Full-Time

Lead – Biotherapeutic Analytics

AbCellera Biologics

AbCellera Biologics

501-1,000 employees

Accelerates antibody drug discovery with data science

Data & Analytics
AI & Machine Learning
Biotechnology

Senior, Expert

Vancouver, BC, Canada

Requirements
  • Leading and managing antibody and other protein analytical characterization activities supporting program advancement and platform development
  • Prioritizing and planning the execution of characterization requests, as well as improving request management and communication systems
  • Coaching, mentoring, and developing talent within a growing and dynamic team
  • Stay scientifically current, driving innovation, and implementing new technologies and workflows to expand and automate antibody characterization capabilities, including leveraging data science and machine learning
  • Working closely with CMC teams to develop an innovative approach to accelerate the progression of lead candidate molecules from discovery into early development
  • Leading the development and automation of early formulation, developability, and stability assessment workflows to drive lead selection
  • Leading the development and implementation of standard operating procedures
  • Liaising with partners and communicating project updates and deliverables
  • Driving strong collaboration and communication across teams in early Discovery, Bioinformatics, Protein Engineering, Translational, and CMC
  • You are a builder who is passionate about developing innovative approaches to the discovery and development of biotherapeutics
  • You are strongly self-motivated and can identify project needs and implement solutions
  • You are enthusiastic about applying your expertise in analytical characterization to revolutionize the speed and quality of antibody therapeutic discovery
  • You take pride in investing time to mentor team members to enhance their skills and drive career development and high performance
  • You are an outstanding communicator and teammate
  • A PhD in Biochemistry, Biophysics, Biotechnology, Structural Biology or related field with an additional 10+ years of experience, with at least half of that time being in the biopharma or biotechnology industries
  • Demonstrated expertise in detailed analytical characterization of antibodies or other protein therapeutics using mass spectrometry, analytical chromatography, capillary electrophoresis, isoelectric focusing, light scattering, or related techniques
  • In depth understanding of antibody sequence and structure as well as common modifications and degradation mechanisms
  • Experience with antibody stability and developability assessment including both high throughput screening and detailed interrogation of physical and chemical stability risks
  • Track record of successful leadership and management, with a focus on developing talent
  • Excellent creativity, decision-making, and troubleshooting skills
  • Impeccable attention to detail, excellent communication, documentation and technical writing skills
  • Great interpersonal skills with the ability to work collaboratively as a member of a cross-functional team
  • Experience working in a CMC organization, or familiarity with regulatory issues related to biologics quality would be an advantage
  • Familiarity with antibody binding and other mechanistic data from SPR or related technologies would be an advantage
  • Experience with automation would be an asset

Company Stage

Series A

Total Funding

$393.1M

Headquarters

Vancouver, Canada

Founded

2012

Growth & Insights
Headcount

6 month growth

-3%

1 year growth

16%

2 year growth

77%
INACTIVE