ArsenalBio, a privately held, clinical-stage programmable cell therapy company engineering advanced CAR T therapies for solid tumors, is seeking a talented Scientist to work in our South San Francisco office.
ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer. With our programmable and computationally driven approach, our team is engineering living medicines to attack cancer’s inherent multi-faceted nature and overcome the challenges of addressing solid tumors with cell therapy.
Driven by a collective of diverse experts across immunology, synthetic biology, molecular biology, automation and computational biology, we are united in purpose to deliver radical breakthroughs for people with cancer, and prioritize the team’s outcomes over individual goals to achieve our company mission – together.
We are seeking a motivated Scientist to participate in construct design, DNA construction, and the development of new technologies & capabilities in ArsenalBio’s Molecular Biology team as a part of our efforts to develop and commercialize curative immune cell therapies.
What You Will Do:
- Design and build DNA constructs and libraries encoding synthetic circuits and therapeutic modules for high-throughput functional screens
- Provide expertise in cloning & broader molecular biology applications and strategies as functional point lead for product and program development
- Develop, operationalize, and optimize automation-enabled capabilities to scale DNA construction and characterization
- Work with interdisciplinary teams to establish and test novel adoptive cell therapy approaches
- Collaborate with program management to set milestones, deliverables, and timelines for active products and programs
- Maintain familiarity with the relevant current literature and its application to synthetic biology and genome engineering
- Coordinate tasks across multiple projects, demonstrating prioritization and planning
- Interpret and effectively execute experiments in line with project timelines and goals
What Will You Bring:
- PhD in molecular biology or a related field, or Masters with 5+ years relevant experience in industry or academia, or Bachelors with 7+ years of relevant research experience in industry or academia
- Experience in designing complex, multi-part vectors for gene expression, genetic reporter systems, and genome engineering applications
- Experience in devising sound cloning strategies for complex DNA construction
- Experience developing and optimizing protocols for nucleic acid cloning, amplification, modification and analysis
- Experience optimizing and developing protocols for DNA assembly and library construction for applications such as synthetic biology, functional genomics and/or protein engineering
- Experience with automation and HTP cloning workflows
- Working knowledge of next-generation sequencing technologies and workflows
- Entrepreneurial behaviors demonstrated by agility, accountability, transparency, resourcefulness, and ability to get things done
- Ability to quickly learn new skills and knowledge on the job, demonstrate productivity, and deliver high-quality results
- Growth mindset with eagerness to learn & adapt, ability to think outside the box, creative approach to problem solving, and comfort in working with ambiguous data in an open-ended, exploratory process
What We Will Offer You:
An opportunity to work with the best talent in the field of cell therapy, and be part of ONE TEAM to advance therapies to patients who need it most.
ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge.
We have a robust mentorship program, and comprehensive development tools to help employees take control of their career paths and grow into their best selves. ArsenalBio believes in investing in the well-being of our employees - both at work and at home, as they are our greatest asset. They bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.
We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
The estimated base salary offer for the preferred primary location of San Francisco Bay area ranges from $108,600- $133,000.
Salary ranges for other locations may vary from this range. Base pay offered may vary depending on job related knowledge, experience, education, and location. In addition to these factors, we believe in the importance of pay equity and consider internal equity of our current employees as part of any final offer.
To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.
