Full-Time

North Central Regional Business Manager

Remote USA

Posted on 9/11/2025

Calyxo

Calyxo

201-500 employees

Develops and markets kidney stone devices

Compensation Overview

$165k/yr

+ Bonus + Commission

Remote in USA

Remote

Role is remote in USA; travel up to 60%; company HQ in California but not required to be located there.

Category
Business & Strategy (1)
Required Skills
Sales
Inventory Management
Requirements
  • BS degree with minimum 10 years of relevant medical device sales experience
  • A track record of success in leading teams in medical devices with the majority in sales leadership
  • Preference for candidates with experience launching disruptive technology and urology experience
  • Experience working in early-stage start ups
  • Previous operating room experience including use of fluoroscopy and endoscopy
  • Excellent written and verbal communication skills, including presenting information clearly and effectively to small or large groups
  • Deep experience working and selling into hospitals and ASCs
  • Excellent problem-solving, and decision-making abilities
  • Valid driver’s license issued by the state of residence; good driving record
  • Ability to travel, up to 60% with overnight travel required
  • Responsible for performing all duties in compliance with FDA’s Quality System Regulation (QSR),ISO13485, and all other regulatory requirements applicable to Calyxo, Inc.
  • Willingness and ability to maintain up-to-date hospital credentialing requirements including all required vaccinations and immunizations
Responsibilities
  • Collaborate with the West Coast Area Sales Director and Vice President, Sales to respond to day-to-day sales, strategy, and direction related to CVAC promotional activities.
  • Recruit, develop, lead, and retain territory sales professionals and clinical specialists in accordance with company growth plans.
  • Inspire regional sales teams to continually deliver solid revenue performances in line with company growth expectations.
  • Lead the regional sales team through setting of expectations and monitoring completion of assigned duties and assist in managing resources.
  • Develop direct reports and provide leadership, training and improvement plans as needed.
  • Develop commercial business strategies and tactical plans in conjunction with the Vice President, Sales to lead, manage and track the performance metrics of the regional sales teams.
  • Develop and execute territory and regional-level business development strategies that align with the company’s business strategies.
  • Develop and articulate a unique set of profitable and actionable growth strategies.
  • Ground oneself in sound analysis of competition, market trends, and corporate strengths and weaknesses, translating this data into unsolicited breakthrough proposals.
  • Translate mission and vision into actionable quantitative plans and transfer this vision to regional sales team.
  • Create and execute sales strategies that will help achieve business objectives.
  • Identify process improvements and other efficiencies and leads implementation of identified improvements.
  • Maintain current training to company SOPs and relevant industry regulations.
  • Timely and accurate completion of regional administrative responsibilities including field data entry into SFDC, expense reporting, inventory management and other administrative requests.
  • Establish and maintain customer relationships with key decision makers for the purpose of increasing CVAC adoption.
  • Partner cross-functionally with leadership teams across marketing, customer service, market access, and professional education to develop and optimize the collaboration approach and processes required to scale.
  • Participate in key local, regional, and national tradeshows as needed.
  • Perform other related duties as assigned.

Calyxo, Inc. develops medical devices for kidney stone treatment. Its products are designed for use by urologists in hospitals and clinics to treat kidney stones more effectively, prioritizing patient safety and efficient procedures. The company works closely with leading U.S. urologists to translate clinical needs into devices, focusing on making treatments safer and easier for clinicians. Unlike some competitors, Calyxo emphasizes clinician collaboration and proven clinical relevance in its device development, backed by leadership with startup and product-launch experience. The goal is to improve patient care by delivering advanced devices that help urologists achieve better clinical outcomes and expand the devices’ reach through commercialization to healthcare providers.

Company Size

201-500

Company Stage

Series F

Total Funding

$137.2M

Headquarters

Pleasanton, California

Founded

2016

Simplify Jobs

Simplify's Take

What believers are saying

  • Series F raised $40M led by Ally Bridge Group and Janus Henderson Investors.
  • CVAC system treated over 40,000 patients, advancing toward standard of care.
  • ASPIRE study at AUA showed superior clearance independent of stone burden in 101 patients.

