Full-Time

Senior Research Associate

Upstream Process Development, Cell Culture

Updated on 5/8/2024

Vir Biotechnology

Vir Biotechnology

501-1,000 employees

Develops treatments for infectious diseases

Data & Analytics

Compensation Overview

$93,000 - $122,000Annually

+ Bonus + Equity

Senior

San Francisco, CA, USA

Required Skills
Data Analysis
Requirements
  • Minimum of BS/MS with 6+ years industrial
  • Proven understanding of cGMP antibody upstream process development and production using CHO host cell expression systems at bench or pilot scale
  • Hands-on experience with mammalian cell culture, aseptic techniques, understanding of biochemical engineering concepts, and biochemical pathways
  • Experience in developing and improving scalable fed-batch, transfection, and perfusion upstream processes in PD setting
  • Familiar with bioreactor scale-up concepts and have a proven track record for scaling-up processes to disposable/stainless bioreactors
  • Ability to use Design of Experiments in JMP, Design Expert, or other for statistical experimental design, and data analysis
  • Direct pilot/cGMP scale biomanufacturing experience is strongly preferred
  • Good documentation practices (GDP) experience and experience writing standard operating procedures, batch records, and technical reports is preferred
Responsibilities
  • Develop scalable processes such as mammalian cell culture and harvest processes for upstream cell culture development
  • Designs scientifically rigorous experiments using statistical DoE where applicable and execution of experiments, analyze and interpret data to further craft next studies
  • Lead and implement experiments in the design, development, optimization and scale-up of protein production processes in suspension cell culture systems
  • Works closely with project leads to draft standard operating procedures and master batch records for pilot scale batches
  • Summarizes bench and pilot scale study results, reviews batch production records and drafts production summary reports
  • Supports the creation and review of tech transfer protocol, supports the technical transfer of upstream unit operations to external manufacturing organizations
  • Supports the design and analyses of early and late stage process development and process characterization studies
  • Provides oral project status updates and presentations to internal or external shareholders
  • Aligns best practices and new technologies with needs of process development and manufacturing departments
  • Works closely with Environmental Health and Safety and Quality to ensure lab work is performed in safe and compliant manner

Vir Biotechnology is at the forefront of combating infectious diseases, leveraging advanced technologies such as a proprietary monoclonal antibody platform along with machine learning and artificial intelligence. This focus not only prioritizes public health but also fosters a culture of continuous innovation and commitment to scientific excellence. Working here means contributing to pivotal developments that address some of the most pressing global health challenges today, such as influenza, HIV, and COVID-19, in an environment that values cutting-edge research and a collaborative spirit.

Company Stage

Grant

Total Funding

$908.6M

Headquarters

San Francisco, California

Founded

2016

Growth & Insights
Headcount

6 month growth

-4%

1 year growth

-1%

2 year growth

22%

Benefits

Comprehensive healthcare coverage

Employer matched 401(k)

Employee stock purchase plan

Childcare assistance

Tuition reimbursement