INACTIVE
Full-Time
Lead – Biotherapeutic Analytics
Accelerates antibody drug discovery with data science
Data & Analytics
AI & Machine Learning
Biotechnology
Senior, Expert
Vancouver, BC, Canada
Requirements
- Leading and managing antibody and other protein analytical characterization activities supporting program advancement and platform development
- Prioritizing and planning the execution of characterization requests, as well as improving request management and communication systems
- Coaching, mentoring, and developing talent within a growing and dynamic team
- Stay scientifically current, driving innovation, and implementing new technologies and workflows to expand and automate antibody characterization capabilities, including leveraging data science and machine learning
- Working closely with CMC teams to develop an innovative approach to accelerate the progression of lead candidate molecules from discovery into early development
- Leading the development and automation of early formulation, developability, and stability assessment workflows to drive lead selection
- Leading the development and implementation of standard operating procedures
- Liaising with partners and communicating project updates and deliverables
- Driving strong collaboration and communication across teams in early Discovery, Bioinformatics, Protein Engineering, Translational, and CMC
- You are a builder who is passionate about developing innovative approaches to the discovery and development of biotherapeutics
- You are strongly self-motivated and can identify project needs and implement solutions
- You are enthusiastic about applying your expertise in analytical characterization to revolutionize the speed and quality of antibody therapeutic discovery
- You take pride in investing time to mentor team members to enhance their skills and drive career development and high performance
- You are an outstanding communicator and teammate
- A PhD in Biochemistry, Biophysics, Biotechnology, Structural Biology or related field with an additional 10+ years of experience, with at least half of that time being in the biopharma or biotechnology industries
- Demonstrated expertise in detailed analytical characterization of antibodies or other protein therapeutics using mass spectrometry, analytical chromatography, capillary electrophoresis, isoelectric focusing, light scattering, or related techniques
- In depth understanding of antibody sequence and structure as well as common modifications and degradation mechanisms
- Experience with antibody stability and developability assessment including both high throughput screening and detailed interrogation of physical and chemical stability risks
- Track record of successful leadership and management, with a focus on developing talent
- Excellent creativity, decision-making, and troubleshooting skills
- Impeccable attention to detail, excellent communication, documentation and technical writing skills
- Great interpersonal skills with the ability to work collaboratively as a member of a cross-functional team
- Experience working in a CMC organization, or familiarity with regulatory issues related to biologics quality would be an advantage
- Familiarity with antibody binding and other mechanistic data from SPR or related technologies would be an advantage
- Experience with automation would be an asset
Company Stage
Series A
Total Funding
$393.1M
Headquarters
Vancouver, Canada
Founded
2012
Growth & Insights
Headcount
6 month growth
↓ -3%1 year growth
↑ 16%2 year growth
↑ 77%INACTIVE