What critics are saying

  • Boston Scientific's LithoClast Trilogy erodes market share via hospital contracts in 12-24 months.
  • Cook Medical's NGage basket undercuts CVAC pricing by 30% in 12-18 months.
  • FDA Class I recall triggers withdrawal due to 5% ureteral perforation risks in 3-9 months.

What makes Calyxo unique

  • CVAC System integrates ureteroscopy, laser lithotripsy, irrigation, and aspiration in one device.
  • SURE procedure with CVAC achieves 97% volumetric stone clearance versus standard URS.
  • Redesigned CVAC received FDA clearance in March 2024 for minimally invasive treatment.

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Benefits

Health Insurance

401(k) Retirement Plan

401(k) Company Match

Paid Vacation

Stock Options

Growth & Insights and Company News

Headcount

6 month growth

1%

1 year growth

2%

2 year growth

8%
StreetInsider
Apr 14th, 2026
Calyxo raises $40M Series F as CVAC kidney stone system treats 40,000 patients

Calyxo, a medical device company focused on kidney stone treatment, has closed a $40 million Series F financing round led by Ally Bridge Group and Janus Henderson Investors. Questa Capital, Avidity Partners and CRG also participated. The funding follows a milestone of 40,000 patients treated with Calyxo's CVAC System, an aspiration-based stone removal device. The system uses irrigation and vacuum aspiration to continuously clear stone fragments during procedures, enabling more complete stone clearance. Proceeds will support commercial expansion, clinical evidence generation through ongoing studies evaluating long-term outcomes, and continued innovation in kidney stone care. The CVAC System received FDA clearance in 2024 and is positioned as an all-in-one solution for minimally invasive kidney stone removal.

Business Wire
May 14th, 2024
Study Presented At Aua Shows Superior Kidney Stone Clearance Rates For Sure Procedure Using Calyxo’S Cvac System Vs Standard Urs

PLEASANTON, Calif.--(BUSINESS WIRE)--Calyxo, Inc., a medical device company developing innovative solutions for patients with kidney stones, has announced that positive study results for its CVAC System were presented last week at the American Urological Association (AUA) Annual Meeting in San Antonio. The CVAC System, a revolutionary technology that is designed for complete kidney stone removal, was the focus of the prospective, randomized, multi-center ASPIRE study, which compared the safety and efficacy of steerable ureteroscopic renal evacuation (SURE) vs ureteroscopy (URS) with basketing. The 30-day results of the ASPIRE study were presented at the AUA Meeting by urologist Thomas Chi, MD of the University of California, San Francisco. In 101 patients, SURE demonstrated statistically superior stone clearance and significantly lower residual stone volume compared to standard URS. Unlike standard URS, the CVAC System achieved these results independent of baseline stone burden. Safety was comparable between groups

Business Wire
Mar 26th, 2024
Calyxo Announces Fda Clearance For New, Redesigned Cvac System

PLEASANTON, Calif.--(BUSINESS WIRE)--Calyxo, Inc., a medical device company developing innovative solutions for patients with kidney stones, announced that it has received FDA clearance for its new, redesigned CVAC System, which enables a minimally invasive approach to kidney stone treatment. More than 50 procedures have already been completed by 12 urologists with the new CVAC System, yielding strong patient outcomes and consistently positive physician feedback. Clinical studies have shown that residual stone fragments are associated with a 20%-44% incidence of post-procedure problems, including pain, infection, emergency department visits, hospitalization and need for retreatment. Steerable ureteroscopic renal evacuation (SURE) using the original CVAC Aspiration System has been used to successfully treat more than 1,500 patients in the U.S., demonstrating that vacuum aspiration of stone fragments improves clinical outcomes, with 97% volumetric stone clearance and a high likelihood of avoiding the need for a secondary or more invasive procedure (according to clinical study data collected in patients treated with the device)

FinSMEs
Dec 12th, 2023
Calyxo Raises $50M in Series D Funding

Calyxo, a Pleasanton, CA-based medical device company developing next-generation treatment solutions for patients with kidney stones, raised $50M in Series D funding.

Questa Capital
Jul 6th, 2022
Questa Capital invests into Calyxoinc in $32.7M

Calyxo, Inc., a medical device company focused on improving care for patients with kidney stones by delivering next generation treatment solutions, has announced the closing of a $32.7 million Series C financing round led by Questa Capital and CRG.

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