Full-Time

Principal Architect Enterprise Architecture

Posted on 11/7/2025

Cardinal Health

Cardinal Health

Distributes pharmaceuticals and medical products globally

Compensation Overview

$116.5k - $207.8k/yr

+ Bonus

Company Does Not Provide H1B Sponsorship

Remote in USA + 1 more

More locations: Dublin, OH, USA

Hybrid

Category
IT & Security (1)
Requirements
  • Degree in Computer Science, Software Engineering, or equivalent technical degree preferred with experience in software implementation and development
  • 10+ years of hands-on development experience with 5+ years as a lead developer /architect preferred
  • Experience with enterprise financial processes within OTC and STP functions in SAP or Oracle ERP solutions
  • Has demonstrated experience designing architectures of complex distributed systems, and have lead teams through the development of those systems
  • Significant hands-on experience across the entire enterprise technology stack
  • Proficiency in ERP platforms (SAP, Oracle Fusion or Workday highly preferred)
  • Understanding of data modelling in modern relational, graph, NoSQL databases and knowledge of vector databases for solutioning using AI
  • Experience with RESTful web services and API design
  • Experience architecting solutions with client-side web development and UI frameworks (Angular/React etc.)
  • Significant experience with distributed computing and event driven architecture
  • Proficiency in application/platform security and working with security architects to validate solution requirements for security and data privacy
  • Ability to travel as needed (~5 - 10%) and if local to Columbus, Ohio, ability to work in office ~2x days per week
  • Understanding of Applied Artificial Intelligence and Gen AI
  • Understanding of data modelling in modern relational, graph, NoSQL databases and knowledge of vector databases for solutioning using AI
  • Proficiency in ERP platforms (SAP, Oracle Fusion or Workday highly preferred)
Responsibilities
  • Leads the identification and analysis of business drivers to derive enterprise business, information, technical and solution architecture requirements; analyzing industry, technology, and market trends to determine their potential impact on the enterprise
  • Partners with Enterprise teams to develop multi-year IT strategy for Enterprise Functions, Finance Operations, Nuclear, OptiFreight, and At Home Solutions business divisions.
  • Bring experience to challenge status quo and devise better ways to achieve business objectives
  • Leads technical due diligence and road mapping for strategic partnerships, third party partners, mergers, and acquisitions
  • Leverages relationships across the enterprise to drive agreement via partnership and collaboration with stakeholder group comprising Tech Strategy & Execution (Tech Strategy, EA, PMO, Vendor Management, Strategic initiatives), Business, Solution Owners, COEs, Infrastructure & Shared Services and Security to develop and deploy comprehensive solution architectures.
  • Design and architect next generation enterprise architectures across multiple enterprise architecture domains including Business, Application, Data & Technology architecture to achieve a low TCO, solution agility and speed to market.
  • Leads the development of technology transitions or architecture evolutions by creating foundational examples of working solutions and mentors teams on how to build on those examples
  • Owns software/platform technologies and patterns, techniques, and enable outcomes of Non-Functional Requirements (scalability, availability, performance, security, and operational insight)
  • Acts as Mentor and Coach for teams and individuals on architecture, strategy, solution owner, engineering, and COE teams
  • Leads teams in the delivery practices of zero-downtime deployments, continuous delivery, build pipelines, and techniques for team autonomy
  • Joins teams to assist with / lead development activities in times of need to solve challenging programs or to provide extra development capacity
Desired Qualifications
  • Knowledge of Finance, Customer Service, Transportation, Medical Product and Nuclear Health businesses. Knowledge of Revenue Cycle Management a plus.
  • Ability to travel as needed (~5 - 10%) and if local to Columbus, Ohio, ability to work in office ~2x days per week
  • Bonus eligible: Yes
  • Anticipated salary range: $116,500- $207,755
  • Experience with enterprise financial processes within OTC and STP functions in SAP or Oracle ERP solutions
  • Understanding of data modelling in modern relational, graph, NoSQL databases and knowledge of vector databases for solutioning using AI
  • Proficiency in ERP platforms (SAP, Oracle Fusion or Workday highly preferred)

Cardinal Health distributes pharmaceuticals and manufactures medical and laboratory products for hospitals, clinics, and pharmacies worldwide. The company operates a global logistics network to deliver supplies while providing data tools that help healthcare facilities track inventory and improve operational efficiency. Unlike many niche suppliers, Cardinal Health combines 50 years of experience with a massive scale that covers both the physical supply chain and the software needed to manage it. Its goal is to streamline the healthcare supply chain to ensure providers have reliable access to essential products while reducing costs and improving patient care.

