Full-Time

IT Operations Technical Lead

Posted on 10/1/2025

Axle

Axle

201-500 employees

Translational research informatics and data science

Compensation Overview

$140k - $160k/yr

North Bethesda, MD, USA

In Person

Category
IT & Security (2)
,
Required Skills
Kubernetes
Microsoft Azure
Python
ServiceNow
Ruby
AWS
Go
Google Cloud Platform
Requirements
  • 8+ years of IT Operations experience
  • 5+ years of supporting Cloud Services (AWS, Azure, GCP)
  • Bachelor’s degree in computer science, engineering, or similar field
  • Experience working with and securing cloud services such as AWS EC2, EKS, GuardDuty, ELB, ECS, IAM, S3, RDS, CloudTrail, CloudFront, and AWS Config
  • Experience assessing the security of the cloud and Kubernetes environments
  • Knowledge of ITSM tools such as ServiceNow or Remedy
  • Demonstrated knowledge preparing guidance related to Cybersecurity best practices within the framework of NIST publications, ISO 2700 Series, CIS, OWASP, RMF, and the various control families within
  • Experience configuring and maintaining monitoring tools, SIEM’s, IDSs, IPS, etc.
  • Experience with a programming or scripting language such as Ruby, Go, or Python
  • Knowledgeable on zero trust architecture concepts such as Google BeyondCorp
Responsibilities
  • Oversee On-Prem & Cloud daily technical operations
  • Apply appropriate security measures to safeguard government systems by implementing industry-standard best practices adequately and NIH-mandated
  • Assume a technical lead role in the administration and management of infrastructure solutions that are deployed on-prem and in all major cloud service provides in accordance with Security Guidelines
  • Installing, configuring, maintaining, and supporting applications and servers
  • Performing operating system and software installation, testing, patching and upgrades
  • Monitoring the Heath of internal environment and connections
  • Research new technologies that are applicable to current projects and make recommendations to improve performance, optimize operations, and reduce costs
  • Architecting and leading the migration of legacy On-Prem solution migrations to Cloud Environments with High Performance and reliability
  • Assist in managing technology in projects and providing technical guidance or solutions for task completion
  • Participate in technical discussions or review as a technical consultant for solutions feasibility studies (technical alternatives, best packages, supporting architecture best practices, technical risks, breakdown into components, estimations)
  • Continuously collaborate with the Software Development teams in addressing Operational technical debt
  • Conduct periodic security checks/audits in to ensure Environment compliance with Government guidance and directives
  • Develop and guide team members in enhancing their technical capabilities and increasing productivity

Axle Informatics provides specialized informatics solutions for translational research, health informatics, and data science to biomedical research centers and healthcare organizations. Its offerings are customized software and data management platforms that help researchers collect, integrate, analyze, and visualize large research datasets, with end-to-end tools that automate data aggregation and deliver analytics, dashboards, and decision-support features. The company differentiates itself with an integrated, scientifically informed approach that bridges data science with application development, specifically focused on translational research and clinical data work rather than generic software. Axle’s goal is to advance public health by moving biomedical discoveries from the lab to bedside, improving healthcare outcomes.

Company Size

201-500

Company Stage

N/A

Total Funding

N/A

Headquarters

Rockville, Maryland

Founded

2002

Simplify Jobs

Simplify's Take

What believers are saying

  • Axle won $21M NIH NCATS STPS contract for scientific support in 2026.
  • Axle secured 3-year NIAID VRC/NIC task beating one bidder recently.
  • Axle’s ML pipeline boosted NIH funding by 3% averting 20% cuts.

What critics are saying

  • NIH FY2026 cuts slash 15% translational research funding in 3-6 months.
  • Tempus AI captures 25% NIH bioinformatics contracts in 12-18 months.
  • DNAnexus federated platform halts 40% Axle deployments in 6-9 months.

What makes Axle unique

  • Axle deploys fine-tuned LLMs for biomedical NLP and sentiment analysis.
  • Axle provides Healthcare Authentication Solution reducing fraud in privacy-first care.
  • Reid Simon leads AI, Cloud, and Cybersecurity expansions at NIH institutes.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Paid Vacation

Paid Holidays

401(k) Company Match

Educational Benefits for Career Growth

Employee Referral Bonus

Flexible Spending Accounts

Company News

W.W. Grainger, Inc.
Jul 25th, 2023
“Octo awarded $64.7M IT Infrastructure Call Order to support NCI’s Cancer research”

Octo, in partnership with Unissant, Axle Informatics, and TRex, has been awarded an IT Infrastructure and Operations Call Order to support the NCI’s OCIO.

GlobeNewswire
Jan 12th, 2023
Digital Pathology Market Worth $1.86 Billion by 2030 -

For instance, in May 2020, Indica Labs (U.S.), a provider of digital pathology solutions, collaborated with information technology consulting companies, Octo (U.S.) and Axle Informatics (U.S.) and the National Institutes of Health (NIH) (U.S.), to develop an online collection of high-resolution histopathology images of tissues from COVID-19 patients using Indica’s HALO Link platform.

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