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Executive Director, Early Development Program Leader
Posted on 7/6/2022
INACTIVE
Locations
Cambridge, UK
Experience Level
Entry
Junior
Mid
Senior
Expert
Desired Skills
Leadership
R
Requirements
  • MD, PhD, DVM, PharmD or equivalent advanced degree of relevance
  • 10+ years of experience in the drug development process and leadership experience in academic or industry setting including education where applicable
  • Expertise in the drug development process with particular in-depth know how and experience in the early development space, matrix team leadership, relevant regulatory expectations, and overall drug development principles
  • Successful track record of leading through influence and working across complex, global organizational matrices
  • Deep understanding of the role of basic biology, pharmaceutical optimization, translational medicine, and clinical pharmacology, including exposure-response relationships and dose selection in early development
  • Strong understanding of relevant regulatory health authority expectations and regulations for drug development, with a focus on early development but with an understanding of implications toward full development
  • Working knowledge of all functional areas of exploratory development, including chemistry/biochemistry, biology, toxicology, CMC, translational medicine, early clinical development, etc
  • Demonstrated scientific acumen and mechanistic understanding of pharmacology and disease biology
  • Ability to create a clear purpose, global vision, strategies and key priorities for competing successfully in the evolving pharmaceutical and health care industry
  • Demonstrated ability to lead cross-functional team to execute Development Plans which have global perspective and focus on product differentiation, including opportunities for data driven acceleration
  • Demonstrated ability to objectively assess complex but relatively sparse data sets, make informed decisions and take action in the face of uncertainty
  • Demonstrated ability to successfully present complex programs to senior leaders and influence decision making
  • Experience in successfully managing and leading high performing, cross-functional matrix teams or complex multi-functional organizations
  • Demonstrated ability to coach and mentor others in order to enhance performance and/or facilitate career progression
  • Ability to effectively and seamlessly multi-task, and prioritize across multiple exploratory development assets, with complex strategies and accelerated development timelines
  • Demonstrated ability to successfully and effectively cooperate, collaborate and work across functional boundaries
  • Demonstrated ability to advise and participate in business development due-diligence evaluations and transaction recommendations
Responsibilities
  • Uses an understanding of disease biology, the early-stage drug development process (particularly cross-functional connectivity), and relevant late-stage challenges (e.g., trends in disease area therapeutic advances, and evolving regulatory, patient advocacy and market access environments) to create a vision for each asset, then design and execute effective exploratory development programs in support of the overall R&D portfolio goals
  • Effectively engages cross company expertise and utilizes advisory groups and governance bodies (eg, TRCs, REDOC, PSGT) to define, revise and champion asset development strategies and implementation plans
  • Continually analyzes progress, engages in critical thinking, and asserts strong problem-solving toward delivering key data and interpretation essential for robust debate and rapid, data-driven decision making on assigned projects
  • Delivers high quality assets to Full Development which have the potential for a competitive profile to address the unmet medical needs of patients and to provide favorable shareholder return
  • Ensures the process and output of the team meets established program standards (per PD&C Process expectations, within budget, on schedule, compliant, etc.), while also looking for opportunities to streamline development and enable continuous improvements without compromising quality
  • Engages senior leaders and functional area stakeholders to ensure alignment of program strategy and operational plans with functional area capabilities, and clearly communicates program risks, implications of changes in the competitive landscape and progress toward key milestones
  • Actively provides input to and drives portfolio level strategy for both internal and external opportunities
Bristol-Myers Squibb

10,001+ employees

Biopharmaceutical development company
Company Overview
Bristol-Myers Squibb engages in the discovery, development, licensing, manufacturing, marketing, distribution and sale of pharmaceuticals.