Full-Time

Vice President

Scientific Data Strategy

Posted on 3/8/2025

Chan Zuckerberg Initiative

Chan Zuckerberg Initiative

501-1,000 employees

Philanthropic tech foundation funding science, education

Compensation Overview

$363k - $519.2k/yr

+ Bonus + Equity + Other Compensation

San Carlos, CA, USA

Hybrid

Bay Area relocation assistance available.

US Citizenship, US Top Secret Clearance, Canada Citizenship, Canada Top Secret Clearance, UK Citizenship, UK Top Secret Clearance Required

Category
Data & Analytics (2)
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Requirements
  • Extensive leadership experience building and managing diverse data teams (e.g., funding, partnership, engineering, data science, AI/ML specialists) within large-scale, fast-paced, high performance organizations.
  • Deep experience with biological data types across omics platforms and imaging modalities
  • Strong background in computational biology, bioinformatics, and machine learning applications
  • Demonstrated success managing complex, multi-modal biological datasets, production pipelines in the contexts of AI model development as well as the driving experimental research
  • Forward-looking mindset, with the ability to anticipate emerging technologies and translate them into innovative data strategies and products that propel biomedical research forward.
  • Experience building and leading a world-class team of data scientists, engineers, and analysts. Ability to identify and mentor top talent in the field, fostering a collaborative and innovative culture that empowers teams to push the boundaries of data science and AI in biomedical research.
  • Experience implementing data governance in collaborative research settings
  • History of balancing immediate operational needs with strategic vision
  • Ability to navigate and unify diverse internal and external stakeholders.
  • Strong communication skills to promote CZI's progress and discoveries internally and externally.
  • Deep understanding of scientific assays and domain applications necessary to provide robust partnership and oversight to interdisciplinary teams.
  • Understanding of comparative biology and cell type conservation across species
  • Familiarity with model organism systems and translational research
  • Knowledge of current limitations in biological data generation and analysis
  • Exceptional collaboration and communication skills, demonstrated by successful cross-functional and external stakeholder engagements, including partnerships with academic institutions, industry, and the broader research community.
  • Proven track record of delivering high-impact scientific data products to both internal and external stakeholders, ensuring research teams can readily access, explore, and leverage data assets.
  • Ability to make data-driven decisions under uncertainty while maintaining scientific integrity
  • Skill in communicating complex technical concepts to diverse stakeholders
  • Experience navigating build-buy-partner decisions for technical infrastructure
Responsibilities
  • Develop a vision and strategy for data as a strategic advantage in CZI's AI leadership in the biological sciences.
  • Establish strategy and implementation (i.e., architecture, standards) to ensure CZI's datasets are AI-ready and interoperable across our Grand Challenges.
  • Develop and implement data governance frameworks that balance scientific flexibility with the consistency needed for machine learning applications.
  • Establish and iterate on CZI’s data strategy in close collaboration with Grand Challenge leaders, ensuring alignment with scientific objectives and emerging research opportunities
  • Identify critical data gaps and prioritize data generation efforts to maximize scientific value and model performance; develop roadmaps for data acquisition that align with both immediate project goals and long-term vision
  • Actively procure, generate, and manage high-value datasets, forging partnerships and leveraging publicly available data to maximize research potential.
  • Oversee the design and deployment of robust data infrastructure, architectures and pipelines that drive data interoperability in the CZI ecosystem and ensure security, scalability, and compliance with regulatory requirements
  • Implement robust quality control mechanisms ensuring data reliability across distributed collection efforts;
  • Develop and promulgate metadata standards and integration frameworks that enable cross-species comparison of cell types and biological mechanisms to benefit internal and external scientific communities.
  • The data leader will build and direct a team of data scientists, engineers, and bioinformaticians who interface directly with experimental groups
  • Foster a culture that values both scientific rigor and operational excellence in data management that spans molecular, morphological and temporal data such as emerging 4D imaging methods.
Chan Zuckerberg Initiative

Chan Zuckerberg Initiative

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The Chan Zuckerberg Initiative channels philanthropy and technology to speed progress in science, education, and community development by funding grants, making strategic investments, and building technology tools. It funds and builds practical tools such as personalized learning platforms and AI-assisted research tools, supports researchers, educators, and communities through grants and partnerships, and manages an endowment. It combines grant-making, investments, and technology development across education, science, and community work, emphasizes interdisciplinary collaboration, and uses AI to accelerate discovery while aligning tech with social goals. Its goal is to build a better future by expanding human potential and advancing equality through science, education, and community support.

