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Scientist – CRISPR Specificity Screening
Confirmed live in the last 24 hours
Alameda, CA, USA
Experience Level
Desired Skills
Data Analysis
  • Experience with a range of assay development in next-generation sequencing techniques, including both library preparation and data analysis
  • Depth of experience with mammalian tissue culture techniques
  • Experience in Python programming, unix command line, version control systems (e.g. git), bioinformatic and computational biology toolkits applied to NGS analysis
  • Ability to work collaboratively in a fast-paced, interdisciplinary research team
  • Excellent prioritization and organization skills
  • Work closely with Scribe's teams to develop novel assays and optimize existing ones to assess the potential off-target editing effects of CRISPR-based therapies across a range of enzymes, targets, and delivery systems
  • Collaborate across pre-clinical therapeutic groups both within the company and externally to drive rapid advancement of new targets and molecules
  • Ensure high quality data generation through proper assay validation and qualification
  • Assume project responsibilities and effectively present updates, and communicate research plans and timelines to the senior leadership team internally and partners externally
  • Critically evaluate experimental data and communicate scientific findings as verbal presentations and written reports
  • Mentor junior team members
Desired Qualifications
  • PhD in molecular biology, cell biology, genetics, bioengineering or related field. A postdoc and/or 1+ years industry experience is a plus
  • Experience with CRISPR-Cas gene editing systems and delivery technology
  • Background in DNA repair/DNA damage response pathways
  • Familiarity with current methods of on-target, off-target editing assessment
  • Track record of methods development and innovation
Scribe Therapeutics

11-50 employees