Full-Time

Software Engineering Lead

AstraZeneca

AstraZeneca

10,001+ employees

Global pharmaceutical company developing prescription medicines

No salary listed

Chennai, Tamil Nadu, India + 1 more

More locations: Bengaluru, Karnataka, India

In Person

On-site in Bangalore or Chennai, India.

Category
AI & Machine Learning (1)
Required Skills
LLM
Pinecone
Microsoft Azure
FastAPI
Python
React.js
NoSQL
SQL
RAG
TypeScript
AWS
Terraform
REST APIs
Flask
LangChain
DevOps
Django

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Requirements
  • Experience: 10+ years in software engineering; 5+ years in a Technical Lead role.
  • Core Stack: Python (FastAPI, Flask, or Django) and React (TypeScript).
  • AI Specialization: Hands‑on LLM integration, prompt engineering, and orchestration frameworks (e.g., LangChain, AutoGen, or LlamaIndex).
  • Data Architecture: Strong SQL/NoSQL skills, plus experience with Vector Databases (e.g., Pinecone, Weaviate, or Milvus) for semantic retrieval.
  • Cloud & Infra: Expert-level Azure or AWS experience. Proficiency in IaC (Terraform/Bicep) and building AI-ready CI/CD pipelines.
  • Integration: Expertise in REST, event-driven architectures, and emerging protocols like (MCP).
Responsibilities
  • Architectural Leadership & AI Strategy: Define and uphold engineering patterns for Python, React, and cloud services. Lead the move from traditional logic to Agentic workflows, ensuring custom solutions are "AI-first" by design.
  • AI-Augmented SDLC: Drive the integration of AI throughout the software lifecycle. Implement Model Context Protocol (MCP) to bridge the gap between local development environments and LLM-based assistants.
  • Engineering Quality & Governance: Reinstate structured code reviews with a focus on AI Governance. Establish quality gates that cover not just security and performance, but also LLM observability, hallucination mitigation, and bias detection.
  • Agentic Productivity: Mentor and upskill junior engineers on Agentic AI tools (GitHub Copilot, Cursor, Agent Builder). Shift the team’s focus from manual boilerplate to high-level system design.
  • FinOps for AI: Optimize cloud architectures for cost-efficiency. Lead AI FinOps by balancing token usage, model selection (SMMs vs. LLMs), and inference costs against business outcomes.
  • Solution Shaping & RAG Patterns: Partner with Business partners to scope work using RAG (Retrieval-Augmented Generation) and semantic search patterns to unlock value from enterprise data.
Desired Qualifications
  • Enterprise Platforms: Experience integrating AI agents with Workday (HCM) or Power Platform.
  • AI Governance: Familiarity with compliance-aware development in regulated environments (e.g., Pharmaceutical or Finance), focusing on data privacy in AI models.
  • Containerization: Mastery of Docker and Kubernetes for deploying scalable AI microservices.
  • DevSecOps: Advanced understanding of secrets management and "Security for AI" (OWASP Top 10 for LLMs).

AstraZeneca develops and markets prescription medicines and vaccines for global health, focusing on oncology, cardiovascular/metabolic, respiratory, and infectious diseases. Its products work by targeting specific biological pathways or cells to treat diseases or prevent infections, using small-molecule drugs, biologics, and vaccines. The company differentiates itself through its dual heritage from Sweden and the UK, a broad pipeline, and strong R&D with collaborations to move from discovery to patient access across multiple therapeutic areas. Its goal is to improve people’s health by discovering, developing, and delivering medicines and vaccines worldwide.

Company Size

10,001+

Company Stage

IPO

Headquarters

Cambridge, United Kingdom

Founded

1913

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Simplify Jobs

Simplify's Take

What believers are saying

  • EU approved Datroway for metastatic TNBC in 2026, expanding oncology revenue momentum.
  • Canada approved Fasenra for HES in 2026, adding a rare-disease growth avenue.
  • CSPC and AstraZeneca keep deepening partnerships in 2026, including peptides, siRNA, and manufacturing.

What critics are saying

  • Reuters on August 5, 2026 said no AstraZeneca-BMS talks exist, exposing credibility damage.
  • Ultomiris missed its main Phase III goal in 2026, worsening AstraZeneca’s late-stage pipeline volatility.
  • Breast-cancer setback against U.S. regulators threatens Etcamah launch timing and 2030 revenue execution.