Company Size

N/A

Company Stage

N/A

Total Funding

$270.6M

Headquarters

Dublin, California

Founded

1971

Simplify Jobs

Simplify's Take

What believers are saying

  • Majority stake in GI Alliance in November 2024 accelerates gastroenterology growth.
  • Acquired Advanced Diabetes Supply Group in November 2024 boosts at-Home Solutions.
  • Added Solaris Health urology MSO in August 2025 to Specialty Alliance platform.

What critics are saying

  • McKesson erodes specialty share with superior pharmacy analytics within 12-24 months.
  • Cencora undercuts generics pricing, squeezing margins in 6-12 months.
  • DEA quotas cut $500M opioid revenue comprising 20% sales in 3-6 months.

What makes Cardinal Health unique

  • Acquired Specialty Networks in January 2024 for multi-specialty GPOs in urology and gastroenterology.
  • Launched Kendall DL™ Multi System in June 2025 for continuous vital signs monitoring.
  • Expanded Actinium-225 production in April 2026 for novel cancer therapies.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Paid Vacation

Health Savings Account/Flexible Spending Account

401(k) Retirement Plan

401(k) Company Match

Short- and Long-term Disability Coverage

Paid Parental Leave

Wellness Program

Company News

PR Newswire
Jan 31st, 2024
Cardinal Health To Acquire Specialty Networks And Its Pps Analytics Platform, A Technology Enabled Multi-Specialty Group Purchasing And Practice Enhancement Organization In Urology, Rheumatology And Gastroenterology

Transaction creates increased clinical and economic value for 11,500 specialty providers, including more than 7,000 physicians across 1,200 independent physician practices. Transaction creates platform for Cardinal Health expansion across specialty therapeutic areas. Transaction enhances capabilities of Cardinal Health Specialty and supports ongoing build of Navista™ NetworkDUBLIN, Ohio, Jan. 31, 2024 /PRNewswire/ -- Cardinal Health (NYSE: CAH) announced today that it has entered into a definitive agreement to acquire Specialty Networks, a technology-enabled multi-specialty group purchasing and practice enhancement organization for $1.2B in cash. Specialty Networks creates clinical and economic value for independent specialty providers and partners across multiple specialty GPOs: UroGPO, Gastrologix and GastroGPO, and United Rheumatology

intelligence360
Mar 7th, 2023
Cardinal Health To Spend $3,100,000.00 To Occupy 3,794 Square Feet Of Space In Indianapolis Indiana.

Cardinal Health to spend $3,100,000.00 to occupy 3,794 square feet of space in Indianapolis Indiana. Cardinal Health to spend $3,100,000.00 to occupy 3,794 square feet of space in Indianapolis Indiana.Indianapolis, Indiana — According to state and local economic development sources, Cardinal Health plans to invest $3,100,000.00 to build out 3,794 square feet of new space in Indianapolis. The company plans to occupy the new space at 7736 Zionsville Rd in Indianapolis, on or about September 1, 2023. According to the company website Cardinal Health is a distributor of pharmaceuticals, a global manufacturer and distributor of medical and laboratory products, and a provider of performance and data solutions for healthcare facilities. With operations in more than 30 countries and approximately 44,000 employees globally, Cardinal Health is essential to care. We are navigating the complexities of healthcare and providing scaled solutions to help our customers thrive in a changing world

GlobeNewswire
Jul 26th, 2022
RxLive Raises $5 Million Series A to Deliver Population Health Telepharmacy Solutions for At-Risk Patients

Digital Health Startup Is Tackling Medication Mismanagement, a $500 Billion Problem...

PR Newswire
Jan 10th, 2022
Medically Home Announces a $110 Million Strategic Investment Led by Baxter International Inc., Global Medical Response and Cardinal Health to Advance Leadership in Hospital-Level Patient Care at Home

/PRNewswire/ -- Medically Home today announced a new, $110 million round of funding from strategic investors including Baxter International Inc., Global...

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