Summer Intern
CMC Process Development
Posted on 2/27/2024
INACTIVE
Arrowhead Pharmaceuticals

201-500 employees

RNAi-based gene-silencing therapeutics
Company Overview
Arrowhead Pharmaceuticals stands out in the biopharmaceutical industry through its focused application of RNA interference (RNAi) mechanisms to develop targeted therapies for genetic diseases, exemplified by its candidate plozasiran aimed at reducing ApoC3 protein levels to manage severe hypertriglyceridemia. The company's proprietary TRiM platform demonstrates a competitive edge by enabling tissue-specific gene silencing, which has shown promise in early clinical trials, such as the AROAPOC3-2001 study, to improve lipid levels safely and effectively. Arrowhead's approach to drug development not only streamlines manufacturing and potentially reduces costs but also positions the company as a leader in RNAi therapeutics, with ongoing research that could transform treatment paradigms for patients with lipid disorders.
Biotechnology

Company Stage

N/A

Total Funding

$899.9M

Founded

2004

Headquarters

Pasadena, California

Growth & Insights
Headcount

6 month growth

10%

1 year growth

32%

2 year growth

63%
Locations
Fitchburg, WI, USA
Experience Level
Intern
CategoriesNew
Data Engineering
Data Management
Data & Analytics
Requirements
  • Currently enrolled student at an Accredited University or College and majoring in Chemistry or Engineering
  • Excellent verbal and written communication skills
  • Strong problem-solving skills
  • Eagerness to learn new techniques
  • Ability to work in a lab setting for prolonged periods of time
  • Ability to wear personal protective equipment as required
  • Must be able to lift 15 pounds at a time
Responsibilities
  • Work closely with a senior scientist to execute and develop a scale down model for a new Manufacturing process
  • Perform reactions related to oligonucleotide synthesis
  • Analyze oligonucleotides using standard analytical methods (LC-MS)
  • Maintain a well-documented laboratory notebooks
  • Present findings from the summer research project to the PD team during group meeting(s)