Full-Time

Data Scientist

AffirmedRx

AffirmedRx

51-200 employees

Public-benefit PBM lowering prescription costs

No salary listed

Remote in USA

Remote

Bachelor's

Category
Data & Analytics (1)
Required Skills
LLM
Streamlit
Data Lake
Python
SQL
Machine Learning
Data Engineering
Pandas

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Requirements
  • Degree in a quantitative field (data science, statistics, computer science, applied math) or equivalent experience
  • 2–3 years of experience using Python and SQL for data analysis, machine learning, NLP, data quality, and record-matching solutions. Data modeling experience in PBM and/or healthcare industry in general preferred
  • Strong Python for data science and ML (e.g., pandas plus a modeling stack), and proficiency in SQL
  • Demonstrated experience building and validating ML models, including feature engineering and model explainability
  • Experience with NLP techniques (sentiment analysis, topic modeling) and with applying AI/LLM tooling to real workflows, including output validation
  • Experience with entity resolution / probabilistic record matching and data-quality analysis
  • Comfort working with a modern cloud data warehouse and data lake, and partnering with data engineering on production hand-off
  • Healthcare, pharmacy benefit management (PBM), or claims-data experience
  • Familiarity with pharmacy data concepts (NDC, GPI, ATC, formulary tiers, prior authorization, rebates)
  • Experience with compliance-driven reporting (e.g., URAC / PQA measures)
  • Experience building analytical front ends or dashboards (e.g., Streamlit, BI tools) for non-technical stakeholders
  • Willingness and ability to travel (10%-20%)
Responsibilities
  • Build predictive and prescriptive ML models for pharmacy cost and risk (e.g., forecasting second-year member spend), including feature engineering, model selection, and explainability analysis (e.g., SHAP-based feature attribution)
  • Develop member-level risk and comorbidity scoring, mapping drug identifiers (NDC → ATC) to clinical conditions and severity weights, and validating outputs against edge cases
  • Apply ML to automate high-effort clinical operations processes (e.g., prior-authorization override automation), moving manual workflows into rules-based and model-driven pipelines
  • Use AI/NLP to analyze unstructured member and clinical text — sentiment analysis, topic modeling, and tokenization of open-ended survey and feedback data
  • Apply AI tooling (LLMs / copilots and internal AI services) to automate clinical policy and documentation workflows, including prompt design, output validation, and controls against hallucination and format drift
  • Contribute to the organization’s broader AI direction: evaluating models, defining evaluation/answer-key datasets, and building drift and validation checks for AI outputs
  • Design and maintain probabilistic (fuzzy) matching logic to assign and reconcile unique member identifiers across carriers and source systems, including collision handling, cluster analysis, and audit/logging frameworks
  • Monitor and improve match rates, investigate false positives and fragmentation, and document data lineage and safeguards against duplicates
  • Produce clinical and pharmacy analytics such as medication adherence and persistence (drug-, class-, and NDC-level), aligned to compliance requirements (e.g., URAC / PQA measures)
  • QA and validate reporting products (e.g., pharmacy trend dashboards, PMPM metrics), reconciling data-point discrepancies across source systems
  • Build analytical tools and prototypes (e.g., formulary/tier decision tools and cost-comparison tools), including lightweight front ends (e.g., Streamlit) for sales, clinical, and pricing use
  • Deliver validated datasets and tables into the data warehouse in partnership with data engineering, and support the transition of prototypes into production
  • Own QA and validation for analytical outputs, including auditing of claims files and validation of model results before release
  • Document models, logic, data sources, schedules, and troubleshooting steps to make work reproducible and auditable
  • Collaborate across clinical, reporting, pricing, client-success, and engineering stakeholders to gather requirements and translate them into analytical specifications

AffirmedRx provides pharmacy benefit management services by negotiating drug pricing, discounts, and rebates with manufacturers and pharmacies for employers and health plans. The company operates by passing 100% of these negotiated savings directly to its clients, removing the hidden fees and markups typically found in the complex pharmacy ecosystem. Unlike traditional competitors, it is a Public Benefit Corporation committed to total transparency and a pass-through pricing model rather than profiting from spread pricing. Its goal is to simplify the benefits process and ensure patients have access to the safest medications at the lowest possible cost.

Company Size

51-200

Company Stage

N/A

Total Funding

N/A

Headquarters

Louisville, Kentucky

Founded

2021

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Simplify Jobs

Simplify's Take

What believers are saying

  • July 2026 formulary updates show active client management and product utilization.
  • LinkedIn listed five open roles in 2026, including formulary and product leadership.
  • AffirmedRx's 2026 client-facing pages and Spanish member portal signal ongoing employer expansion.

