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Job Title:
Senior Research Technician
Department:
CCC | Comprehensive Cancer Center
The OSUCCC-James Pelotonia Institute for Immuno-Oncology (PIIO) is a comprehensive bench-to-bedside research initiative focused on harnessing the body’s immune system to fight cancer at all levels — from prevention to treatment and survivorship. PIIO researchers work to understand fundamental mechanisms of cancer immunology towards the development of novel immunotherapeutics in the areas of systems immuno-oncology, immunogenomics, cell therapy and translational immuno-oncology.
The PIIO Immune Monitoring and Discovery Platform has launched its Center for Antibody Therapeutics (CAT). We are building a specialized resource dedicated to the discovery, production, and translation of antibody-based cancer therapies. The CAT will leverage cutting-edge technologies to develop monoclonal antibodies, bispecific antibodies, antibody-drug conjugates (ADCs), antibody engineering, and other antibody-based immunotherapies from early stages such as antigen identification, antibody design and production to future clinical grade antibody productions. The center will serve fundamental researchers, clinician scientists, and external partners by providing essential expertise and infrastructure to accelerate immuno-oncology research from basic science discovery to translation and commercialization.
We are seeking a Research Associate to support initiatives within the Center for Antibody Therapeutics. Key responsibilities include:
Research Execution: Conduct assigned experiments independently, including advanced in vitro and in vivo techniques. Perform molecular biology tasks such as DNA/RNA extraction, RT-PCR, and antibody development. Execute protein biochemistry techniques, including antibody/protein purification, SDS-PAGE, ELISA, and flow cytometry. Manage mammalian and bacterial cell cultures, including bispecific antibodies and CAR-T/CAR-NK systems. Conduct in vitro assays such as ADCC, CDC, IncuCyte, RTCA cytotoxicity assays, and Biacore analyses. Develop cancer animal models using techniques like tail vein, intraperitoneal, and subcutaneous injections, small animal imaging, and therapeutic testing.
Data Management: Collect, analyze, and interpret experimental data. Record and consolidate results for evaluation, grant proposals, and publications. Summarize research findings for presentations, manuscripts, and progress reports.
Laboratory Operations: Oversee and maintain laboratory equipment and ensure accurate records of laboratory activities. Monitor and manage research supplies and inventory. Ensure adherence to safety and procedural standards in laboratory operations.
Collaboration and Training: Train and mentor junior research staff, undergraduate, and graduate students in research methods and equipment use. Collaborate with team members to improve existing protocols and develop new experimental procedures.
FUNCTION: Research and Scholarship
CAREER BAND: Individual Contributor - Technical
Required Qualifications
- Bachelor's Degree or equivalent experience.
- 2-3 years of relevant experience required.
- 4-6 years of relevant experience preferred.
Required to include in application:
Cover letter, CV, and contact information of 3 references.
Additional Information:
Additional Information
The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. The Ohio State University is one of the nation’s largest and most comprehensive public universities and a top employer in Ohio.
As one of only 54 designated comprehensive cancer centers in the nation, The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is dedicated to the creation of knowledge in laboratory, clinical and population-based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies – providing tomorrow’s standard of care today. A Cancer-Free World Begins Here.
Location:
Pelotonia Research Center (1040)
Position Type:
Regular
Scheduled Hours:
40
Shift:
First Shift
Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.
Thank you for your interest in positions at The Ohio State University and Wexner Medical Center. Once you have applied, the most updated information on the status of your application can be found by visiting the Candidate Home section of this site. Please view your submitted applications by logging in and reviewing your status. For answers to additional questions please review the frequently asked questions.
The university is an equal opportunity employer, including veterans and disability.
