X

Xyme

AI-designed enzymes catalyzing synthetic chemistry

Overview

Company Does Not Provide H-1B Sponsorship

Xyme designs AI-generated enzymes, called xymes, that catalyze chemical reactions and expand the toolkit of synthetic chemistry. It combines artificial intelligence, quantum chemistry, and experimental data to create enzymes tailored to drive specific reactions. The product is a designed enzyme, produced in the lab, validated through experiments, and guided by AI-driven predictions of structure and activity to enable catalysis across a wide range of chemical processes. Xyme differentiates itself by integrating AI, quantum chemistry, and real-world experimental validation to design enzymes capable of catalyzing many reactions, positioning two UK locations (Oxford and Manchester) as innovation hubs. The company aims to address large societal challenges by advancing synthetic chemistry, growing its team with AI and biotech experts, and building a scalable platform to design and deploy new enzymes for diverse industries.

Work here?Claim your company

About Xyme

Simplify's Rating
Why Xyme is rated
C+
Rated B on Competitive Edge
Rated B on Growth Potential
Rated D+ on Differentiation

Industries

Data & AnalyticsIndustrial & ManufacturingAI & Machine LearningBiotechnology

Company Size

11-50

Company Stage

N/A

Total Funding

N/A

Headquarters

Oxford, United Kingdom

Founded

2024

Get referred to Xyme

See people who can refer or advise you

Simplify Jobs

Simplify's take

What believers are saying

  • The June 19 2026 Emyx launch strengthens Xyme's AI enzyme design narrative.
  • Oxford and Manchester hiring through October 2026 shows active platform expansion.
  • Bank of America invited Hopkins on February 6 2026, validating industrial interest in Xyme.

What critics are saying

  • Xyme discloses no funding round, exposing a short runway against capitalized biotech rivals.
  • Hiring remains thin in Oxford and Manchester, signaling slow scale before 2027 commercialization.
  • One founder, Andrew Hopkins, concentrates strategy and reputation; a failed platform shift kills the company.

What makes Xyme unique

  • Andrew Hopkins launched Xyme in 2024 after Exscientia and AI drug discovery.
  • June 19 2026 Emyx claimed faster, cheaper protein generation than rival enzyme models.
  • March 14 2026 XYM-357 showed 92% activity hit rate and 78% expression in validation.

Help us improve and share your feedback! Did you find this helpful?

Benefits

  • Professional Development Budget
  • Conference Attendance Budget
  • Flexible Work Hours

Growth & Insights and Company News

6 month growth

2%

1 year growth

2%

2 year growth

19%
This Is Oxfordshire
Jun 22nd, 2026
Oxford scientist recognised for AI molecular discovery work.

Oxford scientist recognised for AI molecular discovery work. Ed Pyzer-Knapp, co-founder and chief scientific officer of Oxford-based AI company Xyme (Image: Supplied) A leading scientific mind is being celebrated for his groundbreaking work. Ed Pyzer-Knapp, co-founder and chief scientific officer of Oxford-based AI company Xyme, has been awarded the Royal Society of Chemistry's (RSC) Interdisciplinary Prize. Dr Pyzer-Knapp received the honour for uniting chemistry, physics and AI into a new approach for molecular discovery. He said: "I'm honoured to receive the RSC Interdisciplinary Prize. "The previous recipients are a who's who of interdisciplinary chemistry; it is a privilege to be among them. "The award comes at the right moment. "The work of the last decade is beginning to bear fruit and I know at Xyme, I'm exactly where I need to be to make the most of it." At Xyme, Dr Pyzer-Knapp leads the development of morphogenic AI, a first-of-its-kind AI able to computationally generate purpose-built molecular machines designed to perform specific chemical reactions. Andrew Hopkins, CEO and co-founder of Xyme, praised his colleague for his vision and technical skill. He said: "Ed is one of only a handful of scientists in the world who can move fluently and expertly across quantum physics, chemistry and AI. "That breadth is what makes genuine innovation possible - and this is what teaching AI physics looks like in practice. "Many congratulations to him." The RSC Interdisciplinary Prize has been awarded annually since 1986 to researchers whose work advances knowledge across disciplinary boundaries. Dr Pyzer-Knapp is one of the youngest recipients in the award's history.

Recently Posted Jobs

Sign up to get curated job recommendations

There are no jobs for Xyme right now.

Find jobs on Simplify and start your career today

We update Xyme's jobs every few hours, so check again soon!Browse all jobs