Company Size

501-1,000

Company Stage

N/A

Total Funding

$2.7B

Headquarters

Menlo Park, California

Founded

2015

Simplify Jobs

Simplify's Take

What believers are saying

  • $10M Washington Research Foundation grant boosts Seattle Synthetic Biology Hub.
  • Billion Cells Project partners with Psomagen and Ultima Genomics for AI datasets.
  • New Imaging Biohub combines CZ Biohub SF and Imaging Institute expertise.

What critics are saying

  • Gates Foundation's $9B 2026 donations lure talent from CZI Biohub.
  • 70 job cuts and East Palo Alto school closure erode local support.
  • FTC antitrust probes halt Meta-CZI AI overlap in 12 months.

What makes Chan Zuckerberg Initiative unique

  • CZI pivots to AI-powered Biohub network curing all diseases by 2036.
  • Acquired EvolutionaryScale integrating AI algorithms into Biohub science.
  • Launched GREmLN model advancing genetics research with AI.

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Benefits

401(k) Company Match

401(k) Retirement Plan

Paid Vacation

Family Planning Benefits

Relocation Assistance

Mental Health Support

Wellness Program

Flexible Work Hours

Student Loan Assistance

Childcare Support

Company News

Fortune
Feb 1st, 2026
The Chan Zuckerberg Initiative cut 70 jobs as the Meta CEO's philanthropy goes all in on mission to 'cure or prevent all disease'

The Chan Zuckerberg Initiative cut 70 jobs as the Meta CEO's philanthropy goes all in on mission to 'cure or prevent all disease' The Chan Zuckerberg Initiative is making big changes, and it started 2026 with some job cuts to recalibrate and refocus its efforts on AI-powered biomedical research. The philanthropic organization, formed by Meta cofounder and CEO Mark Zuckerberg and his wife, Dr. Priscilla Chan, is cutting about 70 jobs, or roughly 8% of its workforce, a CZI spokesperson confirmed to Fortune. The layoffs happened primarily at the organization's Redwood City headquarters in San Mateo, Calif. In 2025, Zuckerberg and Chan laid the groundwork for remaking their philanthropic organization into one focused on AI-powered biomedical research, and its flagship Biohub network in particular. Their move extends a broader retreat from the couple's earlier push into education and social-justice causes, although they'll continue to make donations to local organizations. "I feel like the science work that we've done, the Biohub model in particular, has been the most impactful thing that we have done," Zuckerberg said during an event at the Biohub Imaging Institute in Redwood City in November, according to the Associated Press. "So we want to really double down on that. Biohub is going to be the main focus of our philanthropy going forward." The couple has dedicated, through the Giving Pledge, to give away 99% of their lifetime wealth. Their massive move also underscores how big donors are racing to back science-heavy, tech-centric projects such as peers like the Gates Foundation. The philanthropy started by Bill and Melinda French Gates will shutter in 2045 and has plans to make a record $9 billion in donations this year while remaining primarily focused on health care and disease research. Why CZI had layoffs and its pivot to Biohub. Because the Chan Zuckerberg Initiative has big plans to expand its biomedical and science focus and step a little further back from its original focus areas of education, criminal justice reform, housing, and community development, it now needs employees with expertise in their new coverage areas. While some were able to be assigned to other teams, the organization needed more research-heavy expertise to match the new mission, so some had to be laid off. They received a 60-day notice period and will get a severance package with 16 weeks of base pay, health insurance, and a $10,000 stipend to help with other needs. The layoffs came as part of a decision to concentrate resources on Biohub, a growing network of biomedical research institutes that aims to "cure or prevent all disease," according to Zuckerberg and Chan. It currently operates as a collaborative network of nonprofit research centers, partnering with universities like UC San Francisco, Stanford, UC Berkeley, Northwestern, and Columbia. Biohub is focused on advancing biomedical science, engineering, and artificial intelligence to cure, prevent, or manage all diseases. CZI will continue to hire and grow its team, but with more science-focused roles like researchers, data scientists, computational biologists, and more. Since Biohub's 2016 inception, the couple has donated $4 billion to basic science research, and is on track to double that amount during the next decade, according to the AP. The organization has an operating budget of about $1 billion per year. "We will continue our other philanthropic efforts as well, but the Chan Zuckerberg Initiative will serve as infrastructure and support for our initiatives," the couple wrote in a blog post in November. "There will be many challenges, but we believe that achieving some of humanity's long-term dreams will also come within reach." CZI's shared AI obsession with Meta. Like Zuckerberg's $1.81 trillion tech company Meta, CZI is going all-in on AI-focused research and outcomes. Both his business and philanthropic efforts are now squarely focused on AI, with Meta committed to spending between $115 billion and $135 billion on building "superintelligent" agents for user needs across feeds, ads, and commerce. CZI's Biohub similarly is focused on "frontier AI" and "frontier biology," using large-scale models for virtual cells, immune reprogramming, and disease prediction. With those efforts, Zuckerberg has framed 2026 as AI's transformative year for work at both Meta and CZI. "Accelerating science is the most positive impact we think we can make," Zuckerberg and Chan wrote in the November blog post. "So we're going all in on AI-powered biology for our next chapter."

