Full-Time
Mechanical Engineer
Posted on 10/31/2025
Periodic Labs
51-200 employees
AI-driven materials discovery and design
No salary listed
Menlo Park, CA, USA
In Person
 Mechanical Engineering (1) |
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- BS in Mechanical Engineering or related field
- 3+ years in mechanical design and vendor-facing manufacturing (machining, sheet metal, plastics)
- Strong CAD (SolidWorks & PDM), GD&T, tolerance analysis, and drawing control
- Experience with fixtures, frames, and enclosures for mechatronic/automation systems
- Comfortable onsite for installs and bring-up in a fast-paced lab environment
- Work with a multidisciplinary team of materials scientists and engineers to translate user and system requirements into mechanical specifications and clear interface definitions
- Lead DFM/DFS with vendors; review drawings, GD&T/tolerance stacks, and materials/finishes
- Define factory and site acceptance test criteria; witness tests and drive punch-list closure
- Support onsite assembly, alignment, and anchoring; coordinate rigging with general contractors and facilities
- Design and own fixtures, guarding, enclosures, and mounting solutions (off-the-shelf and custom)
- Maintain bills of materials, revision control, and as-built documentation
- Incorporate machine-safety and ergonomics; collaborate on interlocks and guarding
- Robotics/automation experience; exposure to P&IDs and utilities interfaces
- FEA simulation for structural and thermal analysis
- Demonstrated accomplishments recognized in your field
Periodic Labs uses AI to model, predict, analyze, and design new materials. Its platform studies material properties and high-throughput data to propose viable compositions, structures, and processing methods that meet performance targets. By training models on large scientific datasets and running simulations, the company speeds up discovery and lowers costs compared with traditional lab work, drawing on founders’ experience from OpenAI and DeepMind. The goal is to accelerate the discovery of materials for clean energy, better semiconductors, and resilient manufacturing, differentiating itself through deep AI expertise applied specifically to materials science and potential collaboration with major AI groups.
Company Size
51-200
Company Stage
Seed
Total Funding
$300M
Headquarters
San Francisco, California
Founded
2025
Simplify's Take
What believers are saying
- Raised $300M seed in September 2025 from a16z, Nvidia, Bezos, and others valuing at $1.5B.
- Secured partnerships with semiconductor makers improving chip heat dissipation since October 2025.
- In talks for hundreds of millions at $7B valuation as of early 2026.
What critics are saying
- DeepMind's GNoME dataset from Cubuk's 2023 project blocks replication in 6-12 months.
- Matlantis launches superior simulations in Q1 2026, undercutting chip partnerships.
- Commerce export controls halt Nvidia AI chip supply in March 2026.
What makes Periodic Labs unique
- Founders Liam Fedus and Ekin Dogus Cubuk combine OpenAI and DeepMind expertise in AI materials science.
- Builds autonomous robotic labs running thousands of experiments daily with gigabytes of unique data.
- Deploys AI agents with physical labs for semiconductors, space, defense, and nuclear fusion applications.
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Benefits
Professional Development Budget
Growth & Insights and Company News
6 month growth
↑ 0%1 year growth
↓ -8%2 year growth
↓ -8%Periodic Labs has raised from a tech industry who's who, including Andreessen Horowitz, Nvidia, Elad Gil, Jeff Dean, Eric Schmidt, and Jeff Bezos.
Venture firm Andreessen Horowitz has agreed to lead a $200 million investment in Periodic Labs, a new startup building artificial intelligence for material science, according to people familiar with the matter.