Sr. Scientist II



201-500 employees

Develops drugs for muscle-related debilitating diseases


$180,000 - $220,000


San Bruno, CA, USA

  • Doctorate (PhD) with 8+ years of experience in Pharmaceutical Sciences or related field
  • In-vivo and in-vitro drug metabolism including mass balance, stability evaluation, structural elucidation, enzymology, drug-drug interaction (DDI), metabolic enzyme inhibition and induction
  • Experience conducting and implementing bioanalysis (BA) methodology in the ADME, PK and PD areas (regulated and non-regulated)
  • Proficiency in applying pharmacokinetic (PK) principles to both noncompartmental and compartmental analysis within PK/TK/PD studies
  • Proficient understanding and application of cytochrome enzyme inhibition, induction, drug transporter functionality, and their effects on pharmacokinetics (PK) and drug-drug interactions (DDI)
  • Expertise in in-vitro - in-vivo extrapolations (IVIVE) and allometric principles, with a focus on utilizing these methods for accurate predictions of first-in-human dose and exposure
  • Knowledgeable of current regulatory landscape in DMPK area of expertise including contribution to regulatory filings (IND, NDA, investigator brochure)
  • Lead the formulation and execution of comprehensive DMPK and pharmacokinetics-pharmacodynamics (PKPD) strategies
  • Act as the primary DMPK and bioanalytical representative within project teams
  • Employ sophisticated analysis and synthesis techniques to integrate in silico, physicochemical, ADME, and DMPK data
  • Collaborate seamlessly with cross-functional project team members
  • Engage actively in partnership with key stakeholders to contribute to the development of robust PK/PD models
  • Lead the coordination and oversight of Drug Metabolism, PK, and PKPD studies
  • Contribute to the preparation of Drug Metabolism, PK, and PKPD reports

Cytokinetics stands out as a leader in the biopharmaceutical industry with its specialized focus on muscle biology and the development of first-in-class muscle activators and next-in-class muscle inhibitors, addressing debilitating diseases where muscle performance is compromised. The company's commitment to positively impacting patients' lives is reflected in its culture, fostering resilience and fortitude among its employees. Recognized as a top workplace by the San Francisco Business Times, Fortune, and Great Place to Work-Certified, Cytokinetics offers a supportive and rewarding environment that encourages innovation and industry leadership.

Company Stage


Total Funding



South San Francisco, California



Growth & Insights

6 month growth


1 year growth


2 year growth