What makes AstraZeneca unique

  • Pascal Soriot built AstraZeneca into oncology-led growth machine since 2012, now targeting $80 billion revenue.
  • The August 2026 NYSE move strengthens U.S. capital-market access and commercial credibility.
  • CSPC’s August 2026 biologics JV gives AstraZeneca China manufacturing leverage for global supply.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

401(k) Retirement Plan

Paid Vacation

Paid Holidays

Flexible Work Hours

Growth & Insights and Company News

Headcount

6 month growth

3%

1 year growth

3%

2 year growth

5%
Yahoo Finance
Aug 11th, 2026
Hedge funds boost AstraZeneca stake to $5.5B despite pipeline setbacks

AstraZeneca topped second-quarter profit expectations with core earnings per share of $2.63 versus the $2.48 analysts expected. The firm reiterated its target of $80 billion in annual revenue by 2030. However, the quarter brought fresh pipeline setbacks. Its rare disease drug Ultomiris missed its main goal in a late-stage trial, the latest in a string of disappointments that also includes an earlier heart drug trial failure and a breast cancer drug application that US regulators rejected. Oncology revenue rose 15%, with cancer drugs Tagrisso and Imfinzi leading growth. AstraZeneca won EU approval for its breast cancer drug Etcamah, though a US regulatory panel rejected it in May. Hedge fund holdings increased to 56 funds in Q1 2026, up from 52 the previous quarter.

Associated Press
Aug 10th, 2026
Canada approves Fasenra for hypereosinophilic syndrome, cutting flare risk by 65%

Health Canada has approved Fasenra (benralizumab) as an add-on treatment for patients aged 12 and older with hypereosinophilic syndrome (HES), a rare disorder characterised by elevated eosinophil levels that can cause organ damage. The approval follows the NATRON Phase III trial, which showed benralizumab reduced the risk of disease flares by 65% compared to placebo. In the study, 19.4% of patients receiving benralizumab experienced disease worsening versus 42.4% in the placebo group. HES affects an estimated 2,000 to 2,500 people in Canada. The condition involves persistently high levels of eosinophils in the blood, potentially leading to progressive organ damage and proving fatal if untreated. Fasenra is administered subcutaneously every four weeks. The drug is also approved in Canada for severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis.

Pharmaceutical Executive
Aug 5th, 2026
CSPC Pharmaceutical & AstraZeneca form joint venture for biologics manufacturing in China.

CSPC Pharmaceutical & AstraZeneca form joint venture for biologics manufacturing in China. CSPC Pharmaceutical and AstraZeneca have formed a 51:49 joint venture to build a biologics manufacturing facility in Shijiazhuang. CSPC Pharmaceutical Group and AstraZeneca have entered into a joint venture contract to build a new-generation biologics manufacturing facility in Shijiazhuang, China. The venture marks the third strategic agreement the two companies have struck in as many years, and is expected to focus on the manufacturing and supply of mutually agreed biologics drug substances for global markets, with the companies contributing capital at a 51:49 equity ratio in favor of CSPC.[1] What are the terms of the joint venture? Under the terms of the joint venture contract, CSPC and AstraZeneca will jointly manage construction along with day-to-day operations, drawing on their respective strengths. As the business develops, production capacity scales up, and commercial demand grows, the companies say they will explore incorporating additional products into the joint venture's scope.[1] The agreement remains subject to customary closing conditions, including regulatory approvals. The joint venture is designed to combine CSPC's AI-driven Good Manufacturing Practice system and its pharmaceutical manufacturing construction and operational capabilities with AstraZeneca's expertise in global quality standards and supply chain management.[1] The initial business scope centers on biologics drug substances, with both companies committing to delivering high-quality medicines to patients worldwide. Why does this matter for CSPC's global ambitions? CSPC says the collaboration reflects strong recognition of its modernized manufacturing system, quality management capabilities, and industrial-scale execution by a leading global multinational pharmaceutical company. The company frames the joint venture as extending its internationalization path from "going global with products and technologies" to "going global with manufacturing systems and supply chain capabilities."[1] As global pharmaceutical companies continue to optimize research, manufacturing, and supply chain footprints, CSPC argues that high-quality, efficient, and sustainable manufacturing and supply capabilities are becoming a core competency across the global innovative drug value chain, laying groundwork for more of its innovative drug products to enter international markets. Previous deals between CSPC and AstraZeneca. The manufacturing joint venture builds on a fast-deepening relationship between the two companies. In June 2025, AstraZeneca and CSPC entered a to discover and develop pre-clinical oral candidates against high-priority targets across multiple chronic indications, including a pre-clinical small molecule oral therapy for immunological diseases.[2] The research is being carried out by CSPC in Shijiazhuang using its AI-driven, dual-engine drug discovery platform. As part of the agreement, CSPC received an upfront payment of $110 million and eligiblity for up to $1.62 billion in development milestone payments and upwards of $3.6 billion in sales milestone payments.[2] More recently, the companies struck a for obesity and type 2 diabetes across eight programs, four of which will progress initially using CSPC's AI-driven peptide drug discovery platform and its proprietary LiquidGel once-monthly dosing technology.[3] AstraZeneca secured exclusive global rights outside China to CSPC's once-monthly injectable weight management portfolio, including SYH2082, a long-acting GLP1R/GIPR agonist progressing into Phase I, and three preclinical programs.[3] What comes next? With the biologics manufacturing joint venture still pending regulatory clearance, CSPC says it believes the new facility will strengthen its ability to meet international manufacturing and supply demand while supporting the broader pipeline of products emerging from its expanding partnership with AstraZeneca.

