Internship

Spring 2025 Co-op: Guide RNA Chemistry

Posted on 9/6/2024

Prime Medicine

Prime Medicine

201-500 employees

Gene editing technology for genetic diseases

Biotechnology
Healthcare

No H1B Sponsorship

Belmont, MA, USA

Candidates must be from the local Boston/Cambridge area.

Category
Genomics
Biology Lab & Research
Biology & Biotech
Requirements
  • B.S. candidate in Chemistry/Biochemistry or related subjects.
  • Prior experience working in a chemistry or biochemistry laboratory.
  • A high degree of flexibility and self-motivation in a fast-paced work environment with excellent organizational skills and the ability to prioritize appropriately and meet timelines.
  • Excellent troubleshooting and communication skills.
  • Ability to work independently and within a team.
Responsibilities
  • Support solid-phase synthesis of oligonucleotides using automated DNA/RNA synthesizers.
  • Assist in HPLC purification and UPLC and LCMS analysis of research scale long oligonucleotides.
  • Preparing buffers and solutions for guide RNA purification and analysis.
  • Track and manage chemical, reagent, and consumables inventory and ordering.
  • Assist with maintenance and troubleshooting lab equipment such as synthesizers, speedvacs, lyophilizers, and HPLC instrumentation.
  • Maintain a well-documented electronic laboratory notebook (ELN). Track progress, analyze, interpret, and present data within the team and cross-functional teams.
  • Conducting lab work safely and efficiently, ensuring a safe working environment for colleagues.

Prime Medicine focuses on gene editing, specifically using a technology called Prime Editing to make precise changes to DNA. This technology can identify and fix faulty DNA segments, which helps restore normal genetic function. The company aims to cure, halt, or prevent genetic diseases, providing long-term benefits to patients. Unlike many competitors, Prime Medicine collaborates with research institutions and pharmaceutical companies to advance its technology and bring it to market, generating revenue through licensing and partnerships. The leadership team has significant experience in developing innovative medicines, highlighting the company's commitment to enhancing its capabilities and operations.

Company Stage

IPO

Total Funding

$306.4M

Headquarters

Cambridge, Massachusetts

Founded

2019

Growth & Insights
Headcount

6 month growth

2%

1 year growth

7%

2 year growth

45%
Simplify Jobs

Simplify's Take

What believers are saying

  • Strategic partnerships, like with Bristol Myers Squibb, offer significant financial and developmental benefits.
  • Increased investment interest, such as the $15M from CF Foundation, boosts research capabilities.
  • The $161M PIPE offering provides substantial capital for growth and innovation.

What critics are saying

  • Patent litigation risks could lead to costly legal battles and financial liabilities.
  • Dependency on strategic partnerships may pose risks if collaborations don't meet expectations.
  • Reliance on external funding through PIPE offerings could be risky if market conditions change.

What makes Prime Medicine unique

  • Prime Medicine uses Prime Editing for precise DNA modifications, setting it apart in biotech.
  • The company targets genetic disorders, a vast market with millions of potential beneficiaries.
  • Prime Medicine's leadership includes industry veterans, enhancing its credibility and operational expertise.

Help us improve and share your feedback! Did you find this helpful?

INACTIVE