Scientist – Discovery Biology & Protein Biochemistry
Confirmed live in the last 24 hours
Palo Alto, CA, USA
Experience Level
Biology & Biotech
  • Ph.D., MD, or Ph.D./MD degree and expertise in a relevant scientific field (e.g., biochemistry, biophysics, molecular biology, chemical biology, chemistry, structural biology). Prior industry experience is desirable but not required
  • Experience and familiarity with techniques used for protein expression, purification, labeling, and characterization
  • Experience with a wide range of biophysical (mass spectrometry (MS), surface plasmon resonance (SPR), microscale thermophoresis (MST), isothermal titration calorimetry (ITS), protein thermal shift (PTS), dynamic light scattering (DLS)) and plate-based biochemical (FRET, MSD, ELISA) techniques
  • Experience with other molecular and cellular biology techniques, such as functional assay development, immunohistochemistry (IHC), Western blot, qPCR, etc
  • Experience with biochemical/biophysical/immuno-assay development and high-throughput screening is a strong plus
  • Strong knowledge of chemistry concepts and structure biology, including an understanding of structure-activity relationships (SAR) and structure-based drug design
  • Demonstrated record of achievement as evidenced by first-author publications, grants, scholarships, or, awards
  • Use a variety of biochemical, biophysical, and pharmacological techniques to advance multiple small molecule drug candidates from discovery research to clinical development
  • Develop, optimize, troubleshoot, and execute novel assays for preclinical drug discovery including assays for in vitro, cellular, and animal plasma samples
  • Drive basic research towards the clinic at hyperspeed
  • Independently design, execute and analyze experiments within our top-notch laboratory
  • Communicate findings and implications to senior leadership
  • Help drive overall pre-clinical strategy
  • No matter your role at BridgeBio, successful team members are:
  • Patient Champions, who put patients first and uphold strict ethical standards
  • Entrepreneurial Operators, who drive toward practical solutions and have an ownership mindset
  • Truth Seekers, who are detailed, rational, and humble problem solvers
  • Individuals Who Inspire Excellence in themselves and those around them
  • High-quality executors, who execute against goals and milestones with quality, precision, and speed
Desired Qualifications
  • Experience with multichannel pipettes and semi-automatic pipetting station is a plus