What critics are saying

  • FTC's February 2026 PBM crackdown raises regulatory pressure on rebate-dependent rivals.
  • Purdue, H&R Block, and other employers expose implementation risk through member complaints.
  • Flat-fee transparency struggles against CVS Caremark, Express Scripts, and OptumRx scale.

What makes AffirmedRx unique

  • 2023 PBGH sale renamed EmsanaRx to AffirmedRx, sharpening fiduciary-first positioning.
  • AffirmedRx Plus uses a flat $3 fee and direct MCCP collaboration.
  • 2026 CAA readiness report says nine PBM contracts cleared 90 on fiduciary alignment.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Company Equity

Remote Work Options

Growth & Insights and Company News

Headcount

6 month growth

35%

1 year growth

35%

2 year growth

35%
The Lane Report
Aug 12th, 2026
AffirmedRx is the first PBM to reach the top 10 of Inc. 5000 fastest growing private companies.

AffirmedRx is the first PBM to reach the top 10 of Inc. 5000 fastest growing private companies. August 12, 2026 Louisville, Ky. (August 12, 2026) - AffirmedRx today announced it has been ranked No. 5 on the 2026 Inc. 5000, the annual list of the fastest-growing private companies in America. The list is the most prestigious ranking of the nation's most successful independent and entrepreneurial businesses, recognizing companies that have achieved remarkable growth while driving innovation, creating jobs, and shaping the future of the economy. Past honorees include companies such as Microsoft, Meta, Chobani, Oracle, and Patagonia. AffirmedRx is the only Pharmacy Benefit Manager (PBM) that is also a Public Benefits Corporation (PBC). Delivering a unique member-first approach to pharmacy benefits and operating on a simple, flat administrative fee model. "When we started this company, the big PBMs controlled the market and employers had no real alternative. We knew disrupting the status quo would take years of work. We also hit the market at the right time, because consultants, brokers, and employer groups were actively looking for something better," says Greg Baker, CEO of AffirmedRx. "We are proud to be ranked No. 5 in the country, No. 1 in Kentucky, and No. 2 in Healthcare and Medical. This recognition is a testament to our vision: a pharmacy benefit industry built on trust, where the people we serve feel cared for every day." This year's Inc. 5000 recognizes a new class of companies redefining what growth looks like. From AI and advanced manufacturing to healthcare, consumer products, and professional services, these businesses are expanding their impact, creating jobs and proving that entrepreneurial ambition continues to fuel the U.S. economy. Among the 5,000 companies on the list, the median three-year revenue growth rate was 130%, and those companies have collectively added more than 627,208 jobs to the U.S. economy over the past three years. "Every company on the Inc. 5000 has a story of perseverance, smart decision making, and a refusal to sit still," says Mike Hofman, editor-in-chief of Inc. "Their growth reflects more than strong financial performance-it reflects creativity, resilience, and the customer focus required to build companies that make a lasting impact. We congratulate all honorees on this significant achievement." For the full Inc. 5000 list, honoree company profiles, and a searchable database by industry and location, please visit: www.inc.com/inc5000. Inc. 5000 List Methodology Companies on the 2026 Inc. 5000 are ranked according to percentage revenue growth from 2022 to 2025. To qualify, companies must have been founded and generating revenue by March 31, 2022. They must be U.S.-based, privately held, for-profit, and independent - not subsidiaries or divisions of other companies - as of December 31, 2025. (Since then, some on the list may have gone public or been acquired.) The minimum revenue required for 2022 is $100,000; the minimum for 2025 is $2 million. As always, Inc. reserves the right to decline applicants for subjective reasons. About Inc. Inc. is the leading media brand and playbook for the entrepreneurs and business leaders shaping our future. Through its journalism, Inc. aims to inform, educate, and elevate the profile of its community: the risk-takers, the innovators, and the ultra-driven go-getters who are creating the future of business. Inc. is published by Mansueto Ventures LLC, along with fellow leading business publication Fast Company. For more information, visit www.inc.com. About AffirmedRx AffirmedRx is the only Pharmacy Benefit Manager structured as a Public Benefit Corporation. Partnering with employers, health plans, hospital systems, and other payers seeking a fully transparent, clinically driven, and member-first approach to pharmacy benefits, AffirmedRx ensures every dollar is accounted for and employer groups have complete visibility and access to their data and is a positive advocate for change in the industry. By delivering full transparency, data access and financial clarity, AffirmedRx prioritizes patients over profits. We simplify the complexities of filling prescriptions so patients can confidently access the best care to get and stay healthy. To learn more, please visit www.affirmredrx.com