biomedical Advanced Research and Development Authority (BARDA) and the Georgia Research Alliance. For more information visit www.micronbiomedical.com Media Inquiries: Shira Derasmo Cuttlefish Communications +1 917 280 2497 [email protected] Markets Insider and Business Insider Editorial Teams were not involved in the creation of this post. Sponsored Financial Content Trade Faster, Trade SmarterTradeStation delivers powerful tools and a seamless experience for self-directed traders.TradeStation | Sponsored

Intelligence360 News
Apr 8th, 2024
Third Pole Has Filed A Notice Of An Exempt Offering Of Securities To Raise $10 Million In New Equity And Debt Financing.

Third Pole has filed a notice of an exempt offering of securities to raise $10 Million in New Equity and Debt Financing. Third Pole has filed a notice of an exempt offering of securities to raise $10 Million in New Equity and Debt Financing.According to filings with the U.S. Securities and Exchange Commission, Third Pole is raising up to $10,000,000.00 in new funding. Sources indicate that as part of senior management President, Basil Athenson played a key role in securing the recent investment and it will aid in aggressively expanding the company, as well as broaden and accelerate product development.About Third PoleThird Pole, Inc. is a US-based company developing next generation life-saving cardiopulmonary therapies. We are building on our teams legacy in inhaled nitric oxide (NO), the current standard of care, to develop next generation life-saving heart and lung therapies

Bionews, Inc.
Dec 13th, 2023
Early study of inhaled nitric oxide delivery system doses 1st patient

In 2017, Third Pole won a Johnson & Johnson Innovation award for the iNO-generating device.

BioSpace
Dec 15th, 2022
Third Pole Therapeutics Receives $32M Strategic Equity Investment to Accelerate its Tankless Inhaled Nitric Oxide (iNO) Platform | BioSpace

Third Pole Therapeutics, a privately held company developing critical life-sustaining cardio-pulmonary therapies, announced today a $32M equity investment, from a large medical device innovator.

Benzinga
Dec 14th, 2022
Third Pole Therapeutics Receives $32M Strategic Equity Investment To Accelerate Its Tankless Inhaled Nitric Oxide (Ino) Platform

Funding will support the final development phase prior to planned 2023 FDA submission of the company's "breakthrough" designated eNOcare™ hospital deviceWALTHAM, Mass., Dec. 14, 2022 (GLOBE NEWSWIRE) -- Third Pole Therapeutics, a privately held company developing critical life-sustaining cardio-pulmonary therapies, announced today a $32M equity investment, from a large medical device innovator.Bill Athenson, CEO of Third Pole, stated, "We are thrilled to receive this investment, which raises Third Pole Therapeutics' series B financing and commitments to date to over $85M. I am particularly pleased to welcome this strategic investor and partner given our closely aligned missions. This investment and partnership will accelerate the entry of eNOcare™, our advanced portable inhaled nitric oxide (iNO) device, into the iNO hospital market." Mr. Athenson continued, "This significant investment in Third Pole Therapeutics follows considerable diligence of our engineering and regulatory readiness and serves as a strong endorsement of our technology and team's ability to deliver critical care systems that exceed safety and performance requirements established by regulatory bodies and the most demanding care professionals. We are targeting a 2023 FDA submission for our eNOcare™ hospital system into the existing and underpenetrated $600 million iNO hospital market."Bill Heiden, Third Pole's Chairman added, "This strategic investment in Third Pole Therapeutics is directly aligned with both organization's mission to advance unique, disruptive, cost-effective solutions that improve outcomes in heart and lung-failure patients

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