GenomeWeb
Nov 7th, 2025
CZI Acquires EvolutionaryScale for Biohub

The Chan Zuckerberg Initiative (CZI) has acquired EvolutionaryScale, a company focused on AI algorithms for life sciences, as part of a restructuring to form Biohub, a new entity combining CZI Science and Chan Zuckerberg Biohub network. This will be the main philanthropic focus for Mark Zuckerberg and Priscilla Chan. EvolutionaryScale Cofounder Alex Rives will lead science at Biohub. Financial details of the acquisition were not disclosed.

RamaOnHealthcare
Jul 24th, 2025
Chan Zuckerberg Initiative Introduces New GREmLN Model For Genetics

Chan Zuckerberg Initiative introduces new GREmLN model for genetics.

Forbes
May 13th, 2025
Somite AI Raises $47M for Cell Therapy

Somite AI has raised $47 million in a Series A funding round, led by Khosla Ventures, bringing its total funding to about $60 million. The startup aims to revolutionize cell replacement therapy using its AI platform, DeltaStem, to produce any human cell type. This approach could address diseases like Type 1 Diabetes and muscular disorders. Somite's method involves using semi-permeable capsules to efficiently generate data, enhancing the development of AI models for stem cell biology.

PR Newswire
May 5th, 2025
Psomagen Selected As Key Service Provider, Will Utilize Ultima Genomics' Ug 100™ Sequencer To Accelerate Chan Zuckerberg Initiative'S Billion Cells Project

ROCKVILLE, Md., May 5, 2025 /PRNewswire/ -- Psomagen Inc., a multiomics service laboratory serving academic, pharma, biotech, and clinical customers, will join the Billion Cells Project led by the Chan Zuckerberg Initiative (CZI). The Billion Cells Project aims to develop a landmark single-cell dataset of one billion cells that will be used to train new AI models to advance researchers' understanding of cellular behavior and gene function. Psomagen has begun providing services to participating researchers in April. The project includes collaborations with several other technology partners, including Ultima Genomics, 10x Genomics and Scale Biosciences. Su Hong, CEO of Psomagen, says, "This project represents a transformative step in biomedical research, enabling the identification of novel therapeutic targets and guiding drug development with unparalleled precision. By leveraging AI-powered analysis on vast single-cell datasets, we aim to accelerate the discovery of new ways to restore diseased cells to health

INACTIVE