Alpro Pharmacy Sdn Bhd
Aug 4th, 2026
Are your kidneys OK+ official launch | together with AstraZeneca.

Are your kidneys OK+ official launch | together with AstraZeneca. AreYourKidneysOK+? Officially Launched to Advance Early Detection in Cardio-Kidney-Metabolic Care | While diabetes, chronic kidney disease (CKD), and cardiovascular disease are widely recognised, fewer people are aware of hyperkalemia (high potassium levels), a serious condition that can occur alongside these diseases and increase the risk of life-threatening complications. That's why raising awareness and encouraging early screening are essential to helping more Malaysians understand their risks and seek timely care. Today, together with AstraZeneca, Alpro Pharmacy is proud to launch AreYourKidneysOK+?, a kidney health awareness initiative dedicated to advancing early detection and improving awareness of cardio-kidney-metabolic (CKM) health. | Through this initiative, 12,550 subsidised blood test screenings will be made available to support earlier risk detection through key health markers, including blood sugar, cholesterol, kidney function, and potassium levels. The programme is further complemented by a dedicated online hyperkalemia education platform and teleconsultation services, making trusted health information, professional guidance, and follow-up care more accessible than ever. The launch also featured an expert panel discussion, "Diabetes Risk to Kidney Protection: Supporting Earlier Recognition of Hyperkalemia Risk," where a nephrologist, an endocrinologist, and a pharmacist shared insights on multidisciplinary care, patient empowerment, and the importance of early intervention. Attendees also explored a series of interactive hyperkalemia educational stations by AstraZeneca, offering engaging learning experiences that reinforced the importance of kidney health and early detection. Because every screening is more than just a test, it is an opportunity to detect risks earlier, take action sooner, and protect your kidneys, your heart, and your future. | | Learn more: https://edu.alpropharmacy.com/a/?a=NzY= #AlproPharmacy #AreYourKidneysOK+ #KidneyHealth #CKDAwareness #Hyperkalemia #CardioKidneyMetabolic #PreventiveHealthcare #EarlyDetection #AstraZeneca

Yahoo Finance
Aug 3rd, 2026
AstraZeneca shares plunge 8%, wiping out $22B after Bristol Myers merger rumours

AstraZeneca and Bristol Myers Squibb have held initial discussions about a potential merger that would create a combined entity worth nearly $400 billion, according to reports citing people familiar with the matter. The market reaction was sharply negative, with AstraZeneca shares falling more than 8%, wiping out roughly $22 billion in market value, whilst Bristol Myers dropped almost 1.5%. The deal would strengthen AstraZeneca's cancer and cardiovascular drug portfolios, which accounted for 44% and 22% respectively of its $59 billion revenue last year. Bristol Myers faces upcoming patent losses for key drugs including immunotherapy Opdivo and blood thinner Eliquis. Analysts questioned the strategic rationale, noting AstraZeneca's recent success under CEO Pascal Soriot.