Full-Time
Director/Sr. Director
Clinical Pharmacology & Pharmacometrics
Confirmed live in the last 24 hours
Develops RNAi-based therapies for diseases
Biotechnology
Senior
Madison, WI, USA + 2 more
Required Skills
Communications
Requirements
- PhD or equivalent in pharmacokinetics, pharmacology or pharmaceutical science
- Track records in clinical pharmacology program leadership with 7+ years of pharmaceutical/Biotech industry experience
- Established knowledge of drug development from Pre-INA to NDA/BLA
- Ability to apply scientific principles to complex situations and provide effective solutions
- Strong verbal communication and document writing skills with clarity of thinking
- Proficiency in non-compartmental analysis of clinical PK data
Responsibilities
- Lead the function of Clinical Pharmacology/Pharmacometrics for multiple programs in Phase 1-3 development
- Contribute to clinical protocols design and execution; analyze data and prepare clinical study reports
- Participate in regulatory interactions with global Health Authorities and prepare documents with submission standards
- Maintain a current understanding of field literature for oligonucleotide therapeutics, and Model-Informed Drug Development (MIDD)
- Provide PK/PD Modeling & Simulations to support dosing strategies for clinical programs
- Provide leadership expertise and mentor junior team members
Arrowhead Pharmaceuticals specializes in developing RNAi-based therapies using their TRiM platform, which leverages various RNA chemistries for tissue-specific targeting, enabling rapid and durable knockdown of disease-causing genes. The TRiM platform also utilizes ligand-mediated delivery, offering potential advantages such as simplified manufacturing, reduced costs, and improved safety.
Company Stage
IPO
Total Funding
$899.9M
Headquarters
Pasadena, California
Founded
2004
Growth & Insights
Headcount